Patents by Inventor Patrick J. Gaines

Patrick J. Gaines has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Flea head, nerve cord, hindgut and malpighian tubule nucleic acid molecules, proteins and uses thereof
    Patent number: 8088903
    Abstract: The present invention relates to flea head, nerve cord, hindgut and Malpighian tubule proteins; to flea head, nerve cord, hindgut and Malpighian tubule nucleic acid molecules, including those that encode such flea head, nerve cord, hindgut and Malpighian tubule proteins; to antibodies raised against such flea head, nerve cord, hindgut and Malpighian tubule proteins; and to compounds that inhibit flea head, nerve cord, hindgut and Malpighian tubule protein activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising proteins, nucleic acid molecules, antibodies, or protective compounds derived from proteins of the present invention as well as the use of such therapeutic compositions to protect animals from flea infestation.
    Type: Grant
    Filed: December 1, 2006
    Date of Patent: January 3, 2012
    Assignee: Heska Corporation
    Inventors: Kevin S. Brandt, Patrick J. Gaines, Dan T. Stinchcomb, Nancy Wisnewski
  • Flea peritrophin nucleic acid molecules
    Patent number: 7662622
    Abstract: The present invention relates to flea peritrophin proteins; to flea peritrophin nucleic acid molecules, including those that encode such flea peritrophin proteins; to antibodies raised against such proteins; and to compounds that inhibit the activity of such proteins. The present invention also includes methods to obtain and use such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. The present invention also includes therapeutic compositions comprising such inhibitory compounds, particularly those that specifically inhibit flea peritrophin activity, as well as the use of such therapeutic compositions to treat animals.
    Type: Grant
    Filed: July 16, 2007
    Date of Patent: February 16, 2010
    Assignee: Heska Corporation
    Inventors: Patrick J. Gaines, Nancy Wisnewski
  • FLEA HEAD, NERVE CORD, HINDGUT AND MALPIGHIAN TUBULE NUCLEIC ACID MOLECULES, PROTEINS AND USES THEREOF
    Publication number: 20090186008
    Abstract: The present invention relates to flea head, nerve cord, hindgut and Malpighian tubule proteins; to flea head, nerve cord, hindgut and Malpighian tubule nucleic acid molecules, including those that encode such flea head, nerve cord, hindgut and Malpighian tubule proteins; to antibodies raised against such flea head, nerve cord, hindgut and Malpighian tubule proteins; and to compounds that inhibit flea head, nerve cord, hindgut and Malpighian tubule protein activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising proteins, nucleic acid molecules, or protective compounds derived from proteins of the present invention as well as the use of such therapeutic compositions to protect animals from flea infestation.
    Type: Application
    Filed: February 20, 2008
    Publication date: July 23, 2009
    Inventors: KEVIN S. BRANDT, PATRICK J. GAINES, DAN T. STINCHCOMB, NANCY WISNEWSKI
  • FLEA ALLANTOINASE PROTEINS AND USES THEREOF
    Publication number: 20090042230
    Abstract: The present invention relates to flea allantoinase proteins; to flea allantoinase nucleic acid molecules, including those that encode such flea allantoinase proteins; to antibodies raised against such proteins; and to compounds that inhibit the activity of such proteins. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. The present invention also includes therapeutic compositions comprising such inhibitory compounds, particularly those that specifically inhibit flea allantoinase activity, as well as the use of such therapeutic compositions to treat animals.
    Type: Application
    Filed: March 19, 2008
    Publication date: February 12, 2009
    Inventors: PATRICK J. GAINES, NANCY WISNEWSKI
  • Flea head, nerve cord, hindgut and malpighian tubule proteins
    Patent number: 7348410
    Abstract: The present invention relates to flea head, nerve cord, hindgut and Malpighian tubule proteins; to flea head, nerve cord, hindgut and Malpighian tubule nucleic acid molecules, including those that encode such flea head, nerve cord, hindgut and Malpighian tubule proteins; to antibodies raised against such flea head, nerve cord, hindgut and Malpighian tubule proteins; and to compounds that inhibit flea head, nerve cord, hindgut and Malpighian tubule protein activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising proteins, nucleic acid molecules, or protective compounds derived from proteins of the present invention as well as the use of such therapeutic compositions to protect animals from flea infestation.
    Type: Grant
    Filed: October 29, 2004
    Date of Patent: March 25, 2008
    Assignee: Heska Corporation
    Inventors: Patrick J. Gaines, Nancy Wisnewski
  • Flea peritrophin nucleic acid molecules, proteins and uses thereof
    Patent number: 7247447
    Abstract: The present invention relates to flea peritrophin proteins; to flea peritrophin nucleic acid molecules, including those that encode such flea peritrophin proteins; to antibodies raised against such proteins; and to compounds that inhibit the activity of such proteins. The present invention also includes methods to obtain and use such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. The present invention also includes therapeutic compositions comprising such inhibitory compounds, particularly those that specifically inhibit flea peritrophin activity, as well as the use of such therapeutic compositions to treat animals.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: July 24, 2007
    Assignee: Heska Corporation
    Inventors: Patrick J. Gaines, Nancy Wisnewski
  • Flea allantoinase proteins and uses thereof
    Patent number: 6905682
    Abstract: The present invention relates to flea allantoinase proteins; to flea allantoinase nucleic acid molecules, including those that encode such flea allantoinase proteins; to antibodies raised against such proteins; and to compounds that inhibit the activity of such proteins. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. The present invention also includes therapeutic compositions comprising such inhibitory compounds, particularly those that specifically inhibit flea allantoinase activity, as well as the use of such therapeutic compositions to treat animals.
