Patents by Inventor Patrick Harrison
Patrick Harrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240005514Abstract: During operation, a system may obtain first and second magnetic resonance (MR) measurements associated with a biological lifeform, where the first and second MR measurements were acquired while the biological lifeform engaged in free breathing and/or without prospective gating based on a cardiac rhythm of the biological lifeform, and the first and second MR measurements were acquired at different times. Then, the system may dynamically determine first and second instances of one or more anatomical structures associated with the biological lifeform based at least in part on the first and second MR measurements, and a segmentation technique. Next, the system may perform a quantitative comparison of the first instance of the one or more anatomical structures and the second instance of the one or more anatomical structures, where the quantitative comparison has an uncertainty of less than a predefined value.Type: ApplicationFiled: June 29, 2023Publication date: January 4, 2024Inventors: Jeffrey H. Kaditz, Aikaterini Kotrosou, Gordon Duffley, Blake Edwin Zimmerman, Thomas Witzel, Adam Patrick Harrison
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Patent number: 11779931Abstract: Instruments, systems, and methods for measuring optical density of microbiological samples are provided. In particular, optical density instruments providing improved safety, efficiency, comfort, and convenience are provided. Such optical density instruments include a handheld portion and a base station. The optical density instruments may be used in systems and methods for measuring optical density of biological samples.Type: GrantFiled: September 9, 2021Date of Patent: October 10, 2023Assignee: bioMerieux Inc.Inventors: Perry D. Stamm, Joel Patrick Harrison, Gregory R Maes, Jeffrey Edward Price, Jack R. Hoffmann, Jr., John Kenneth Korte, Daniel Joseph Pingel, Walter J. Clynes, Sean Gregory Furman, Leonard H. Schleicher, Christopher George Kocher, Brian David Peterson, Jacky S. Yam
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Patent number: 11673141Abstract: A method, computer program product, and apparatus are provided for controlling components of a detection device. The device may detect turbidity of liquid with sensors such as a density sensor and/or nephelometric sensor. A light modulation pattern may reduce or eliminate interference in sensor readings. Readings may be performed during off cycles of an illumination light to reduce interference but to provide improved visibility of a tube. Dark and light sensor readings may be performed with an emitter respectively off or on to account for ambient light in subsequent readings. Readings from the density sensor and/or nephelometric sensor may be used to calculate McFarland values. The device may be zeroed based on an emitter level that results in a sensor reading satisfying a predetermined criterion.Type: GrantFiled: September 14, 2021Date of Patent: June 13, 2023Assignee: BIOMERIEUX, INC.Inventors: Joel Patrick Harrison, John Kenneth Korte, Jeffrey Edward Price
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Publication number: 20220097046Abstract: Instruments, systems, and methods for measuring optical density of microbiological samples are provided. In particular, optical density instruments providing improved safety, efficiency, comfort, and convenience are provided. Such optical density instruments include a handheld portion and a base station. The optical density instruments may be used in systems and methods for measuring optical density of biological samples.Type: ApplicationFiled: September 9, 2021Publication date: March 31, 2022Inventors: Perry D. STAMM, Joel Patrick HARRISON, Gregory R. MAES, Jeffrey Edward PRICE, Jack R. HOFFMANN, JR., John Kenneth KORTE, Daniel Joseph PINGEL, Walter J. CLYNES, Sean Gregory FURMAN, Leonard H. SCHLEICHER, Christopher George KOCHER, Brian David PETERSON, Jacky S. YAM
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Publication number: 20220097047Abstract: A method, computer program product, and apparatus are provided for controlling components of a detection device. The device may detect turbidity of liquid with sensors such as a density sensor and/or nephelometric sensor. A light modulation pattern may reduce or eliminate interference in sensor readings. Readings may be performed during off cycles of an illumination light to reduce interference but to provide improved visibility of a tube. Dark and light sensor readings may be performed with an emitter respectively off or on to account for ambient light in subsequent readings. Readings from the density sensor and/or nephelometric sensor may be used to calculate McFarland values. The device may be zeroed based on an emitter level that results in a sensor reading satisfying a predetermined criterion.Type: ApplicationFiled: September 14, 2021Publication date: March 31, 2022Inventors: Joel Patrick HARRISON, John Kenneth KORTE, Jeffrey Edward PRICE
