Patents by Inventor Patrick E. MacAulay
Patrick E. MacAulay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8540694Abstract: Systems and methods for delivering drugs or other substances to target locations outside of blood vessel lumens or other body lumens. In some embodiments, a catheter having a penetrator is advanced into the body lumen and the penetrator is then advanced from the catheter toward a target location outside of that body lumen. The substance is then delivered through a the penetrator itself or through a delivery catheter that has been advanced through the penetrator to the target location. In other embodiments, the blood vessel or other body lumen is blocked at spaced-apart first and second locations and a quantity of the substance is introduced into the closed-off body lumen between the blocked first and second locations. The substance then diffuses into or through the wall of the vessel or body conduit to reach the target location.Type: GrantFiled: December 27, 2011Date of Patent: September 24, 2013Assignee: Medtronic Vascular, Inc.Inventors: J. Christopher Flaherty, Joshua Makower, Philip C. Evard, Patrick E. Macaulay, Jason B. Whitt, Robert C. Colloton, K. Angela Macfarlane
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Patent number: 8414645Abstract: Delivery devices and methods for percutaneously delivering a prosthetic valve to the heart of a patient. These prosthetic valves may be configured to provide complimentary features that promote optimal placement of the prosthetic valve in a native heart valve, such as the aortic valve, mitral valve, pulmonic valve, and/or tricuspid valve. The delivery device includes a release sheath assembly housed within an outer delivery sheath. A release sheath component of the assembly captures a portion of the prosthetic valve to the delivery device, and effectuates complete release of the prosthetic valve with retraction of the outer sheath.Type: GrantFiled: August 27, 2010Date of Patent: April 9, 2013Assignee: Medtronic, Inc.Inventors: Joshua Dwork, Patrick E. Macaulay, Gianfranco M. Pellegrini, Finn O. Rinne, Richard Spork, Don Huy Tran, Nathan B. Wiemeyer
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Publication number: 20120172838Abstract: Systems and methods for delivering drugs or other substances to target locations outside of blood vessel lumens or other body lumens. In some embodiments, a catheter having a penetrator is advanced into the body lumen and the penetrator is then advanced from the catheter toward a target location outside of that body lumen. The substance is then delivered through a the penetrator itself or through a delivery catheter that has been advanced through the penetrator to the target location. In other embodiments, the blood vessel or other body lumen is blocked at spaced-apart first and second locations and a quantity of the substance is introduced into the closed-off body lumen between the blocked first and second locations. The substance then diffuses into or through the wall of the vessel or body conduit to reach the target location.Type: ApplicationFiled: December 27, 2011Publication date: July 5, 2012Applicant: MEDTRONIC VASCULAR, INC.Inventors: J. Christopher Flaherty, Joshua Makower, Philip C. Evard, Patrick E. Macaulay, Jason B. Whitt, Robert C. Colloton, K. Angela Macfarlane
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Patent number: 7966057Abstract: Electro-anatomically navigated catheters (e.g., mapping catheters, tissue penetrating catheters, delivery catheters and/or sheaths) and associated methods whereby devices or substances may be delivered to specific locations within a patient's body and/or penetration tracts or passageways are formed at specific locations between anatomical structures. The catheters are equipped with sensors and a sensing field is created around the body of the patient. The sensor-equipped catheters are then inserted into the patient's body and the position of the catheter-mounted sensor(s) is/are observed on a display representing the sensing field. Apparatus may be included for propelling the catheter(s) to specific locations and/or specific rotation orientations, within the patient's body.Type: GrantFiled: February 6, 2002Date of Patent: June 21, 2011Assignee: Medtronic Vascular, Inc.Inventors: Patrick E. Macaulay, Theodore C. Lamson, Joshua Makower, Isaac Han Joon Kim, Brian R. Beckey
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Publication number: 20110098805Abstract: Delivery devices and methods for percutaneously delivering a prosthetic valve to the heart of a patient. These prosthetic valves may be configured to provide complimentary features that promote optimal placement of the prosthetic valve in a native heart valve, such as the aortic valve, mitral valve, pulmonic valve, and/or tricuspid valve. The delivery device includes a release sheath assembly housed within an outer delivery sheath. A release sheath component of the assembly captures a portion of the prosthetic valve to the delivery device, and effectuates complete release of the prosthetic valve with retraction of the outer sheath.Type: ApplicationFiled: August 27, 2010Publication date: April 28, 2011Inventors: Joshua Dwork, Patrick E. Macaulay, Gianfranco M. Pellegrini, Finn O. Rinne, Richard Spork, Don Huy Tran, Nathan B. Wiemeyer
