Patents by Inventor Patrick H. McMinn

Patrick H. McMinn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and device for creating organotypic lumen models in a microwell plate
    Patent number: 12403477
    Abstract: A method and device of creating a lumen model in a microwell plate defining a well is provided. A rod is inserted through the well of the microwell plate and the well is filled with a polymerizable material. The material is polymerized in the well. The rod is removed from the well of the microwell plate such that the polymerized material defines a lumen.
    Type: Grant
    Filed: June 12, 2024
    Date of Patent: September 2, 2025
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: David J. Beebe, Patrick H. McMinn
  • Method and device for creating organotypic lumen models in a microwell plate
    Patent number: 12151244
    Abstract: A method and device of creating a lumen model in a microwell plate defining a well is provided. A rod is inserted through the well of the microwell plate and the well is filled with a polymerizable material. The material is polymerized in the well. The rod is removed from the well of the microwell plate such that the polymerized material defines a lumen.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: November 26, 2024
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: David J. Beebe, Patrick H. McMinn
  • Method And Device For Creating Organotypic Lumen Models In A Microwell Plate
    Publication number: 20240367174
    Abstract: A method and device of creating a lumen model in a microwell plate defining a well is provided. A rod is inserted through the well of the microwell plate and the well is filled with a polymerizable material. The material is polymerized in the well. The rod is removed from the well of the microwell plate such that the polymerized material defines a lumen.
    Type: Application
    Filed: June 12, 2024
    Publication date: November 7, 2024
    Inventors: David J. Beebe, Patrick H. McMinn
  • Microfluidic Device And Method Of Assaying For Immune Cell Exhaustion Using Same
    Publication number: 20220062895
    Abstract: A microfluidic device and method of assaying for immune cell exhaustion therewith are provided. The microfluidic device includes a moveable rod positioned across a chamber of a microfluidic device adjacent a first end thereof. Target cells are mixed into a hydrogel and the hydrogel is injected into the chamber about the moveable rod. The hydrogel is polymerized in. the chamber and the moveable rod is removed from the hydrogel so as to form a passageway in the hydrogel. The passageway is filled with a solution including immune cells. The immune cells migrate/diffuse into the hydrogel. A gradient of nutrients is formed in the chamber from. the first end to a second end of the chamber. One or more biopsies of the hydrogel may be taken at user selected location(s) of the chamber.
    Type: Application
    Filed: August 27, 2020
    Publication date: March 3, 2022
    Inventors: David J. Beebe, Patrick H. McMinn, Jose M. Ayuso, Maria Virumbra!es-Munoz
  • Method And Device For Creating Organotypic Lumen Models In A Microwell Plate
    Publication number: 20220062891
    Abstract: A method and device of creating a lumen model in a microwell plate defining a well is provided. A rod is inserted through the well of the microwell plate and the well is filled with a polymerizable material. The material is polymerized in the well. The rod is removed from the well of the microwell plate such that the polymerized material defines a lumen.
    Type: Application
    Filed: August 27, 2020
    Publication date: March 3, 2022
    Inventors: David J. Beebe, Patrick H. McMinn