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Patent number: 11195280Abstract: Methods include processing image data through a plurality of network stages of a progressively holistically nested convolutional neural network, wherein the processing the image data includes producing a side output from a network stage m, of the network stages, where m>1, based on a progressive combination of an activation output from the network stage m and an activation output from a preceding stage m?1. Image segmentations are produced. Systems include a 3D imaging system operable to obtain 3D imaging data for a patient including a target anatomical body, and a computing system comprising a processor, memory, and software, the computing system operable to process the 3D imaging data through a plurality of progressively holistically nested convolutional neural network stages of a convolutional neural network.Type: GrantFiled: June 8, 2018Date of Patent: December 7, 2021Assignee: The United States of America, As Represented by the Secretary, Department of Health and Human ServicesInventors: Adam Patrick Harrison, Ziyue Xu, Le Lu, Ronald M. Summers, Daniel Joseph Mollura
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Patent number: 11148144Abstract: A method, computer program product, and apparatus are provided for controlling components of a detection device. The device may detect turbidity of liquid with sensors such as a density sensor and/or nephelometric sensor. A light modulation pattern may reduce or eliminate interference in sensor readings. Readings may be performed during off cycles of an illumination light to reduce interference but to provide improved visibility of a tube. Dark and light sensor readings may be performed with an emitter respectively off or on to account for ambient light in subsequent readings. Readings from the density sensor and/or nephelometric sensor may be used to calculate McFarland values. The device may be zeroed based on an emitter level that results in a sensor reading satisfying a predetermined criterion.Type: GrantFiled: April 20, 2018Date of Patent: October 19, 2021Assignee: bioMerieux, Inc.Inventors: Joel Patrick Harrison, John Kenneth Korte, Jeffrey Edward Price
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Patent number: 11141733Abstract: Instruments, systems, and methods for measuring optical density of microbiological samples are provided. In particular, optical density instruments providing improved safety, efficiency, comfort, and convenience are provided. Such optical density instruments include a handheld portion and a base station. The optical density instruments may be used in systems and methods for measuring optical density of biological samples.Type: GrantFiled: October 17, 2019Date of Patent: October 12, 2021Assignee: BIOMERIEUX, INC.Inventors: Perry D. Stamm, Joel Patrick Harrison, Gregory R. Maes, Jeffrey Edward Price, Jack R. Hoffmann, Jr., John Kenneth Korte, Daniel Joseph Pingel, Walter J. Clynes, Sean Gregory Furman, Leonard H. Schleicher, Christopher George Kocher, Brian David Peterson, Jacky S. Yam
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Publication number: 20210204702Abstract: A resistive motion support mechanism joined to a mounting surface and to a base shaft for providing resistive support to the mounting surface as the mounting surface undergoes one or both of rotational and tilt movement relative to the base, the motion support mechanism including a support bearing connected to the mounting surface and to the base shaft which permits one or both of tilting and rotational motion of the mounting surface relative to the base; a pivot ball functionally attached to a portion of the base shaft; a resilient ring within a housing circumscribing the base shaft such that the resilient member is compressed between the housing and the base shaft by the relative movement between the base shaft and the mounting surface to provide a resistive force on the base shaft to resist the one or both of rotational and tilt movement; and, various means for varying the resistive force.Type: ApplicationFiled: July 12, 2019Publication date: July 8, 2021Inventor: Patrick HARRISON
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Patent number: 11040219Abstract: The present disclosure provides a clinical target volume delineation method and an electronic device. The method includes: receiving a radiotherapy computed tomography (RTCT) image; and obtaining a plurality of binary images by delineating a gross tumor volume (GTV), lymph nodes (LNs), and organs at risk (OARs) in the RTCT image. A SDMs for each of the binary images is calculated. The RTCT image and all the SDM are finally input into a clinical target volume (CTV) delineation model; and a CTV in the RTCT image is delineated by the CTV delineation model. An automatic delineation of the CTV of esophageal cancer are realized, a delineation efficiency is high and a delineation effect is good.Type: GrantFiled: August 21, 2019Date of Patent: June 22, 2021Assignee: Ping An Technology (Shenzhen) Co., Ltd.Inventors: Dakai Jin, Dazhou Guo, Le Lu, Adam Patrick Harrison