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Publication number: 20100324471Abstract: A transvascular system for delivering a drug to a tissue region from a blood vessel includes a catheter having a distal portion with puncturing, orientation, drug delivery, and imaging elements. The puncturing element is deployable for penetrating the vessel wall to access the tissue region. The orientation element has a predetermined relationship with the puncturing element, the imaging element detecting the location of the orientation element with respect to the tissue region to orient the puncturing element. The catheter is percutaneously introduced into the vessel, the puncturing element is oriented towards the tissue region, the puncturing element is deployed to access the tissue region, and the drug is delivered to the tissue region. An ablation device may also be deployed to create a cavity or fluid reservoir in the tissue region for receiving the drug therein, or an indwelling catheter may be advanced into and left in the tissue region.Type: ApplicationFiled: March 1, 2010Publication date: December 23, 2010Applicant: Medtronic Vascular, Inc.Inventors: J. Christopher Flaherty, Joshua Makower, Philip Evard, Patrick E. MacAulay, Jason B. Whitt, Robert C. Colloton, K. Angela Macfarlane
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Publication number: 20090287290Abstract: A delivery system for delivering a stented prosthetic heart valve to a lumen of a patient, the delivery system including a tubular body having a proximal end, a distal end, and a base portion with a plurality of extending elements, wherein each of the extending elements is engageable with a portion of a stent of a prosthetic heart valve. The delivery system further includes a sleeve having an inner area. The sheath is longitudinally moveable relative to the base portion from a first position where the inner area of the sleeve at least partially covers the extending elements of the base portion to a second position where the extending elements are not positioned within the inner area of the sleeve.Type: ApplicationFiled: January 22, 2009Publication date: November 19, 2009Applicant: Medtronic, Inc.Inventors: Patrick E. Macaulay, Robert J. Murray, Trevor Greenan, Timothy R. Ryan, Charles Tabor, Matthew J. Birdsall, Gianfranco Pellegrini
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Publication number: 20090275956Abstract: This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.Type: ApplicationFiled: April 30, 2009Publication date: November 5, 2009Applicant: Medtronic, Inc.Inventors: John E. Burnes, Kenneth C. Gardeski, Ruth N. Klepfer, Patrick E. Macaulay, Mary M. Morris, Avram Scheiner
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Publication number: 20090276022Abstract: This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.Type: ApplicationFiled: April 30, 2009Publication date: November 5, 2009Applicant: Medtronic , Inc.Inventors: John E. Burnes, Kenneth C. Gardeski, Ruth N. Klepfer, Patrick E. Macaulay, Mary M. Morris, Avram Scheiner
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Publication number: 20090259174Abstract: Methods and catheter devices/systems for removing some or all of the lipid core material from vulnerable plaque and/or for introducing one or more therapeutic substance into vulnerable plaque. The vulnerable plaque may be entered by a penetrator that is advanced into the vulnerable plaque from a catheter device that incorporates an on-board imaging, sensing or vulnerable plaque locating apparatus.Type: ApplicationFiled: April 15, 2008Publication date: October 15, 2009Applicant: Medtronic Vascular, Inc.Inventors: Michele Silver, Patrick E. Macaulay
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Patent number: 7303571Abstract: Methods and apparatus for occluding blood flow within a blood vessel. In a first series of embodiments, the present invention comprises a plurality of embolic devices deployable through the lumen of a conventional catheter such that when deployed, said embolic devices remain resident and occlude blood flow at a specific site within the lumen of the blood vessel. Such embolic devices comprise either mechanical embolic devices that become embedded within or compress against the lumen of the vessel or chemical vaso-occlusive agents that seal off blood flow at a given site. A second embodiment of the present invention comprises utilization of a vacuum/cauterizing device capable of sucking in the lumen of the vessel about the device to maintain the vessel in a closed condition where there is then applied a sufficient amount of energy to cause the tissue collapsed about the device to denature into a closure.Type: GrantFiled: August 29, 2003Date of Patent: December 4, 2007Assignee: Medtronic Vascular, Inc.Inventors: Joshua Makower, J. C. Flaherty, Timothy R. Machold, Jason B. Whitt, Philip C. Evard, Patrick E. Macaulay, John T. Garibotto, Marc Jensen