    Type: Grant
    Filed: June 25, 2002
    Date of Patent: June 14, 2005
    Assignee: Heska Corporation
    Inventors: Patrick J. Gaines, Nancy Wisnewski
  • Flea head, nerve cord, hindgut and malpighian tubule nucleic acid molecules, proteins and uses thereof
    Publication number: 20040067516
    Abstract: The present invention relates to flea head, nerve cord, hindgut and Malpighian tubule proteins; to flea head, nerve cord, hindgut and Malpighian tubule nucleic acid molecules, including those that encode such flea head, nerve cord, hindgut and Malpighian tubule proteins; to antibodies raised against such flea head, nerve cord, hindgut and Malpighian tubule proteins; and to compounds that inhibit flea head, nerve cord, hindgut and Malpighian tubule protein activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising proteins, nucleic acid molecules, antibodies, or protective compounds derived from proteins of the present invention as well as the use of such therapeutic compositions to protect animals from flea infestation.
    Type: Application
    Filed: July 16, 2003
    Publication date: April 8, 2004
    Inventors: Kevin S. Brandt, Patrick J. Gaines, Dan T. Stinchcomb, Nancy Wisnewski
  • Flea peritrophin nucleic acid molecules, proteins and uses thereof
    Publication number: 20030220487
    Abstract: The present invention relates to flea peritrophin proteins; to flea peritrophin nucleic acid molecules, including those that encode such flea peritrophin proteins; to antibodies raised against such proteins; and to compounds that inhibit the activity of such proteins. The present invention also includes methods to obtain and use such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. The present invention also includes therapeutic compositions comprising such inhibitory compounds, particularly those that specifically inhibit flea peritrophin activity, as well as the use of such therapeutic compositions to treat animals.
    Type: Application
    Filed: March 27, 2003
    Publication date: November 27, 2003
    Inventors: Patrick J. Gaines, Nancy Wisnewski
  • Flea peritrophin nucleic acid molecules, proteins and uses thereof
    Patent number: 6576750
    Abstract: The present invention relates to flea peritrophin proteins; to flea peritrophin nucleic acid molecules, including those that encode such flea peritrophin proteins; to antibodies raised against such proteins; and to compounds that inhibit the activity of such proteins. The present invention also includes methods to obtain and use such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. The present invention also includes therapeutic compositions comprising such inhibitory compounds, particularly those that specifically inhibit flea peritrophin activity, as well as the use of such therapeutic compositions to treat animals.
    Type: Grant
    Filed: October 11, 2000
    Date of Patent: June 10, 2003
    Assignee: Heska Corporation
    Inventors: Patrick J. Gaines, Nancy Wisnewski
  • Flea head, nerve cord, hindgut and malpighian tubule nucleic acid molecules, proteins and uses thereof
    Publication number: 20030073827
    Abstract: The present invention relates to flea head, nerve cord, hindgut and Malpighian tubule proteins; to flea head, nerve cord, hindgut and Malpighian tubule nucleic acid molecules, including those that encode such flea head, nerve cord, hindgut and Malpighian tubule proteins; to antibodies raised against such flea head, nerve cord, hindgut and Malpighian tubule proteins; and to compounds that inhibit flea head, nerve cord, hindgut and Malpighian tubule protein activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising proteins, nucleic acid molecules, or protective compounds derived from proteins of the present invention as well as the use of such therapeutic compositions to protect animals from flea infestation.
    Type: Application
    Filed: November 21, 2001
    Publication date: April 17, 2003
    Inventors: Kevin S. Brandt, Patrick J. Gaines, Dan T. Stinchcomb, Nancy Wisnewski
  • Flea allantoinase nucleic acid molecules, proteins and uses thereof
    Patent number: 6469152
    Abstract: The present invention relates to flea allantoinase proteins; to flea allantoinase nucleic acid molecules, including those that encode such flea allantoinase proteins; to antibodies raised against such proteins; and to compounds that inhibit the activity of such proteins. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. The present invention also includes therapeutic compositions comprising such inhibitory compounds, particularly those that specifically inhibit flea allantoinase activity, as well as the use of such therapeutic compositions to treat animals.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: October 22, 2002
    Assignee: Heska Corporation
    Inventors: Patrick J. Gaines, Nancy Wisnewski
  • Flea protease proteins, nucleic acid molecules and uses thereof
    Patent number: 6406900
    Abstract: The present invention relates to flea serine protease proteins and flea cysteine protease proteins; to flea serine protease and cysteine protease nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins; and to compounds that inhibit flea serine protease and/or cysteine protease activities. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitors. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies, and/or inhibitors as well as the use of such therapeutic compositions to protect a host animal from flea infestation.
