Patents by Inventor Patrick J. Stover

Patrick J. Stover has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABLE PRO-VITAMIN DERIVATIVE COMPOUNDS, PHARMACEUTICAL AND DIETARY COMPOSITIONS, AND METHODS OF THEIR USE
    Publication number: 20190298721
    Abstract: The present invention relates to a compound of Formula I: [Formula should be inserted here], where R1, R2, and n are as described above, and pharmaceutically acceptable salts and solvates thereof. The present invention also relates to use of the above-noted compounds and compositions including those compounds.
    Type: Application
    Filed: July 6, 2017
    Publication date: October 3, 2019
    Inventors: Patrick J. STOVER, Martha S. FIELD
  • Use of uridine and deoxyuridine to treat folate-responsive pathologies
    Patent number: 9579337
    Abstract: The present invention relates to a pharmaceutical or dietary composition comprising deoxyuridine and a pharmaceutically or dietetically suitable carrier. Another aspect of the present invention relates to a method of supplementing the dietary needs of a subject. This method includes administering to the subject a dietary supplementing effective amount of deoxyuridine. Yet another aspect of the present invention relates to a method of treating cancer in a subject. This method includes selecting a subject having cancer and administering to the selected subject a therapeutically effective amount of uridine, thereby treating the cancer in the selected subject.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: February 28, 2017
    Assignee: Cornell University
    Inventors: Patrick J. Stover, Martha S. Field
  • USE OF URIDINE AND DEOXYURIDINE TO TREAT FOLATE-RESPONSIVE PATHOLOGIES
    Publication number: 20140080784
    Abstract: The present invention relates to a pharmaceutical or dietary composition comprising deoxyuridine and a pharmaceutically or dietetically suitable carrier. Another aspect of the present invention relates to a method of supplementing the dietary needs of a subject. This method includes administering to the subject a dietary supplementing effective amount of deoxyuridine. Yet another aspect of the present invention relates to a method of treating cancer in a subject. This method includes selecting a subject having cancer and administering to the selected subject a therapeutically effective amount of uridine, thereby treating the cancer in the selected subject.
    Type: Application
    Filed: April 25, 2012
    Publication date: March 20, 2014
    Applicant: CORNELL UNIVERSITY
    Inventors: Patrick J. Stover, Martha S. Field
  • Treatment or Prevention of Cancer or Cardiovascular Disease with Methenyltetrahydrofolate Synthetases
    Publication number: 20090005385
    Abstract: The present invention relates to a method of screening test substances for chemotherapeutic activity or for efficacy in treating cardiovascular disease by providing one or more cells transformed with a nucleic acid molecule encoding methenyltetrahydrofolate synthetase, contacting the cells with test substance(s), and identifying those test substances which modulate methenyltetrahydrofolate synthetase expression as candidates for such therapeutic use. Another aspect of the present invention relates to a method of measuring folate status in a sample by measuring methenyltetrahydrofolate synthetase expression or activity and/or catecholamine activity in the sample, all of which are correlated to folate status in the sample. The present invention can also be used to treat or prevent cancer or cardiovascular disease in a subject by administering to the subject a substance which modulates methenyltetrahydrofolate synthetase expression or activity and/or catecholamine activity.
    Type: Application
    Filed: June 13, 2005
    Publication date: January 1, 2009
    Applicant: CORNELL RESEARCH FOUNDATION, INC.
    Inventor: Patrick J. Stover