Patents by Inventor Patrick F. Kiser
Patrick F. Kiser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10350160Abstract: The present technology provides intravaginal devices designed to deliver lubricants to the vagina for a sustained period of time. The intravaginal devices include a first segment comprising an outer surface and a lumen containing a lubricant, wherein the first segment is configured to deliver the contents of the lumen to the outer surface, and the first segment comprises a polymer selected from the group consisting of a hydrophilic, semi-permeable elastomer and a hydrophobic elastomer. The lubricant may be an aqueous lubricant. The present technology further provides an intravaginal device including a solid first segment that includes a hydrophilic semi-permeable elastomer, an outer surface and an aqueous lubricant, wherein the first segment is configured to deliver the aqueous lubricant to the outer surface.Type: GrantFiled: October 27, 2017Date of Patent: July 16, 2019Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION, THEInventors: Patrick F. Kiser, R. Tyler McCabe, Margaret N. Kiser, Theodore Henry Albright
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Publication number: 20180104182Abstract: The present technology provides intravaginal devices designed to deliver lubricants to the vagina for a sustained period of time. The intravaginal devices include a first segment comprising an outer surface and a lumen containing a lubricant, wherein the first segment is configured to deliver the contents of the lumen to the outer surface, and the first segment comprises a polymer selected from the group consisting of a hydrophilic, semi-permeable elastomer and a hydrophobic elastomer. The lubricant may be an aqueous lubricant. The present technology further provides an intravaginal device including a solid first segment that includes a hydrophilic semi-permeable elastomer, an outer surface and an aqueous lubricant, wherein the first segment is configured to deliver the aqueous lubricant to the outer surface.Type: ApplicationFiled: October 27, 2017Publication date: April 19, 2018Inventors: Patrick F. Kiser, R. Tyler McCabe, Margaret N. Kiser, Theodore Henry Albright
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Publication number: 20170273899Abstract: The present technology provides intravaginal devices designed to deliver lubricants to the vagina for a sustained period of time. The intravaginal devices include a first segment comprising an outer surface and a lumen containing a lubricant, wherein the first segment is configured to deliver the contents of the lumen to the outer surface, and the first segment comprises a polymer selected from the group consisting of a hydrophilic, semi-permeable elastomer and a hydrophobic elastomer. The lubricant may be an aqueous lubricant. The present technology further provides an intravaginal device including a solid first segment that includes a hydrophilic semi-permeable elastomer, an outer surface and an aqueous lubricant, wherein the first segment is configured to deliver the aqueous lubricant to the outer surface.Type: ApplicationFiled: April 18, 2017Publication date: September 28, 2017Inventors: Patrick F. Kiser, R. Tyler McCabe, Margaret N. Kiser, Theodore Henry Albright
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Patent number: 9642795Abstract: The present technology provides intravaginal devices designed to deliver lubricants to the vagina for a sustained period of time. The intravaginal devices include a first segment comprising an outer surface and a lumen containing a lubricant, wherein the first segment is configured to deliver the contents of the lumen to the outer surface, and the first segment comprises a polymer selected from the group consisting of a hydrophilic, semi-permeable elastomer and a hydrophobic elastomer. The lubricant may be an aqueous lubricant. The present technology further provides an intravaginal device including a solid first segment that includes a hydrophilic semi-permeable elastomer, an outer surface and an aqueous lubricant, wherein the first segment is configured to deliver the aqueous lubricant to the outer surface.Type: GrantFiled: January 4, 2016Date of Patent: May 9, 2017Assignee: The University of Utah Research FoundationInventors: Patrick F. Kiser, R. Tyler McCabe, Margaret N. Kiser, Theodore Henry Albright
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Publication number: 20160113866Abstract: The present technology provides intravaginal devices designed to deliver lubricants to the vagina for a sustained period of time. The intravaginal devices include a first segment comprising an outer surface and a lumen containing a lubricant, wherein the first segment is configured to deliver the contents of the lumen to the outer surface, and the first segment comprises a polymer selected from the group consisting of a hydrophilic, semi-permeable elastomer and a hydrophobic elastomer. The lubricant may be an aqueous lubricant. The present technology further provides an intravaginal device including a solid first segment that includes a hydrophilic semi-permeable elastomer, an outer surface and an aqueous lubricant, wherein the first segment is configured to deliver the aqueous lubricant to the outer surface.Type: ApplicationFiled: January 4, 2016Publication date: April 28, 2016Inventors: Patrick F. Kiser, R. Tyler McCabe, Margaret N. Kiser, Theodore Henry Albright
