Abstract: Bispecific antibodies which comprise antigen-binding regions binding to two different epitopes of human epidermal growth factor receptor 2 (HER2), and related antibody-based compositions and molecules, are disclosed. Pharmaceutical compositions comprising the antibodies and methods of preparing and using the antibodies are also disclosed.

Abstract: A method for operating a wireless field-device network, comprising: wirelessly transmitting a process variable and an expected remaining running time from each field device to the other field devices within a field-device network so that in each field device the process variable and the expected remaining running time of the other field devices of the field-device network are stored; activating a second radio module of that field device which has the highest expected remaining running time, and deactivating the second radio modules of the other field devices within the field-device network; wirelessly transmitting the process variables of all field devices of the field-device network stored in the active field device, or at least a subset of the stored process variables, to the superordinate unit, which is not part of the field-device network, by means of the second radio module of the active field device.

Abstract: An apparatus and method of Black Soldier Fly breeding are provided. The method includes emitting a lure light to lure Black Soldier Flies into an interior space of a fly enclosure, emitting a mating light to induce Black Soldier Flies in the interior space to mate, and illuminating the interior space to a first illuminance above an ovipositing illuminance threshold and below a mating inducing illuminance threshold. The lure light has a first wavelength range that attracts recently hatched Black Soldier Flies into the fly enclosure through one or more lure ports formed in the fly enclosure. The mating light has a second wavelength range that induces Black Soldier Flies to mate. The method may also include illuminating the interior space to a second illuminance below the ovipositing illuminance threshold so that Black Soldier Flies in the interior space are encouraged to rest.

Abstract: A method for redirection of coolant flow is provided. The method includes an identifying step that identifies a hot spot on an exterior surface of a body of a component of a turbine system. A first parameter of the component indicates that a temperature of the exterior surface in the hot spot exceeds a threshold value. Another identifying step identifies a cool spot on the exterior surface. A second parameter of the component indicates that the temperature of the exterior surface in the cool spot is below the threshold value. A reconfiguring step reconfigures a plurality of cooling passages of the component to direct a portion of a coolant from the cool spot to the hot spot.

Abstract: The present invention relates to reactive hotmelt adhesive compositions comprising, based on the total weight of the composition, a) 3 wt % to 49 wt % of at least one alpha-silane-terminated organic polymer; b) 1 wt % to less than 20 wt %, preferably 1 wt % to 10 wt %, of at least one acrylate resin-based polymer; c) 1 wt % to 20 wt %, preferably 1 wt % to 10 wt %, of at least one chemical compound which is liquid at least at 100° C. and in which at least at 150° C. the at least one acrylate resin-based polymer dissolves; d) 0.001 wt % to 5 wt %, preferably 0.001 wt % to 2 wt %, of at least one oligomeric silane comprising one or more amino groups. The invention additionally relates to processes for producing them and to a process for surface lamination using the composition.

Abstract: The invention relates to a reactive single-component adhesive composition which is liquid at room temperature and which has 3 wt. % to 90 wt. % of at least one alpha-silane-terminated organic polymer, 0 wt. % to 80 wt. % of at least one silicone resin, 0.1 wt. % to 5 wt. % of at least one thermal accelerator, 0.001 wt. % to 5 wt. % of at least one low-molecular silane which has a primary or secondary amino group or a blocked amino group that is hydrogenated in order to form the primary or secondary amino group, and 0 wt. % to 85 wt. % of at least one filler. The invention additionally relates to a method for adhering two substrates using the aforementioned adhesive composition and to a system adhered in such a manner.

Abstract: The present invention relates to reactive hotmelt adhesive compositions comprising, based on the total weight of the composition, a) 3 wt % to 49 wt % of at least one alpha-silane-terminated organic polymer; b) 1 wt % to less than 20 wt %, preferably 1 wt % to 10 wt %, of at least one acrylate resin-based polymer; c) 1 wt % to 20 wt %, preferably 1 wt % to 10 wt %, of at least one chemical compound which is liquid at least at 100° C. and in which at least at 150° C. the at least one acrylate resin-based polymer dissolves; d) 0.001 wt % to 5 wt %, preferably 0.001 wt % to 1 wt %, of at least one low molecular mass silane which comprises a primary or secondary amino group or a blocked amino group which hydrolyses to the primary or secondary amino group. The invention additionally relates to processes for producing them and to a process for surface lamination using the composition.

Abstract: Disclosed is a bottle for containing a beverage which has plastic body. The bottle includes a bottom surface having a non-sliding element located to be in contact with a surface when the bottle is in the upright position. In addition or alternately, the bottle includes a neck portion which has at least two spaced apart circumferential ribs. Preferably, each of the ribs is disposed normal to a vertical axis of the bottle in its upright position. In another embodiment of the invention, the ribs are continuous along the exterior of the neck.