    Type: Grant
    Filed: January 8, 1998
    Date of Patent: June 18, 2002
    Assignee: Heska Corporation
    Inventors: Shirley Wu Hunter, Gary L. Stiegler, Patrick J. Gaines
  • Flea allantoinase nucleic acid molecules, proteins and uses thereof
    Publication number: 20020026041
    Abstract: The present invention relates to flea allantoinase proteins; to flea allantoinase nucleic acid molecules, including those that encode such flea allantoinase proteins; to antibodies raised against such proteins; and to compounds that inhibit the activity of such proteins. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. The present invention also includes therapeutic compositions comprising such inhibitory compounds, particularly those that specifically inhibit flea allantoinase activity, as well as the use of such therapeutic compositions to treat animals.
    Type: Application
    Filed: June 28, 2001
    Publication date: February 28, 2002
    Inventors: Patrick J. Gaines, Nancy Wisnewski
  • Flea serine protease nucleic acid molecules and uses thereof
    Patent number: 6232096
    Abstract: The present invention relates to flea serine protease proteins, aminopeptidase proteins and flea cysteine protease proteins; to flea serine protease, aminopeptidase and cysteine protease nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins; and to compounds that inhibit flea serine protease, aminopeptidase and/or cysteine protease activities. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitors. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies, and/or inhibitors as well as the use of such therapeutic compositions to protect a host animal from flea infestation.
    Type: Grant
    Filed: August 5, 1997
    Date of Patent: May 15, 2001
    Assignee: Heska Corporation
    Inventors: Robert B. Grieve, Keith E. Rushlow, Shirley Wu Hunter, Glenn R. Frank, Gary L. Stiegler, Patrick J. Gaines, Gary Silver
  • Flea protease proteins, nucleic acid molecules, and uses thereof
    Patent number: 6210920
    Abstract: The present invention relates to flea serine protease proteins and flea cysteine protease proteins; to flea serine protease and cysteine protease nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins; and to compounds that inhibit flea serine protease and/or cysteine protease activities. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitors. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies, and/or inhibitors as well as the use of such therapeutic compositions to protect a host animal from flea infestation.
    Type: Grant
    Filed: November 15, 1996
    Date of Patent: April 3, 2001
    Assignee: Heska Corporation
    Inventors: Shirley Wu Hunter, Gary L. Stiegler, Patrick J. Gaines
  • Flea protease proteins, nucleic acid molecules, and uses thereof
    Patent number: 6204010
    Abstract: The present invention relates to flea serine protease proteins; to flea serine protease nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins; and to compounds that inhibit flea serine protease activities. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitors. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies, and/or inhibitors as well as the use of such therapeutic compositions to protect a host animal from flea infestation.
    Type: Grant
    Filed: February 27, 1998
    Date of Patent: March 20, 2001
    Assignee: Heska Corporation
    Inventors: Gary L. Stiegler, Patrick J. Gaines
  • Flea protease proteins and uses thereof
    Patent number: 6177258
    Abstract: The present invention relates to flea serine protease proteins and flea cysteine protease proteins; to flea serine protease and cysteine protease nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins; and to compounds that inhibit flea serine protease and/or cysteine protease activities. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitors. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies, and/or inhibitors as well as the use of such therapeutic compositions to protect a host animal from flea infestation.
    Type: Grant
    Filed: January 8, 1998
    Date of Patent: January 23, 2001
    Assignee: Heska Corporation
    Inventors: Shirley Wu Hunter, Gary L. Stiegler, Patrick J. Gaines
  • Flea protease proteins, nucleic acid molecules, and uses thereof
    Patent number: 6156556
    Abstract: The present invention relates to flea serine protease proteins and flea cysteine protease proteins; to flea serine protease and cysteine protease nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins; and to compounds that inhibit flea serine protease and/or cysteine protease activities. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitors. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies, and/or inhibitors as well as the use of such therapeutic compositions to protect a host animal from flea infestation.
    Type: Grant
    Filed: January 8, 1998
    Date of Patent: December 5, 2000
    Assignee: Heska Corporation
    Inventors: Shirley Wu Hunter, Gary L. Stiegler, Patrick J. Gaines
  • Flea protease proteins and uses thereof
    Patent number: 6150125
    Abstract: The present invention relates to flea serine protease proteins, aminopeptidase proteins and flea cysteine protease proteins; to flea serine protease, aminopeptidase and cysteine protease nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins; and to compounds that inhibit flea serine protease, aminopeptidase and/or cysteine protease activities. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitors. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies, and/or inhibitors as well as the use of such therapeutic compositions to protect a host animal from flea infestation.
    Type: Grant
    Filed: April 24, 1996
    Date of Patent: November 21, 2000
    Assignee: Heska Corporation
    Inventors: Robert B. Grieve, Keith E. Rushlow, Shirley Wu Hunter, Glenn R. Frank, Gary L. Stiegler, Patrick J. Gaines, Gary Silver