Patents by Inventor Patrick Depreux

Patrick Depreux has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminoalkyl benzoxazolinones and benzothiazolinones
    Patent number: 5534511
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, X and n are as defined in the description, the optical isomers thereof, and the addition salts thereof with a pharmaceutically acceptable acid or base and medicinal product containing the same, useful for treating a mammal afflicted with a pathology associated with the sigma receptors.
    Type: Grant
    Filed: March 21, 1995
    Date of Patent: July 9, 1996
    Assignee: Adir et Compagnie
    Inventors: Ange Mouithys-Mickalad, Patrick Depreux, Daniel Lesieur, Gerard Adam, Daniel-Henri Caignard, Pierre Renard, Marie-Claire Rettori
  • (Aryl(alkyl)carbonyl)-heterocyclic compounds and their use in the treatment of anxiety and depression
    Patent number: 5534517
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## wherein Ar, n, B and A are as defined in the description, to their optical isomers, and to their addition salts there of with a pharmaceutically-acceptable acid or base. The compounds are useful for treating or preventing anxiety and depression.
    Type: Grant
    Filed: August 26, 1994
    Date of Patent: July 9, 1996
    Assignee: Adir Et Compagnie
    Inventors: Ousmane Diouf, Daniel Lesieur, Patrick Depreux, Beatrice Guardiola-Lemaitre, Daniel-Henri Caignard, Pierre Renard, Gerard Adam
  • Aminoalkyl benzothiazolinones
    Patent number: 5512569
    Abstract: The invention relates to the compounds of formula (I): ##STR1## in which R.sub.1 and R.sup.2 are as defined in the description, the optical isomers thereof,and an addition salt thereof with a pharmaceutically-acceptable acid or base, and medicinal product useful for treating a mammal afflicted with a disease associated with sigma receptors.
    Type: Grant
    Filed: March 21, 1995
    Date of Patent: April 30, 1996
    Assignee: Adir et Compagnie
    Inventors: Hamid A. Mansour, Thierry Taverne, Raymond Houssin, Isabelle Lesieur, Patrick Depreux, Geard Adam, Daniel-Henri Caignard, Pierre Renard, Marie-Claire Rettori
  • Naphthylethylureas and naphthylethylthioureas
    Patent number: 5449689
    Abstract: A compound selected from those of formula (I): ##STR1## in which the meanings of R, R.sub.1, R.sub.2 and X are as defined in the specification, andmedicinal products containing the same which are useful in treating or in preventing a disorder of the melatoninergic system.
    Type: Grant
    Filed: December 20, 1994
    Date of Patent: September 12, 1995
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Said Yous, Patrick Depreux, Gerard Adam, Pierre Renard, Bruno Pfeiffer, Beatrice Guardiola-Lemaitre
  • Naphthylethylureas and naphthylethylthioureas
    Patent number: 5449690
    Abstract: A compound selected from those of formula (I): ##STR1## in which the meanings of R, R.sub.1, R.sub.2 and X are as defined in the specification, and medicinal products containing the same which are useful in treating or in preventing a disorder of the melatoninergic system.
    Type: Grant
    Filed: December 20, 1994
    Date of Patent: September 12, 1995
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Said Yous, Patrick DePreux, Gerard Adam, Pierre Renard, Bruno Pfeiffer, Beatrice Guardiola-Lemaitre
  • Benzoxazolinonyl substituted alkylamines
    Patent number: 5436348
    Abstract: Compounds of general formula (I): ##STR1## where R, X, A, B and p are defined in the description. Medicinal products useful for treating sleep disorders comprising the same.
    Type: Grant
    Filed: April 5, 1994
    Date of Patent: July 25, 1995
    Assignee: Adir et Compagnie
    Inventors: Said Yous, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Naphthylalkylamines
    Patent number: 5420158
    Abstract: The invention relates to a compound selected from those of general formula (I): ##STR1## in which R, R.sub.1, R.sub.2 and R.sub.3 are as defined in the specification, an optical isomer, and an addition salt thereof with a pharmaceutically-acceptable base.Medicinal product which is useful in the treatment of disorders linked to abnormal melatonin activity.
    Type: Grant
    Filed: March 23, 1993
    Date of Patent: May 30, 1995
    Assignee: Adir et Compagnie
    Inventors: Said Yous, Daniel Lesieur, Patrick Depreux, Beatrice Guardiola-Lemaitre, Gerard Adam, Pierre Renard, Daniel H. Caignard
  • Naphthylethylureas
    Patent number: 5389683
    Abstract: A compound selected from those of formula (I): ##STR1## in which the meanings of R, R.sub.1, R.sub.2 and X are as defined in the specification, andmedicinal products containing the same which are in treating or in preventing a disorder of the melatoninergic system.
    Type: Grant
    Filed: August 14, 1992
    Date of Patent: February 14, 1995
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Said Yous, Patrick Depreux, Gerard Adam, Pierre Renard, Bruno Pfeiffer, Beatrice Guardiola-Lemaitre
  • (Aryl(alkyl)carbonyl)-heterocyclic compounds, compositions and use
    Patent number: 5387586
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## wherein Ar, n, B and A are as defined in the description, to their optical isomers, and to their addition salts there of with a pharmaceutically-acceptable acid or base.Medicinal product which is useful for treating pain and treating or preventing pathologies which require psychotropic agents.
