Patents by Inventor Patrick J. Crutcher

Patrick J. Crutcher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid prodrugs
    Patent number: 11479576
    Abstract: The invention relates to a method of treating a mitochondrial DNA depletion syndrome, comprising administering to a patient a therapeutically-effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: June 19, 2020
    Date of Patent: October 25, 2022
    Assignee: AVALO THERAPEUTICS, INC.
    Inventors: Stephen B. Thomas, Patrick J. Crutcher
  • NUCLEOTIDE PRODRUGS
    Publication number: 20210139525
    Abstract: The invention relates to nucleotide prodrugs and pharmaceutical preparations thereof. The invention further relates using the prodrugs of the invention in the treatment of mitochondrial DNA (mtDNA) depletion syndrome (MDS).
    Type: Application
    Filed: January 7, 2019
    Publication date: May 13, 2021
    Inventors: Stephen B. Thomas, Patrick J. Crutcher, Fabrizio Pertusati, Elisa Pileggi
  • NUCLEIC ACID PRODRUGS
    Publication number: 20210101923
    Abstract: The invention relates to nucleotide prodrugs and pharmaceutical preparations thereof. The invention further relates to methods of treatment using the novel prodrugs of the invention.
    Type: Application
    Filed: June 19, 2020
    Publication date: April 8, 2021
    Inventors: Stephen B. Thomas, Patrick J. Crutcher
  • Nucleic acid prodrugs
    Patent number: 10745435
    Abstract: The invention relates to deoxynucleotide prodrugs and pharmaceutical preparations thereof. The deoxynucleotide prodrugs include, but are not limited to, The invention further relates to methods of treatment of a mitochondrial DNA (mtDNA) depletion syndrome (MDS) by administering a therapeutically-effective amount of a deoxynucleotide prodrug of the present invention.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: August 18, 2020
    Assignee: CERECOR, INC.
    Inventors: Stephen B. Thomas, Patrick J. Crutcher
  • NUCLEIC ACID PRODRUGS
    Publication number: 20180346508
    Abstract: The invention relates to nucleotide prodrugs and pharmaceutical preparations thereof. The invention further relates to methods of treatment using the novel prodrugs of the invention.
    Type: Application
    Filed: November 16, 2016
    Publication date: December 6, 2018
    Inventors: Stephen B. Thomas, Patrick J. Crutcher