Abstract: An injection device for dispensing a product, the injection device including a moveable element which is moved for a dispensing operation, a spring, a product container holder and a product container, wherein the spring pushes against the moveable element to move the moveable element to an initial position after the dispensing operation has ended and against the product container to seat the product container in the product container holder.

Abstract: An injection device for delivery of a fluid medicament includes a housing defining a longitudinal axis and enclosing an injection mechanism. An end cap is fixed to the housing and limits the injection mechanism in a proximal direction. A closure cap is releasably connected to the end cap by a releasable snap fit connection thereby closing the injection device. The releasable snap fit connection is established before medicament delivery by relative axial movement along the longitudinal axis between the closure cap and the housing whereby a wall of the closure cap is elastically deformed, and the releasable snap fit connection is configured to be released after medicament delivery by relative rotational movement around the longitudinal axis between the closure cap and the housing whereby the wall of the closure cap is elastically deformed.

Abstract: A safety mechanism for a drug delivery device for dispensing a liquid drug from a reservoir through a needle includes a housing defining a longitudinal axis, a needle cover movable along the longitudinal axis between a needle covering position and a retracted position, a movable lock element with a locking position to prevent the needle cover from being moved out of the needle covering position, and a trigger member movable along the longitudinal axis relative to the housing. The trigger member is operatively coupled to the lock element and a movement of the trigger member along the longitudinal axis causes the lock element to move out of the locking position allowing the needle cover to be moved out of the needle covering position.

Abstract: A disposable syringe unit for an injection device adapted for releasable attachment to a reusable drive unit of the injection device includes a prefilled syringe with a reservoir and an injection needle, a syringe holder for holding the prefilled syringe, a cover member guided by guiding means thereby movable along the longitudinal axis relative to the syringe holder between a covering position in which the injection needle is covered and a retracted position in which the injection needle protrudes from the cover member, and a cap releasably attached to a distal end of the cover member or the syringe holder. Apart from the prefilled syringe, the syringe unit includes in total not more than three separate parts.

Abstract: A smart injection system includes at least one mobile device and at least one injection device with electronics that can be used by a user. The mobile device is configured to wirelessly receive information regarding a glycemic state of the user, use this information to automatically calculate medication doses to be administered, and to transmit the calculated doses to the injection device.

Abstract: Systems and methods for lineage data tracking are disclosed. Domain-specific code is obtained in response to a build request and the domain-specific code is converted to process code. The domain-specific code includes an instance of a domain-specific language configured for a specific domain. The process code includes at least one breadcrumb instrumentation element automatically inserted during the conversion process by a conversion engine and the breadcrumb instrumentation element is not defined in the domain-specific code. The process code is executed including execution of one or more activities defined by the domain-specific code and the at least one breadcrumb instrumentation element. During execution of the at least one breadcrumb instrumentation element, a lineage data structure is generated. The lineage data structure is configured to store data elements representative of a mapping between an input data element and an output data element. The lineage data structure is stored in a data store.

Abstract: An infusion apparatus for delivering medication includes a housing, a drive device, a product container, and a battery compartment with a battery compartment lid having a plastic part and a metal cap. The plastic part is electrically non-conductive and the metal cap includes a proximal surface facing the plastic part and a distal surface facing an interior of the battery compartment. The metal cap includes through-holes and the plastic part includes protrusions extending through the through-holes to form an arrangement in which a first terminal of a battery positioned in the battery compartment can contact the distal surface of the metal cap, resulting in electrical contact between the metal cap and the first terminal, and in which a second terminal of the battery positioned in the battery compartment contacts the arrangement to prevent electrical contact to prevent reverse poling of the battery by reverse battery insertion into the battery compartment.

Abstract: A fill port for filling a liquid medicament into a reservoir located inside a drug delivery device includes insert fixed in a passage of a wall of the drug delivery device, and a pierceable fill port sealing is sandwiched between the insert and both the housing of the drug delivery device and the reservoir to provide a fluid-tight sealing between the reservoir and the housing.

Abstract: An actuation device for an administration device and/or an administration device for the parenteral administration of a medicament, includes a rotary element rotatable through an angle proportional to a dose volume, a pushing element configured to act on a drive, a magnetic element operatively connected to the rotary element and/or the pushing element and movable therewith relative the instrument housing, a sensor arrangement with at least three magnetic field sensors, each with a directivity with regard to the direction of a magnetic field component, and an evaluation device. At least a first and a second of the magnetic field sensors are fitted such that they selectively sense the changes in the field component in the circumferential direction and the at least third magnetic field sensor is fitted such that it selectively senses the changes in the field component in the axial direction.

Abstract: An administration device and a method for a guided operation of an administration device for a medication includes: a pre-selection means by means of which a pre-selected quantity can be mechanically or electronically set and/or stored, and a controller containing a timer configured such that, when an operating means is actuated, the timer continuously measures a duration between when the output means is no longer moved by the drive to when the operating means is transferred to the non-actuated state. The controller identifies the discharge quantity as a priming quantity if the duration is shorter than a defined threshold duration.