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Patent number: 7094230Abstract: An implantable reservoir device (400) including an enclosed membrane (408) on an expandable frame (402) that defines a reservoir (410) and includes a porous region (418). The reservoir device (400) may be deployed and expanded within a blood vessel, and may be filled in situ or prefilled with a drug that passes through the porous region (418). Alternatively, a pair of expandable endovascular blockers (500) may be used to isolate a section of a blood vessel which may be filled with a drug that may be absorbed by the surrounding tissue.Type: GrantFiled: December 16, 2003Date of Patent: August 22, 2006Assignee: Medtronic Vascular, Inc.Inventors: J. Christopher Flaherty, Joshua Makower, Philip C. Evard, Patrick E. MacAulay, Jason B. Whitt, Robert C. Colloton, K. Angela Macfarlane
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Publication number: 20040147837Abstract: Electro-anatomically navigated catheters (e.g., mapping catheters, tissue penetrating catheters, delivery catheters and/or sheaths) and associated methods whereby devices or substances may be delivered to specific locations within a patient's body and/or penetration tracts or passageways are formed at specific locations between anatomical structures. The catheters are equipped with sensors and a sensing field is created around the body of the patient. The sensor-equipped catheters are then inserted into the patient's body and the position of the catheter-mounted sensor(s) is/are observed on a display representing the sensing field. Apparatus may be included for propelling the catheter(s) to specific locations and/or specific rotation orientations, within the patient's body.Type: ApplicationFiled: March 12, 2004Publication date: July 29, 2004Inventors: Patrick E Macaulay, Theodore C. Lamson, Joshua Makower, Isaac Han Joon Kim, Brian R. Beckey
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Publication number: 20040133154Abstract: A transvascular system (10) for delivering a drug to a tissue region from a blood vessel, such as a coronary vein, includes a catheter (12) having a distal portion (26) with puncturing (14), orientation (16), drug delivery (62), and imaging elements (18). The puncturing element (14) is deployable for penetrating the vessel wall to access the tissue region. The orientation element (16), e.g. a “cage” including a plurality of struts (38)(40) and/or a radiopaque marker, has a predetermined relationship with the puncturing element (14), the imaging element (18) detecting the location of the orientation element (16) with respect to the tissue region to orient the puncturing element. The catheter (12) is percutaneously introducing into the vessel, the puncturing element (14) is oriented towards the tissue region, the puncturing element (14) is deployed to access the tissue region, and the drug is delivered to the tissue region.Type: ApplicationFiled: December 16, 2003Publication date: July 8, 2004Inventors: J. Christopher Flaherty, Joshua Makower, Philip C. Evard, Patrick E. MacAulay, Jason B. Whitt, Robert C. Colloton, K. Angela MacFarlane
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Publication number: 20040098030Abstract: Methods and apparatus for occluding blood flow within a blood vessel. In a first series of embodiments, the present invention comprises a plurality of embolic devices deployable through the lumen of a conventional catheter such that when deployed, said embolic devices remain resident and occlude blood flow at a specific site within the lumen of the blood vessel. Such embolic devices comprise either mechanical embolic devices that become embedded within or compress against the lumen of the vessel or chemical vaso-occlusive agents that seal off blood flow at a given site. A second embodiment of the present invention comprises utilization of a vacuum/cauterizing device capable of sucking in the lumen of the vessel about the device to maintain the vessel in a closed condition where there is then applied a sufficient amount of energy to cause the tissue collapsed about the device to denature into a closure.Type: ApplicationFiled: August 29, 2003Publication date: May 20, 2004Applicant: Trans Vascular, Inc.Inventors: Joshua Makower, J. Christopher Flaherty, Timothy R. Machold, Jason B. Whitt, Philip C. Evard, Patrick E. Macaulay, John T. Garibotto, Marc Jensen
