Abstract: Provided herein are methods, compositions, and kits for preparing biological samples for multiplex spatial gene expression and proteomic analysis, such as determining a location of a nucleic acid analyte and a protein analyte in a biological sample.

Abstract: Described herein is a mobile device with an optical detector including: at least one illumination source adapted to generate at least one illumination pattern for illuminating an object, where the illumination pattern includes a regular and/or constant and/or periodic pattern; at least one sensor element having a matrix of optical sensors, the optical sensors each having a light-sensitive area, where each optical sensor is configured to generate at least one sensor signal in response to an illumination of the light-sensitive area by at least one light beam propagating from the object to the detector; and at least one evaluation device adapted to determine at least one region of interest.

Abstract: The Invention is an apparatus for refilling ink cartridges, such as ink cartridges for ink jet printers. The cartridge is attached to a table. The table is rotatable with respect to a base through a series of stations. The stations include guides to locate an aperture in the ink cartridge and to locate a reservoir for filling the ink cartridge. A cartridge sealing assembly seals the aperture, but allows a hollow pin to be inserted for filling the cartridge.