Patents by Inventor Patrick HONG

Patrick HONG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods to genetically modify cells for delivery of therapeutic proteins
    Patent number: 12534744
    Abstract: The present disclosure provides methods to genetically modify cells by insertion of an artificial exon (ArtEx) for delivery of therapeutic proteins in specific cell types and more particularly engineered cells for expression of a transgene into the brain of a patient.
    Type: Grant
    Filed: May 6, 2021
    Date of Patent: January 27, 2026
    Assignee: CELLECTIS S.A.
    Inventors: Alexandre Juillerat, Philippe Duchateau, Patrick Hong, Laurent Poirot, Brian Busser, Alex Boyne
  • METHODS TO GENETICALLY MODIFY CELLS FOR DELIVERY OF THERAPEUTIC PROTEINS
    Publication number: 20230279440
    Abstract: The present disclosure provides methods to genetically modify cells by insertion of an artificial exon (ArtEx) for delivery of therapeutic proteins in specific cell types and more particularly engineered cells for expression of a transgene into the brain of a patient.
    Type: Application
    Filed: May 6, 2021
    Publication date: September 7, 2023
    Inventors: Alexandre JUILLERAT, Philippe DUCHATEAU, Patrick HONG, Laurent POIROT, Brian BUSSER, Alex BOYNE
  • METHODS FOR TARGETED INSERTION OF EXOGENOUS SEQUENCES IN CELLULAR GENOMES
    Publication number: 20230212613
    Abstract: The present disclosure provides methods for targeted insertion of an exogenous sequence at a genomic locus in a cell, wherein said insertion is induced by a sequence-specific endonuclease that has cleavage activity at said locus, at least 5 hours before the introduction into said cell of a DNA template comprising said exogenous sequence.
    Type: Application
    Filed: May 6, 2021
    Publication date: July 6, 2023
    Inventors: Ming YANG, Alexandre JUILLERAT, Philippe DUCHATEAU, Patrick HONG