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Patent number: 9226894Abstract: The present technology provides intravaginal devices designed to deliver lubricants to the vagina for a sustained period of time. The intravaginal devices include a first segment comprising an outer surface and a lumen containing a lubricant, wherein the first segment is configured to deliver the contents of the lumen to the outer surface, and the first segment comprises a polymer selected from the group consisting of a hydrophilic, semi-permeable elastomer and a hydrophobic elastomer. The lubricant may be an aqueous lubricant. The present technology further provides an intravaginal device including a solid first segment that includes a hydrophilic semi-permeable elastomer, an outer surface and an aqueous lubricant, wherein the first segment is configured to deliver the aqueous lubricant to the outer surface.Type: GrantFiled: May 11, 2015Date of Patent: January 5, 2016Assignee: THE UNIVERSITY OF UTAH RESEARCH FOUNDATIONInventors: Patrick F. Kiser, R. Tyler McCabe, Margaret N. Kiser, Theodore Henry Albright
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Publication number: 20150320675Abstract: In one aspect, the invention relates to controlled-release devices and methods of using same, alone or in combination with other agents, to deliver pharmaceutical agents, and more particularly to deliver birth control agent, fertility agents, hormone replacement agents, cervical ripening agents, agents to prevent a sexually transmitted disease, agents to treat a sexually transmitted disease, biologics, agents to treat a mucosal infection, agents to treat uterine fibroids, agents to treat reproductive cancers, agents to treat nausea gravidarum, and/or agents to treat endometriosis. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: ApplicationFiled: January 17, 2014Publication date: November 12, 2015Inventors: Patrick F. Kiser, Rachna A. Rastogi
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Publication number: 20150238415Abstract: The present technology provides intravaginal devices designed to deliver lubricants to the vagina for a sustained period of time. The intravaginal devices include a first segment comprising an outer surface and a lumen containing a lubricant, wherein the first segment is configured to deliver the contents of the lumen to the outer surface, and the first segment comprises a polymer selected from the group consisting of a hydrophilic, semi-permeable elastomer and a hydrophobic elastomer. The lubricant may be an aqueous lubricant. The present technology further provides an intravaginal device including a solid first segment that includes a hydrophilic semi-permeable elastomer, an outer surface and an aqueous lubricant, wherein the first segment is configured to deliver the aqueous lubricant to the outer surface.Type: ApplicationFiled: May 11, 2015Publication date: August 27, 2015Inventors: Patrick F. Kiser, R. Tyler McCabe, Margaret N. Kiser, Theodore Henry Albright
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Patent number: 9078813Abstract: The present technology provides intravaginal devices designed to deliver lubricants to the vagina for a sustained period of time. The intravaginal devices include a first segment comprising an outer surface and a lumen containing a lubricant, wherein the first segment is configured to deliver the contents of the lumen to the outer surface, and the first segment comprises a polymer selected from the group consisting of a hydrophilic, semi-permeable elastomer and a hydrophobic elastomer. The lubricant may be an aqueous lubricant. The present technology further provides an intravaginal device including a solid first segment that includes a hydrophilic semi-permeable elastomer, an outer surface and an aqueous lubricant, wherein the first segment is configured to deliver the aqueous lubricant to the outer surface.Type: GrantFiled: November 11, 2011Date of Patent: July 14, 2015Assignee: THE UNIVERSITY OF UTAH RESEARCH FOUNDATIONInventors: Patrick F. Kiser, R. Tyler McCabe, Margaret N. Kiser, Theodore Henry Albright
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Publication number: 20140209100Abstract: Intravaginal drug delivery devices, including intravaginal rings, are provided herein. The devices include a reservoir of at least one vaginally administrable drug wherein the reservoir is surrounded at least in part by a hydrophilic elastomer. The devices are capable of exhibiting a substantially zero order release profile of drug over extended periods of time. Also disclosed are methods for making the devices and methods of using the devices to prevent or treat a biological condition.Type: ApplicationFiled: July 20, 2012Publication date: July 31, 2014Inventors: Patrick F. Kiser, Todd Joseph Johnson, Justin Thomas Clark, Namdev Shelk, Rachna Rastogi
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Patent number: 8747870Abstract: Described herein are polymeric compositions that comprise at least one polymer residue and at least one crosslinking moiety, wherein the polymer residue is crosslinked by the crosslinking moiety and wherein the crosslinking moiety is formed from a reaction between a boronic acid moiety and a hydroxamic acid moiety. Also, described are methods of making and using such polymeric compositions.Type: GrantFiled: January 16, 2013Date of Patent: June 10, 2014Assignee: University of Utah Research FoundationInventors: Kavita Gupta, Meredith R. Clark, Patrick F. Kiser, Julie I. Jay