    Type: Grant
    Filed: March 4, 1994
    Date of Patent: February 7, 1995
    Assignee: Adir et Compagnie
    Inventors: Ousmane Diouf, Daniel Lesieur, Patrick Depreux, Beatrice Guardiola-Lemaitre, Daniel-Henri Caignard, Pierre Renard, Gerard Adam
  • 2-(alkoxy benzothiazolinon-3yl) ethylamines
    Patent number: 5386034
    Abstract: Compounds of general formula (I): ##STR1## where R, X, A, B and p are defined in the description. Medicinal products. Useful for treating sleep disorders comprising the same.
    Type: Grant
    Filed: June 15, 1993
    Date of Patent: January 31, 1995
    Assignee: Adir et Compagnie
    Inventors: Said Yous, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Naphthylethylureas and naphthylethylthioureas
    Patent number: 5385944
    Abstract: A compound selected from those of formula (I): ##STR1## in which the meanings of R, R.sub.1, R.sub.2 and X are defined in the specification, andmedicinal products containing the same which are useful in treating or in preventing a disorder of the melatoninergic system.
    Type: Grant
    Filed: April 27, 1993
    Date of Patent: January 31, 1995
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Said Yous, Patrick Depreux, Gerard Adam, Pierre Renard, Bruno Pfeiffer, Beatrice Guardiola-Lemaitre
  • Arylethylamine compounds
    Patent number: 5380750
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which Ar', R.sub.1 and R.sub.2 are as defined in the specification, an optical isomer,and an addition salt thereof with a pharmaceutically-acceptable acid or base.Medicinal product which is useful in treating or in preventing a disorder of the melatoninergic system.
    Type: Grant
    Filed: July 19, 1993
    Date of Patent: January 10, 1995
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Said Yous, Patrick Depreux, Jean Andrieux, Gerard Adam, Daniel H. Caignard, Beatrice Guardiola
  • Naphthalene amides and sulphonamides, processes for their preparation and pharmaceutical compositions containing them
    Patent number: 5332759
    Abstract: The invention relates to compounds of the general formula (I): ##STR1## wherein R.sub.3 represents a group ##STR2## R.sub.1, R.sub.2, R.sub.6, R.sub.7 being as defined in the description. Medicinal product useful in treating a disorder due to vasodilatation of the vascular system.
    Type: Grant
    Filed: January 21, 1993
    Date of Patent: July 26, 1994
    Assignee: Adir et Compagnie
    Inventors: Patrick Depreux, Daniel Lesieur, Habib Abdellaoui, Beatrice Guardiola, Gerard Adam, Pierre Renard, Bruno Pfeiffer
  • Benzoxazolinonyl alkylamides
    Patent number: 5326775
    Abstract: Compounds of general formula (I): ##STR1## where R, X, A, B and p are defined in the description. Medicinal products useful for treating sleep disorders comprising the same.
    Type: Grant
    Filed: April 28, 1993
    Date of Patent: July 5, 1994
    Assignee: Adir et Compagnie
    Inventors: Said Yous, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Benzoxazalinonyl and benzothiazolinonyl ethyl isonicotine amides and piperidonamides
    Patent number: 5322849
    Abstract: Compounds of general formula (I): ##STR1## where R, X, A, B and p are defined in the description. Medicinal products useful for treating sleep disorders comprising the same.
    Type: Grant
    Filed: April 28, 1993
    Date of Patent: June 21, 1994
    Assignee: Adir Et Compagnie
    Inventors: Said Yous, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Benzoxazolinonyl and benzothiazolinonyl ethyl morpholinoacetamides
    Patent number: 5322843
    Abstract: Compounds of general formula (I): ##STR1## wherein R, X, A, B and p are defined in the description. Medicinal products useful for treating sleep disorders comprising the same.
    Type: Grant
    Filed: April 28, 1993
    Date of Patent: June 21, 1994
    Assignee: Adir et Compagnie
    Inventors: Said Yous, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Benzofuran ethylamine compounds
    Patent number: 5308866
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which Ar', R.sub.1 and R.sub.2 are as defined in the specification, an optical isomer,and an addition salt thereof with a pharmaceutically-acceptable acid or base.Medicinal product which is useful in treating or in preventing a disorder of the melatoninergic system.
    Type: Grant
    Filed: July 19, 1993
    Date of Patent: May 3, 1994
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Said Yous, Patrick Depreux, Jean Andrieux, Gerard Adam, Daniel H. Caignard, Beatrice Guardiola
  • New heterocycle-substituted alkylamides
    Patent number: 5300507
    Abstract: Compounds of general formula (I): ##STR1## where R, X, A, B and p are defined in the description. Medicinal products useful for treating sleeping disorders comprising the same.
    Type: Grant
    Filed: April 28, 1993
    Date of Patent: April 5, 1994
    Assignee: Adir et Compagnie
    Inventors: Said Yous, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Aminoalkyl benzoxazine and benzthiazine compounds having a high 5-HT.sub.1A affinity
    Patent number: 5296477
    Abstract: Compounds of general formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, n, X and A are defined in the description.Medicinal products containing the same are useful as antidepressives or anxiolytics due to their 5-HT1A receptor agonist activity.
    Type: Grant
    Filed: December 1, 1992
    Date of Patent: March 22, 1994
    Assignee: Adir et Compagnie
    Inventors: Thierry Taverne, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Arylethylamine compounds
    Patent number: 5276051
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which Ar', R.sub.1 and R.sub.2 are as defined in the specification, an optical isomer,and an addition salt thereof with a pharmaceutically-acceptable acid or base.Medicinal product which is useful in treating or in preventing a disorder of the melatoninergic system.
    Type: Grant
    Filed: August 12, 1992
    Date of Patent: January 4, 1994
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Said Yous, Patrick Depreux, Jean Andrieux, Gerard Adam, Daniel H. Caignard, Beatrice Guardiola