Patents by Inventor Patrick H. Griffin

Patrick H. Griffin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING SHORT BOWEL SYNDROME AND/OR HIGH OUTPUT OSTOMY
    Publication number: 20230331859
    Abstract: The present invention provides methods for treating short bowel syndrome and/or high output ostomy. The invention comprises administering to a patient in need a long-acting GLP-1 receptor agonist. In various embodiments, the method reduces ostomy output, reduces requirement for parenteral nutrition, and/or ameliorates acute intestinal failure.
    Type: Application
    Filed: May 2, 2023
    Publication date: October 19, 2023
    Inventors: Patrick H. GRIFFIN, Nir BARAK, Sireesh APPAJOSYULA
  • LARAZOTIDE DERIVATIVES COMPRISING D-AMINO ACIDS
    Publication number: 20230218706
    Abstract: The present invention provides compositions comprising an effective amount of a peptide having the amino acid sequence Gly-Gly-(d)Val-(d)Leu-(d)Val-(d)Gln-(d)Pro-Gly (SEQ ID NO: 6) to promote tight junction integrity, or a pharmaceutically acceptable salt thereof, and a pharmaceutically-acceptable carrier. The present invention further provides methods of using the larazotide derivative compositions for promoting tight junction integrity in patients in need thereof.
    Type: Application
    Filed: April 15, 2021
    Publication date: July 13, 2023
    Inventors: Jay P. MADAN, Balasingham RADHAKRISHNAN, Sandeep LAUMAS, Christopher PRIOR, Anthony BLIKSLAGER, Patrick H. GRIFFIN, Nir BARAK, Sireesh APPAJOSYULA
  • COMPOSITIONS AND METHODS FOR TREATING ULCERATIVE COLITIS
    Publication number: 20220265684
    Abstract: The invention, in various aspects and embodiments, provides compositions and methods for treating or managing ulcerative colitis (UC) (including mild or moderate UC), including intestinal and extraintestinal symptoms, including but not limited to arthritis. The compositions and methods in various embodiments relate to oral administration of pharmaceutical compositions that comprise an effective amount of one or more agents that forms at least one 4-APAA compound by azo reduction in the colon. In various embodiments, active agent is available for local action in the lumen of the large intestine. Further, as described herein, a significant portion of the 4-APAA formed by azo reduction in the large intestine is systemically available to ameliorate extraintestinal symptoms.
    Type: Application
    Filed: August 3, 2021
    Publication date: August 25, 2022
    Inventors: Nir BARAK, Sireesh APPAJOSYULA, Patrick H. GRIFFIN
  • AGONISTS OF GUANYLATE CYCLASE AND THEIR USES
    Publication number: 20210379142
    Abstract: This invention provides a method of colonic cleansing.
    Type: Application
    Filed: February 24, 2021
    Publication date: December 9, 2021
    Inventors: Dennis RIFF, Gary S. JACOB, Kunwar SHAILUBHAI, Patrick H. GRIFFIN
  • Agonists of guanylate cyclase and their uses
    Patent number: 10967043
    Abstract: This invention provides a method of colonic cleansing.
    Type: Grant
    Filed: June 10, 2019
    Date of Patent: April 6, 2021
    Assignee: Bausch Health Ireland Limited
    Inventors: Dennis Riff, Gary S. Jacob, Kunwar Shailubhai, Patrick H. Griffin
  • AGONISTS OF GUANYLATE CYCLASE AND THEIR USES
    Publication number: 20200054709
    Abstract: This invention provides a method of colonic cleansing.
    Type: Application
    Filed: June 10, 2019
    Publication date: February 20, 2020
    Inventors: Dennis RIFF, Gary S. JACOB, Kunwar SHAILUBHAI, Patrick H. GRIFFIN
  • Agonists of guanylate cyclase and their uses
    Patent number: 10342848
    Abstract: This invention provides a method of colonic cleansing.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: July 9, 2019
    Assignee: BAUSCH HEALTH IRELAND LIMITED
    Inventors: Dennis Riff, Gary S. Jacob, Kunwar Shailubhai, Patrick H. Griffin
  • AGONISTS OF GUANYLATE CYCLASE AND THEIR USES
    Publication number: 20170143789
    Abstract: This invention provides a method of colonic cleansing.
    Type: Application
    Filed: December 16, 2016
    Publication date: May 25, 2017
    Inventors: Dennis RIFF, Gary S. JACOB, Kunwar SHAILUBHAI, Patrick H. GRIFFIN
  • Agonists of guanylate cyclase and their uses
    Patent number: 9545446
    Abstract: This invention provides a method of colonic cleansing.
    Type: Grant
    Filed: February 25, 2014
    Date of Patent: January 17, 2017
    Assignee: SYNERGY PHARMACEUTICALS, INC.
    Inventors: Dennis Riff, Gary S. Jacob, Kunwar Shailubhai, Patrick H. Griffin
  • Agonists of Guanylate Cyclase and Their Uses
    Publication number: 20140242124
    Abstract: This invention provides a method of colonic cleansing.
    Type: Application
    Filed: February 25, 2014
    Publication date: August 28, 2014
    Inventors: Dennis Riff, Gary S. Jacob, Kunwar Shailubhai, Patrick H. Griffin