Abstract: An infusion apparatus for delivering medication includes a housing, a drive mechanism, a force sensor, and a transfer element. The drive mechanism comprises first and second conveying elements, the second conveying element for advancing a plug in a reservoir in the distal direction, the first conveying element with limited axial movement relative to the housing but rotatable to cause an ejecting or resetting movement of the second conveying element. The force sensor is arranged along a central axis between the housing and the proximal end of the drive mechanism. The transfer element is axially arranged between the force sensor and the first conveying element and the force sensor bears axial forces exerted by the ejection movement. The second conveying element moves the transfer element away from the first conveying element against the bias of a restoring force such that the force sensor bears axial forces exerted by the resetting movement.

Abstract: A modular, semi-disposable patch pump for conducting a medical therapy includes a pump unit releasably connected to a reservoir unit by means of a bayonet connection; and a housing design for supporting both reliability and ease of use of said connection.

Abstract: An insertion mechanism for a cannula includes a cannula housing, a displaceable cannula, at least one cannula holder, an insertion spring, a triggering element, and a safety device. The safety device, in a secured state, holds the triggering element in a blocked position against a force of the insertion spring and, in a released state, releases the triggering element such that the triggering element is movable into a release position by the force of said insertion energy store and the at least one cannula holder is able to move relative to the cannula housing, driven by the insertion energy store, so as to trigger or implement an insertion movement or insertion. To reach the released state, the safety mechanism is heatable by a heating element and softened and/or weakened with respect to its mechanical carrying or holding capacity, or severed or at least partially or completely melted.

Abstract: An autoinjector for dispensing a liquid product, particularly a drug, comprising: an electronic module with a sensor configured to measure the axial movement of a signal element (11) from a position at the start of the dispensing, wherein the signal element (11) is slaved in the dispensing direction, to a position at the end of the dispensing, wherein the signal element (11) strikes the signal stop (12a).

Abstract: A drive for a drug delivery device includes a drive mechanism with a drive shaft, a pinion arranged on the drive shaft and a cycloidal drive. The cycloidal drive has a cycloidal disc and a ring gear. The cycloidal disc is driven in an eccentric motion by means of a planet gear, which meshes with the pinion on the drive shaft and with an internal gear of the cycloidal disc. Further, the present application also relates to a drug delivery device with the aforementioned drive.

Abstract: An insertion mechanism for a cannula includes a cannula housing, a displaceable cannula, at least one cannula holder, an insertion spring, a triggering element, and a safety device. The safety device, in a secured state, holds the triggering element in a blocked position against a force of the insertion spring and, in a released state, releases the triggering element such that the triggering element is movable into a release position by the force of said insertion energy store and the at least one cannula holder is able to move relative to the cannula housing, driven by the insertion energy store, so as to trigger or implement an insertion movement or insertion. To reach the released state, the safety mechanism is heatable by a heating element and softened and/or weakened with respect to its mechanical carrying or holding capacity, or severed or at least partially or completely melted.

Abstract: An autoinjector for dispensing a liquid product, in particular a highly viscous medication, includes: a housing, a product container, which is arranged in the housing and has a slidable piston, wherein the piston can be slid in a dispensing direction in order to dispense the product contained in the product container, a forward drive element, which acts on the piston as the product is being dispensed, a first spring, which is preloaded such that the product can be dispensed from the product container by the sliding of the forward drive element and the piston, and a rotation element, which is operatively coupled to the forward drive element, wherein the first spring acts on the rotation element in such a way that the rotation element is set into rotation in order to dispense the product, wherein the rotation element or the forward drive element has a thread having a variable pitch.

Abstract: An injection device for dispensing a product, the injection device including a moveable element which is moved for a dispensing operation, a spring, a product container holder and a product container, wherein the spring pushes against the moveable element to move the moveable element to an initial position after the dispensing operation has ended and against the product container to seat the product container in the product container holder.

Abstract: A disposable, single-dose delivery device for self-administration by a patient of a predefined amount or dose of drug from a reservoir through an outlet of the reservoir includes a device operation lock to prevent a delivery operation of the delivery device as shipped to the patient, an embedded electronic control unit with a wireless receiver for receiving an unlock command or message, and an electromechanical actuator for mechanically unlocking the device operation lock and enabling delivery device operation by the patient. The control unit is configured to activate the actuator instantaneously and unconditionally upon receipt of the unlock command. The unlocking mechanism of the delivery device is adapted to be activated from remote in response to a confirmative message indicative of additional double check by a Health Care Professional HCP or expert system.

Abstract: A delivery device for administering a drug includes a housing, a reservoir and a drive device with a movable piston rod. The piston rod is guided through an aperture in an inner or outer wall of the housing. The aperture is sealed but allows the piston rod to move. The shape of the circumference of the cross-section of the piston rod is approximately a non-trivial curve of constant width.