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Patent number: 10997720Abstract: A medical image classification method such as CT (or CAT) scans includes receiving the CT scan or medical image, inputting the medical image into an image classification model, which provides a cross entropy (CE) loss function and an aggregated cross entropy (ACE) loss function. According to the ACE loss function, image samples with generic label are used as input data during model training. The medical image can be classified by using the image classification model, and a classification of the medical image is thereby obtained. The present disclosure can classify indeterminate or general medical images and even unlabeled images and thus realize supervision of medical data. A device for applying the method is also provided.Type: GrantFiled: August 21, 2019Date of Patent: May 4, 2021Assignee: Ping An Technology (Shenzhen) Co., Ltd.Inventors: Bo Zhou, Adam Patrick Harrison, Jiawen Yao, Le Lu
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Patent number: 10937143Abstract: A fracture detection method executed by an electronic device is provided. The fracture detection method includes obtaining a to-be-detected image; using a Fully Convolutional Networks (FCN) model to process the to-be-detected image to obtain a fracture probability map of the to-be-detected image; performing a maximum pooling process on the fracture probability map to obtain a first fracture probability; extracting Regions of Interests (ROIs) of the to-be-detected image based on the FCN model; inputting the ROIs into a classification model to obtain a second fracture probability; calculating a product of the first fracture probability and the second fracture probability as a probability of a fracture phenomenon in the to-be-detected image. The present disclosure combines the FCN model and the ROIs to realize an automatic fracture detection, and the accuracy is higher. A device employing the method is also disclosed.Type: GrantFiled: August 21, 2019Date of Patent: March 2, 2021Assignee: Ping An Technology (Shenzhen) Co., Ltd.Inventors: Yirui Wang, Le Lu, Dakai Jin, Adam Patrick Harrison, Shun Miao
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Publication number: 20210056706Abstract: In a GTV segmentation method, a PET-CT image pair and an RTCT image of a human body are obtained. A PET image in the PET-CT image pair is aligned to the RTCT image to obtain an aligned PET image. A first PSNN performs a first GTV segmentation on the RTCT image to obtain a first segmentation image. The RTCT image and the aligned PET image are concatenated into a first concatenated image. A second PSNN performs a second GTV segmentation on the first concatenated image to obtain a second segmentation image. The RTCT image, the first segmentation image, and the second segmentation image are concatenated into a second concatenated image. A third PSNN performs a third GTV segmentation on the second concatenated image to obtain an object segmentation image.Type: ApplicationFiled: August 21, 2019Publication date: February 25, 2021Inventors: Dakai Jin, Dazhou Guo, Le Lu, Adam Patrick Harrison
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Publication number: 20210056672Abstract: A fracture detection method executed by an electronic device is provided. The fracture detection method includes obtaining a to-be-detected image; using a Fully Convolutional Networks (FCN) model to process the to-be-detected image to obtain a fracture probability map of the to-be-detected image; performing a maximum pooling process on the fracture probability map to obtain a first fracture probability; extracting Regions of Interests (ROIs) of the to-be-detected image based on the FCN model; inputting the ROIs into a classification model to obtain a second fracture probability; calculating a product of the first fracture probability and the second fracture probability as a probability of a fracture phenomenon in the to-be-detected image. The present disclosure combines the FCN model and the ROIs to realize an automatic fracture detection, and the accuracy is higher. A device employing the method is also disclosed.Type: ApplicationFiled: August 21, 2019Publication date: February 25, 2021Inventors: Yirui Wang, Le Lu, Dakai Jin, Adam Patrick Harrison, Shun Miao
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Publication number: 20210056684Abstract: A medical image classification method such as CT (or CAT) scans includes receiving the CT scan or medical image, inputting the medical image into an image classification model, which provides a cross entropy (CE) loss function and an aggregated cross entropy (ACE) loss function. According to the ACE loss function, image samples with generic label are used as input data during model training. The medical image can be classified by using the image classification model, and a classification of the medical image is thereby obtained. The present disclosure can classify indeterminate or general medical images and even unlabeled images and thus realize supervision of medical data. A device for applying the method is also provided.Type: ApplicationFiled: August 21, 2019Publication date: February 25, 2021Inventors: Bo Zhou, Adam Patrick Harrison, Jiawen Yao, Le Lu
