Abstract: There are disclosed &bgr;-sheet mimetics and methods relating to the same for imparting or stabilizing the &bgr;-sheet structure of a peptide, protein or molecule. In one aspect, &bgr;-sheet mimetics are disclosed having utility as protease inhibitors in general and, more specifically, as serine protease inhibitors such as thrombin, elastase and Factor X inhibitors. In one embodiment, the &bgr;-sheet mimetic is a thrombin inhibitor.

Abstract: There are disclosed &bgr;-sheet mimetics and methods relating to the same for imparting or stabilizing the &bgr;-sheet structure of a peptide, protein or molecule. In one aspect, &bgr;-sheet mimetics are disclosed having utility as protease inhibitors in general and, more specifically, as serine protease inhibitors such as thrombin, elastase and Factor X inhibitors. In one embodiment, the &bgr;-sheet mimetic is a thrombin inhibitor.

Abstract: A pet shelter that enables efficient stacking of multiple. The shelter comprises a bottom section and a top section which nest together when stacked.

Abstract: A pet shelter that enables efficient stacking of multiple shelters in a bottom-top-bottom-top-bottom-etc. arrangement is provided. The shelter comprises a bottom section and a top section. Both the top and bottom sections are preferably hollow rectangular boxes with one missing side. Both sections have sloping sidewalls and a substantially U-shaped opening in one sidewall. The sidewalls of the top and bottom sections slope at roughly equal angles. The legs of the U-shaped openings are bent at roughly equal angles on both the top and bottom sections. The height of the top section is roughly equal to the height of the bottom section. The roof of the top section has a very gradual slope, such that the peak of the roof does not obstruct insertion of a top section into a bottom section. Thus, the top and bottom sections are configured such that an inverted top section fits snugly within an interior of a bottom section, and a bottom section fits snugly within an interior of an inverted top section.

Abstract: A method of increasing location accuracy in an inertial navigational device (100) is described herein. The navigational device (100) generates real-time data to depict its location. The data comprises at least one of sensor data, motion data, and location data. The navigational device (100) transmits the real-time data to a second device (104) in a real-time fashion. The navigational device (100) receives an update message from the second device (104), based on a comparison of the real-time data generated by the navigational device (100) against a second set of data. The navigational device (100) adjusts its depicted location based on the update message in order to increase the location accuracy of the navigational, device (100). Alternatively, the navigational device (100), absent the second device (104), can compare the real-time data generated against the second set of data internally and adjust its depicted location accordingly.

Abstract: A method of increasing location accuracy in an inertial navigational device (100) is described herein. The navigational device (100) generates real-time data to depict its location. The data comprises at least one of sensor data, motion data, and location data. The navigational device (100) transmits the real-time data to a second device (104) in a real-time fashion. The navigational device (100) receives an update message from the second device (104), based on a comparison of the real-time data generated by the navigational device (100) against a second set of data. The navigational device (100) adjusts its depicted location based on the update message in order to increase the location accuracy of the navigational device (100). Alternatively, the navigational device (100), absent the second device (104), can compare the real-time data generated against the second set of data internally and adjust its depicted location accordingly.

Abstract: A pet shelter that enables efficient stacking of multiple shelters in a bottom-top-bottom-top-bottom-etc. arrangement is provided. The shelter comprises a bottom section and a top section. Both the top and bottom sections are,preferably hollow rectangular boxes with one missing side. Both sections have sloping sidewalls and a substantially U-shaped opening in one sidewall. The sidewalls of the top and bottom sections slope at roughly equal angles. The legs of the U-shaped openings are bent at roughly equal angles on both the top and bottom sections. The height of the top section is roughly equal to the height of the bottom section. The roof of the top section has a very gradual slope, such that the peak of the roof does not obstruct insertion of a top section into a bottom section. Thus, the top and bottom sections are configured such that an inverted top section fits snugly within an interior of a bottom section, and a bottom section fits snugly within an interior of an inverted top section.

Abstract: A first device (104) receives a first set of data from an inertial navigational device (100). The first set of data comprises at least one of sensor data, motion data, and location data, and is real-time output from the inertial navigational device (100). The first device (104) also receives a second set of data from a secondary source. The second set of data also comprises at least one of sensor data, motion data, and location data. The first device (104) generates an update message based on comparing the first set of data against the second set of data in order to improve location accuracy of the inertial navigational device (100). Optionally, the first device (104) can transmit the update message to the inertial navigational device (100).

Abstract: A pet shelter that enables efficient stacking of multiple shelters in a bottom-top-bottom-top-bottom-etc. arrangement is provided. The shelter comprises a bottom section and a top section. Both the top and bottom sections are preferably hollow rectangular boxes with one missing side. Both sections have sloping sidewalls and a substantially U-shaped opening in one sidewall. The sidewalls of the top and bottom sections slope at roughly equal angles. The legs of the U-shaped openings are bent at roughly equal angles on both the top and bottom sections. The height of the top section is roughly equal to the height of the bottom section. The roof of the top section has a very gradual slope, such that the peak of the roof does not obstruct insertion of a top section into a bottom section. Thus, the top and bottom sections are configured such that an inverted top section fits snugly within an interior of a bottom section, and a bottom section fits snugly within an interior of an inverted top section.

Abstract: There are disclosed &bgr;-sheet mimetics and methods relating to the same for imparting or stabilizing the &bgr;-sheet structure of a peptide, protein or molecule. In one aspect, &bgr;-sheet mimetics are disclosed having utility as protease inhibitors in general and, more specifically, as serine protease inhibitors such as thrombin, elastase and Factor X inhibitors. In one embodiment, the &bgr;-sheet mimetic is a thrombin inhibitor.

Abstract: In operation of a support for a patient's body, used in medical or veterinary treatment, which applies alternating-pressure to the body in order to reduce or minimize the risk of pressure sores caused by prolonged pressure on the skin, inflatable cells of the support are inflated and deflated cyclically in a predetermined sequence. To provide improved effect in relieving or preventing pressure sores, the cells are deflated in the sequence in such a manner that the interior pressure falls from 10 mmHg (135 Pa) to 0 mmHg in a time period of not more than 15 s. Preferably the interior pressure falls to below 0 mmHg (ambient atmospheric pressure). A vacuum pump or pumps may be employed to achieve this result.