Abstract: Disclosed is a bottle for containing a beverage which has plastic body. The bottle includes a bottom surface having a non-sliding element located to be in contact with a surface when the bottle is in the upright position. In addition or alternately, the bottle includes a neck portion which has at least two spaced apart circumferential ribs. Preferably, each of the ribs is disposed normal to a vertical axis of the bottle in its upright position. In another embodiment of the invention, the ribs are continuous along the exterior of the neck.

Abstract: A seat track system for a seat of a vehicle includes at least one seat track having a lower track member adapted to be fixed to a vehicle structure and an upper track member adapted to be connected to a seat and moveable relative to the lower track member. The seat track system also includes a manual positive engagement locking system cooperating with the at least one seat track to allow longitudinal adjustment of the upper track member relative to the lower track member and to positively engage the at least one seat track such that a locking element does extend through the locking plate but does not extend below the lower track member.

Abstract: A seat track system for a seat of a vehicle includes at least one seat track having a lower track member adapted to be fixed to a vehicle structure and an upper track member adapted to be connected to a seat and moveable relative to the lower track member. The seat track system also includes a manual positive engagement locking system cooperating with the at least one seat track to allow longitudinal adjustment of the upper track member relative to the lower track member and to positively engage the at least one seat track such that a locking element does extend through the locking plate but does not extend below the lower track member.

Abstract: Disclosed is a bottle for containing a beverage which has plastic body. The bottle includes a bottom surface having a non-sliding element located to be in contact with a surface when the bottle is in the upright position. In addition or alternately, the bottle includes a neck portion which has at least two spaced apart circumferential ribs. Preferably, each of the ribs is disposed normal to a vertical axis of the bottle in its upright position. In another embodiment of the invention, the ribs are continuous along the exterior of the neck.

Abstract: A beach cart having a main compartment with a front opening. A pair of doors hingedly connected to the compartment may be closed to block the opening or opened to a position in which they cooperate with a pair of wide wheels to support the compartment in an upright position. The cart is adapted to support various accessories such as an umbrella, a chair, and cooler cups.

Abstract: An illuminated sign display is mounted on a truck or trailer sidewall. The display includes a four sided frame with one of the frame sides being hinged so that it can be opened to receive an advertising sheet, between a front clear plastic sheet for protecting the advertising sheet, and a rear white translucent sheet. The display also includes a white metal back sheet adjacent the truck wall and an illumination device mounted between the white metal back sheet and the white translucent sheet in a chamber formed between the two.

Abstract: In a liquid level contents indicator for a vehicle hydraulic system of the float-operated electric switch type manually operable mechanism for testing the circuit comprises a push-button located in an end closure cap for a reservoir and the push-button acts on contacts of the electric circuit through a resilient diaphragm which also acts as a return spring for the push-button and provides a seal between the push button and the cap.

Abstract: A vehicle load sensing arrangement for use with a vehicle braking system comprises an input member operating in a first bore and being subjected to the force of a road spring, a spring, such as a robust helical coil spring, subjecting the input member to a force in opposition to the road spring force, a valve having a valve member in a second bore which has a cross-sectional area smaller than the first bore, the valve member and input member being substantially in alignment, and an elastomeric member located between the input member and the valve member. The arrangement is such that only a proportion of the road spring force applied to the input member in excess of the coil spring force is transmitted by the elastomeric member to the valve member, the remainder of that excess force being transmitted to the sprung part of the vehicle.

Abstract: A power assisted pedal assembly comprises a brake pedal pivotally connected at one end to a lever which is pivotal about a fixed point, the brake pedal having a connection intermediate its ends with an actuating member of a master cylinder to apply an operating force to the actuating member, and a power assistor operable in response to movement of the brake pedal to apply an assisting force to the brake pedal. The power assistor has a force-transmitting member which is separate from the actuating member and which is in force-transmitting engagement with the lever on or close to the line of action of the force applied to the actuating member by the brake pedal. The brake pedal and the lever pivot about the fixed point when the power assistor is operative and the pedal pivots about a point intermediate the fixed point and the connection between the lever and the actuating member upon failure of the power assistor.

Abstract: A brake actuating assembly for actuating a master cylinder having a power assistor comprises a brake pedal pivotable about a pivot point at one end and connected at a point intermediate its ends to an actuating member of the master cylinder, movement of the actuator member also actuating the power assistor, the pivot point being connected to a piston of a fluid motor operable in response to the operating pressure of the power assistor the arrangement being such that in normal operation the pressure of the power assistor actuates the piston to hold the pivot point in a fixed position but upon failure of the power assisting means the pivot point is moved to vary the pedal ratio, to permit the master cylinder to be operated without power assistance.