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Publication number: 20210052918Abstract: The present disclosure provides a clinical target volume delineation method and an electronic device. The method includes: receiving a radiotherapy computed tomography (RTCT) image; and obtaining a plurality of binary images by delineating a gross tumor volume (GTV), lymph nodes (LNs), and organs at risk (OARs) in the RTCT image. A SDMs for each of the binary images is calculated. The RTCT image and all the SDM are finally input into a clinical target volume (CTV) delineation model; and a CTV in the RTCT image is delineated by the CTV delineation model. An automatic delineation of the CTV of esophageal cancer are realized, a delineation efficiency is high and a delineation effect is good.Type: ApplicationFiled: August 21, 2019Publication date: February 25, 2021Inventors: Dakai Jin, Dazhou Guo, Le Lu, Adam Patrick Harrison
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Patent number: 10929981Abstract: In a GTV segmentation method, a PET-CT image pair and an RTCT image of a human body are obtained. A PET image in the PET-CT image pair is aligned to the RTCT image to obtain an aligned PET image. A first PSNN performs a first GTV segmentation on the RTCT image to obtain a first segmentation image. The RTCT image and the aligned PET image are concatenated into a first concatenated image. A second PSNN performs a second GTV segmentation on the first concatenated image to obtain a second segmentation image. The RTCT image, the first segmentation image, and the second segmentation image are concatenated into a second concatenated image. A third PSNN performs a third GTV segmentation on the second concatenated image to obtain an object segmentation image.Type: GrantFiled: August 21, 2019Date of Patent: February 23, 2021Assignee: Ping An Technology (Shenzhen) Co., Ltd.Inventors: Dakai Jin, Dazhou Guo, Le Lu, Adam Patrick Harrison
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Publication number: 20200184647Abstract: Methods include processing image data through a plurality of network stages of a progressively holistically nested convolutional neural network, wherein the processing the image data includes producing a side output from a network stage m, of the network stages, where m>1, based on a progressive combination of an activation output from the network stage m and an activation output from a preceding stage m?1. Image segmentations are produced. Systems include a 3D imaging system operable to obtain 3D imaging data for a patient including a target anatomical body, and a computing system comprising a processor, memory, and software, the computing system operable to process the 3D imaging data through a plurality of progressively holistically nested convolutional neural network stages of a convolutional neural network.Type: ApplicationFiled: June 8, 2018Publication date: June 11, 2020Applicant: The United States of America, as represented by the Secretary Department of Health and Human ServiceInventors: Adam Patrick Harrison, Ziyue Xu, Le Lu, Ronald M. Summers, Daniel Joseph Mollura
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Publication number: 20200156063Abstract: Instruments, systems, and methods for measuring optical density of microbiological samples are provided. In particular, optical density instruments providing improved safety, efficiency, comfort, and convenience are provided. Such optical density instruments include a handheld portion and a base station. The optical density instruments may be used in systems and methods for measuring optical density of biological samples.Type: ApplicationFiled: October 17, 2019Publication date: May 21, 2020Inventors: Perry D. STAMM, Joel Patrick HARRISON, Gregory R. MAES, Jeffrey Edward PRICE, Jack R. HOFFMANN, JR., John Kenneth KORTE, Daniel Joseph PINGEL, Walter J. CLYNES, Sean Gregory FURMAN, Leonard H. SCHLEICHER, Christopher George KOCHER, Brian David PETERSON, Jacky S. YAM
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Patent number: 10603659Abstract: Methods, systems, and computer program products for detecting formation of a droplet at a distal end of a pipette tip attached to a pipette. The methods, systems, and computer program products provide dispensing a fluid from the pipette tip, measuring pipette pressure in real time at an internal portion of the pipette while the fluid is dispensed, determining a plurality of pressure differences, estimating a plurality of rate of change in pipette pressure values during a given time interval, detecting formation of the droplet responsive to determining certain conditions are met, and stopping the dispensing of the fluid from the pipette tip or moving the pipette when the droplet is detected.Type: GrantFiled: September 28, 2017Date of Patent: March 31, 2020Assignee: bioMerieux, Inc.Inventors: Daniel Oliver Luebbert, Daniel Joseph Pingel, Joel Patrick Harrison, Jeremey Joseph Pionke