Abstract: A improved mechanism to create rotational mechanical advantage from an acceleration field while eliminating reactant gyroscopic force, consisting of a tower mount assembly (10) rotationally connected to a gimbal assembly (20). A conic counterweight arm assembly (30) rigidly attached to the crown plate (28) of the gimbal assembly (20). A powered action arm assembly (37) rotationally connected in a horizontal plane to the crown plate shaft (29) of the gimbal assembly (20) and rotationally contacts the conic counterweight arm assembly (30) via a wheel and track. A gravity arm assembly (55) rotationally connected in a horizontal plane, adjacent to the first arm assembly, to the gimbal assembly (20) and rotationally contacts the conic counterweight arm assembly (30) via a wheel and track.

Abstract: A mechanism to create rotational mechanical advantage from an acceleration field consisting of a gravity arm assembly (14) rotationally connected in a horizontal plane to a gimbal assembly (41). A powered action arm assembly (21) rotationally connected in a horizontal plane, adjacent to the first arm assembly, to the gimbal assembly (41). A counterweight arm assembly (72), connecting at one end to a gearbox assembly (64) and connecting at the opposite end to an attachment mounting assembly (87), all vertically connected to the gimbal assembly (41). A mounting stand assembly (80) to rotationally connect to the gimbal assembly (41). An electrical control assembly (100) to controllably power the action arm assembly. The gravity arm and action arm assemblies are balanced about the gimbal assembly by the counterweight arm assemblies.

Abstract: A mechanism to create rotational mechanical advantage from an acceleration field consisting of a gravity arm assembly (14) rotationally connected in a horizontal plane to a gimbal assembly (41). A powered action arm assembly (21) rotationally connected in a horizontal plane, adjacent to the first arm assembly, to the gimbal assembly (41). A counterweight arm assembly (72), connecting at one end to a gearbox assembly (64) and connecting at the opposite end to an attachment mounting assembly (87), all vertically connected to the gimbal assembly (41). A mounting stand assembly (80) to rotationally connect to the gimbal assembly (41). An electrical control assembly (100) to controllably power the action arm assembly. The gravity arm and action arm assemblies are balanced about the gimbal assembly by the counterweight arm assemblies.

Abstract: In one embodiment, a method includes retrieving a playlist for a video stream of video content for a client. The playlist is for portions of video content for the video stream. A traffic shaping service determines a set of rules for the playlist for a set of portions in the plurality of portions where each rule is associated with a network condition. For each rule, the method performs: dynamically allocating a port and setting a network condition to apply to the port according to the rule. During playback of the video content, the traffic shaping service receives a request for a portion from the client and determines a port associated with the request for the portion. The method then sends a traffic shaped portion through the determined port where the network condition is applied to the traffic shaped portion based on the network condition being set on the port.

Abstract: In one embodiment, a method includes retrieving a playlist for a video stream of video content for a client. The playlist is for portions of video content for the video stream. A traffic shaping service determines a set of rules for the playlist for a set of portions in the plurality of portions where each rule is associated with a network condition. For each rule, the method performs: dynamically allocating a port and setting a network condition to apply to the port according to the rule. During playback of the video content, the traffic shaping service receives a request for a portion from the client and determines a port associated with the request for the portion. The method then sends a traffic shaped portion through the determined port where the network condition is applied to the traffic shaped portion based on the network condition being set on the port.

Abstract: In one embodiment, a method receives a request for a video stream of video content from a client. A playlist for the video stream is retrieved. The playlist is for a plurality of portions of video content. A traffic shaping service adjusts the playlist for a set of portions in the plurality of portions according to a set of rules where adjusting allows the service to perform traffic shaping for the set of portions. The method then sends the adjusted playlist to the client. During playback of the video content at the client, the traffic shaping service receives a request for a portion in the set of portions from the client using the adjusted playlist. The method determines a rule to apply to the portion where the rule is associated with a network condition and simulates the network condition for the portion to perform the traffic shaping service.

Abstract: The present invention relates to agents capable of treating or preventing an allergic disorder in an animal and a method of screening for these agents. In particular, the present invention relates to an isolated nucleic acid molecule comprising (a) an isolated nucleic acid molecule whose expression is modulated in a mammal suffering from or at elevated risk of developing an allergic condition, such that the level of expression of the nucleic acid differs from that in a mammal which is not suffering from or at elevated risk of developing the allergic condition, in which the nucleic acid comprises a sequence selected from the group consisting of sequences identified by probes 243610 at on human chromosome 9q21.13 at locus 138255, 1556097 at on human chromosome 15q25.2 and 242743 at on human chromosome 16p12.

Abstract: The present invention relates to genes whose level of expression is different in allergic animals compared with non-allergic animals. In particular, the present invention relates to a method for predicting the development of an allergic disorder in a mammal by determining the gene expression pattern of a panel of specific sequences comprising CAMK2D and CDH1 within a nucleic acid pool that have been predetermined to either increase or decrease in response to allergy.

Abstract: The present invention relates to methods for diagnosing an allergic disorder, predicting the development of an allergic disorder in an animal, monitoring the progress of therapy targeted at an allergic disorder, classification of the allergic disorder into one or more clinical/immunological phenotypes, and/or determining the potentional responsiveness of individual animals suffering from or at risk of an allergic disorder to particular forms of therapy. In particular, the present invention relates to a method of diagnosing and/or predicting the development of an allergic disorder in an animal, comprising the step of analysing a biological sample from the animal to determine the level of activation of one or more allergy-associated genes, in which the level of activation is diagnostic of the allergic disorder or predicative of the relative risk for the development of an allergic disorder in the animal.

Abstract: The present invention relates to the use of immunomodifying agents to effect change in the T helper-type 1 (TH1) or T helper-type 2 (TH2) arms of the immune response and thereby treat TH1 or TH2 mediated diseases. In particular, the present invention relates to a method of altering a specific immune response in an individual comprising: i). administering to an individual in need thereof an effective amount of an antigen in immunotherapeutic form, wherein said immune response is down regulated; and ii). subsequently administering to the individual an effective amount of an immunomodifying agent comprising said antigen in immunogenic form.

Abstract: The present invention relates to a method for improving the effectiveness of immunotherapy. In particular, the present invention relates to method for predicting the development of an allergic disease in a subject, comprising providing a biological sample; stimulating said sample with an allergen in vitro to produce one or more cytokine(s); determining which cytokines are present; and correlating development of an allergic disease with the presence or absence of particular cytokines.

Abstract: A method for diagnosis of immunologically-mediated conditions such as allergic conditions, autoimmune diseases and immunological deficiency, and of assessing immunological reactivity associated with conditions such as viral infections, cancer, AIDS, tissue transplantation and the like. the method comprises: Taking a sample from a subject suspected to be manifesting an abnormal immunological reaction; isolating leukocytes from subject and a control; measuring the level of expression of a transcription factor in unstimulated leukocytes; stimulating the leukocytes by exposure to a stimulus; measuring the level of expression of a transcription factor in stimulated leukocytes; comparing results of stimulated and unstimulated leukocytes from subject and control; a significant difference in expression between the subject and control is indicative of an abnormal immunological reaction.