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Patent number: 6685648Abstract: A method is provided for delivering a drug to a selected tissue region within a patient's body with a catheter having a deployable puncturing element, a drug delivery element and an orientation element on a distal portion thereof. The distal portion of the catheter is percutaneously introduced into a blood vessel, and directed endovascularly to a vessel location adjacent to the selected tissue region. The puncturing element is oriented towards the selected tissue region, and deployed to access the selected tissue region. A drug is delivered with the drug delivery element to the selected tissue region.Type: GrantFiled: April 3, 2001Date of Patent: February 3, 2004Assignee: Transvascular, Inc.Inventors: J. Christopher Flaherty, Joshua Makower, Philip C. Evard, Patrick E. MacAulay, Jason B. Whitt, Robert C. Colloton, K. Angela Macfarlane
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Patent number: 6638293Abstract: This invention is methods and apparatus for occluding blood flow within a blood vessel (22). In a first series of embodiments, the present invention comprises a plurality of embolic devices (16) deployable through the lumen (12) of a conventional catheter (10) such that when deployed, said embolic devices (16) remain resident and occlude blood flow at a specific site within the lumen of the blood vessel (22). Such embolic devices (16) comprise either mechanical embolic devices that become embedded within or compress against the lumen of the vessel or chemical vaso occlusive agents that seal off blood flow at a given site. A second embodiment of the present invention comprises utilization of a vacuum/cauterizing device capable of sucking in the lumen of the vessel about the device to maintain the vessel in a closed condition where there is then applied a sufficient amount of energy to cause the tissue collapsed about the device to denature into a closure.Type: GrantFiled: January 21, 1999Date of Patent: October 28, 2003Assignee: TransVascular, Inc.Inventors: Joshua Makower, J. Christopher Flaherty, Timothy R. Machold, Jason B. Whitt, Philip C. Evard, Patrick E. Macaulay, John T. Garibotto, Marc Jensen
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Patent number: 6616675Abstract: Anastomotic connectors and apparatus for forming and/or maintaining connections between openings formed in anatomical structures, such as blood vessels. The apparatus is initially deployed in a first configuration which is sufficiently compact to be delivered through the lumen of a catheter or cannula. Thereafter, the device is expanded to a second configuration whereby it engages the anatomical structures and forms or maintains the desired connection between openings in the anatomical structures.Type: GrantFiled: March 17, 1999Date of Patent: September 9, 2003Assignee: Transvascular, Inc.Inventors: Philip C. Evard, Joshua Makower, J. C. Flaherty, Timothy R. Machold, Jason B. Whitt, Patrick E. Macaulay, John T. Garibotto, Alex T. Roth
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Patent number: 6544230Abstract: A system of catheter devices and methods for forming channels or passageways between a luminal anatomical structure (e.g., a blood vessel) and a target location (e.g., another blood vessel, an organ, a mass of tissue, etc.) for the purpose of rerouting blood flow or for delivering a substance or instrument, etc. to the target location.Type: GrantFiled: March 31, 1999Date of Patent: April 8, 2003Assignee: TransVascular, Inc.Inventors: J. Christopher Flaherty, Jason B. Whitt, Patrick E. Macaulay, David R. Tholfsen, John T. Garibotto, Philip C. Evard, Joshua Makower
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Publication number: 20020002349Abstract: A transvascular system (10) for delivering a drug to a tissue region from a blood vessel, such as a coronary vein, includes a catheter (12) having a distal portion (26) with puncturing (14), orientation (16), drug delivery (62), and imaging elements (18). The puncturing element (14) is deployable for penetrating the vessel wall to access the tissue region. The orientation element (16), e.g. a “cage” including a plurality of struts (38) (40) and/or a radiopaque marker, has a predetermined relationship with the puncturing element (14), the imaging element (18) detecting the location of the orientation element (16) with respect to the tissue region to orient the puncturing element. The catheter (12) is percutaneously introducing into the vessel, the puncturing element (14) is oriented towards the tissue region, the puncturing element (14) is deployed to access the tissue region, and the drug is delivered to the tissue region.Type: ApplicationFiled: April 3, 2001Publication date: January 3, 2002Applicant: Transvascular, Inc.Inventors: J. Christopher Flaherty, Joshua Makower, Philip C. Evard, Patrick E. MacAulay, Jason B. Whitt, Robert C. Colloton, K. Angela Macfarlane