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Publication number: 20140074067Abstract: The present technology provides intravaginal devices designed to deliver lubricants to the vagina for a sustained period of time. The intravaginal devices include a first segment comprising an outer surface and a lumen containing a lubricant, wherein the first segment is configured to deliver the contents of the lumen to the outer surface, and the first segment comprises a polymer selected from the group consisting of a hydrophilic, semi-permeable elastomer and a hydrophobic elastomer. The lubricant may be an aqueous lubricant. The present technology further provides an intravaginal device including a solid first segment that includes a hydrophilic semi-permeable elastomer, an outer surface and an aqueous lubricant, wherein the first segment is configured to deliver the aqueous lubricant to the outer surface.Type: ApplicationFiled: November 11, 2011Publication date: March 13, 2014Inventors: Patrick F. Kiser, R. Tyler McCabe, Margaret N. Kiser, Theodore Henry Albright
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Publication number: 20130220337Abstract: The present technology provides intravaginal devices designed to intravaginally deliver difficult to formulate water-soluble molecules and macromolecules for a sustained period of time. The devices include a chamber having at least one orifice and containing a sustained-release formulation. Such formulations include a water-swellable polymer and an intravaginally administrable substance. Methods of making and using the devices are also provided.Type: ApplicationFiled: August 19, 2011Publication date: August 29, 2013Inventors: Patrick F. Kiser, Vlad G. O'mel, Leland J. Prather, Festo Damian
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Publication number: 20130164249Abstract: Described herein are methods of inhibiting the activity of a virus or a bacterium comprising contacting a virus or bacterium with a polymer functionalized with at least one boronic acid moiety. Also described are methods of treatment using such functionalized polymers.Type: ApplicationFiled: February 22, 2013Publication date: June 27, 2013Inventors: Patrick F. Kiser, Julie I. Jay, Meredith C. Roberts Clarck
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Publication number: 20110059040Abstract: Described herein are methods of inhibiting the activity of a virus or a bacterium comprising contacting a virus or bacterium with a polymer functionalized with at least one boronic acid moiety. Also described are methods of treatment using such functionalized polymers.Type: ApplicationFiled: June 26, 2008Publication date: March 10, 2011Inventors: Patrick F. Kiser, Julie I. Jay, Meredith C. Roberts
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Publication number: 20110045076Abstract: Intravaginal drug delivery devices, including intravaginal rings, are provided herein. The devices comprise a polyether urethane composition and a pharmaceutically effective amount of at least one vaginally administrable drug homogeneously distributed throughout the polyether urethane. The devices are capable of exhibiting a substantially zero order release profile of drug over extended periods of time. Also disclosed are methods for making the devices and methods of using the devices to prevent or treat a biological condition.Type: ApplicationFiled: January 23, 2009Publication date: February 24, 2011Inventors: Patrick F. Kiser, Kavita Gupta
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Publication number: 20100166826Abstract: The present disclosure relates to biodegradable intravaginal rings for the delivery of therapeutic or prophylactic agent, inter alia, antiviral agents. The present disclosure further relates to biodegradable polyurethanes which will allow therapeutic/prophylactic agents to be released in a controlled manner that will not degrade when in use, but will degrade upon disposal.Type: ApplicationFiled: January 22, 2008Publication date: July 1, 2010Applicant: University of Uath Research FoundationInventors: Patrick F. Kiser, Patrick Tresco, Mark Mitchnick, Kavita Gupta, Hyder Aliyar
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Publication number: 20090220607Abstract: Described herein are polymeric compositions having a polymer residue and a crosslinker residue, wherein the polymer residue is bonded to the crosslinker residue with a moiety formed from a cycloaddition reaction. Also, described are methods of making and using such polymeric compositions.Type: ApplicationFiled: September 11, 2006Publication date: September 3, 2009Inventors: Patrick F. Kiser, Meredith C. Roberts
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Publication number: 20080140185Abstract: The compositions disclosed herein include biodegradable elastomers that provide a material for. medical purposes. They may further provide a drug delivery system for the treatment of a wide variety of medical conditions. In particular, the compositions provide biodegradable elastomers composed of a pre-polymeric block, a degradable sequence and a bis-functional linker. The usefulness of the present invention is that it provides a biodegradable elastomer for use with medical devices.Type: ApplicationFiled: April 15, 2005Publication date: June 12, 2008Inventors: Patrick F. Kiser, Patrick Tresco
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Patent number: 6582726Abstract: A method for performing chemical synthesis includes the steps of providing a solid support having cross links, a first set of cleavable links within the cross links, and a second set of cleavable links having sites on which to perform chemistry. A first chemical is coupled to the chemistry sites, and the first chemical is reacted with a second chemical to produce a reaction product. The links are cleaved to remove the cross links and to cleave the reaction product from the solid support.Type: GrantFiled: June 21, 2000Date of Patent: June 24, 2003Assignee: SmithKline Beecham CorporationInventors: H. Mario Geysen, Patrick F. Kiser