Abstract: An image processing system operable to generate one or more images for display, the system comprising a rendering unit operable to render one or more of a plurality of textures using flexible scale rasterization, FSR, a metadata generation unit operable to generate metadata indicating one or more properties of the FSR used to render a corresponding texture, a shader compiler operable to read the metadata, and to modify a shader to enable a texture sampling to be performed that includes an FSR resolve where the metadata indicates that a corresponding texture has been rendered with FSR, and an image generation unit operable to generate an image for display using at least one modified shader, the generated image including one or more of the plurality of textures.

Abstract: The invention provides antigen binding domains that bind myeloid cell surface antigen CD33 protein comprising the antigen binding domains that bind CD33, polynucleotides encoding them, vectors, host cells, methods of making and using them.

Abstract: Applicators for applying an on-skin assembly to skin of a host and methods of their use and/or manufacture are provided. An applicator includes an insertion assembly configured to insert at least a portion of the on-skin assembly into the skin of the host, a housing configured to house the insertion assembly, the housing comprising an aperture through which the on-skin assembly can pass, an actuation member configured to, upon activation, cause the insertion assembly to insert at least the portion of the on-skin assembly into the skin of the host, and a sealing element configured to provide a sterile barrier and a vapor barrier between an internal environment of the housing and an external environment of the housing.

Abstract: A system in accordance with present embodiments includes an amusement park system having one or more hardware components and a controller. The controller includes a memory device having a game layer and a software layer stored thereon. The game layer includes game logic, and the software layer includes a game API communicatively coupled to the game layer, a wrapper API communicatively coupled to the game API, and multiple wrappers communicatively coupled to the wrapper API. The controller further includes a processor configured to execute instructions to cause the processor to receive a signal indicative of a change in the hardware components, and, based on the signal indicative of the change in the hardware components, communicate with the hardware components via a wrapper to receive an input from the hardware components, or drive operation of the hardware components.

Abstract: A server or an on-premises computing node accesses a message and a destination tag indicating one or more client devices participating in a conference to receive the message. The server or the on-premises computing node determines a configuration for the message based on a source of the message. The server or the on-premises computing node transmits the message to the one or more client devices indicated in the destination tag to configure the one or more client devices to display the message according to the configuration within a display region associated with the conference.

Abstract: A server or an on-premises computing node accesses a message and a destination tag indicating one or more client devices participating in a conference to receive the message. The server or the on-premises computing node determines a configuration for the message based on a source of the message. The server or the on-premises computing node transmits the message to the one or more client devices indicated in the destination tag to configure the one or more client devices to display the message according to the configuration within a display region associated with the conference.

Abstract: Apparatus and methods for the detection of proteins in biological fluids such as urine using a label-free assay is described. Specific proteins are detected by their binding to highly specific capture reagents such as SOMAmers that are attached to the surface of a substrate. Changes to these capture reagents and their local environment upon protein binding modify the behavior of color centers (e.g., fluorescence, ionization state, spin state, etc.) embedded in the substrate beneath the bound capture reagents. These changes can be read out, for example, optically or electrically, for an individual color center or as an average response of many color centers.

Abstract: In an embodiment, a virtual reality ride system includes a display to present virtual reality image content to a first rider, an audio sensor to capture audio data associated with a second rider, and an image sensor to capture image data associated with the second rider. The virtual reality ride system also includes at least one processor communicatively coupled to the display and configured to (i) receive the audio data, the image data, or both, (ii) generate a virtual avatar corresponding to the second rider, wherein the virtual avatar includes a set of facial features, (iii) update the set of facial features based on the audio data, the image data, or both, and (iv) instruct the display to present the virtual reality image content including the virtual avatar and the updated set of facial features.

Abstract: Determining location of a mobile device includes determining the proximity of the mobile device to a predetermined location. Based on the proximity determination, a locational accuracy criterion is selected and the location of the mobile device is determined according to the selected locational accuracy criterion.

Abstract: A dissolvable medical device for protecting a corneal surface and providing lubrication and hydration to the corneal surface during ophthalmic surgery comprising: a polymeric film has sufficient dimensions to substantially cover a cornea when applied to an eye, wherein the polymeric film comprising one or more mucoadhesive polymers. The polymeric film dissolves between 15 minutes to 120 minutes to release the mucoadhesive polymers after applying the polymeric film to the eye and the polymeric film provides more effective corneal surface protection relative to a saline treatment based on Mean Green Fluorescence Index test (demonstrates corneal damage) during a simulated surgery. In addition, a kit for use in ophthalmic surgical procedures comprises 1) the at least one dissolvable medical device and 2) at least one viscosurgical viscoelastic or at least one ophthalmoscopic surgical contact lens.

Abstract: Efficient two-way communications using broadband cellular technology is provided by adapting cellular components for end-to-end Internet Protocol (IP) addressable traffic. In this manner, the broadband cellular system may be efficiently transfer data over a flat network architecture using end-to-end IP traffic, bypassing features such as network address translation (NAT), tunnelling, and other LTE cellular carrier features.

Abstract: Systems and methods for conducting surface-mediated chemical and/or biochemical reactions within an enclosed chamber are disclosed. Systems and methods of the present disclosure may be used in conducting hybridization reactions of biopolymers. In some examples, an improved method for mixing thin films of solutions in a hybridization chamber includes altering the direction of mixing at least once over the course of a reaction. In some examples, an improved method for mixing thin films of solutions in a hybridization chamber includes altering the speed of mixing at least once over the course of a reaction. In some examples, an improved method for mixing thin films of solutions in a hybridization chamber includes altering the speed of mixing and the direction of mixing at least once over the course of a reaction.

Abstract: A content processing system for an amusement park attraction includes a processor configured to receive a data stream including one or more control instructions for output of amusement content. The processor is also configured to identify one or more operational characteristics of an accessory. The processor is also configured to, based on the one or more operational characteristics, effectuate modification of the data stream to generate a modified data stream including one or more updated control instructions for output of adjusted amusement content to be presented to a user via the accessory. The processor is also configured to transmit the modified data stream to the accessory.

Abstract: Positional communication systems and methods include receiving a definition of a first geographic area including a first commercial location by a computer system and storing the first geographic area in a memory. The location of a mobile device in the possession of a customer is determined, and if the mobile device is determined to be at a location within the first geographic area, an incentive message for the customer to leave the location and go to a second commercial location is sent to the mobile device.

Abstract: A quick disconnect system for an accessory electrically coupled to a component of an amusement attraction includes a multi-part electrical enclosure including a first side, a second side opposite the first side, a first opening on the first side, and a relief pass through. The multi-part electrical enclosure is configured to: have a first electrical cable coupled to the accessory pass into the multi-part electrical enclosure via the first opening and have a second electrical cable pass into the second side of the multi-part electrical enclosure to enable the first and second cables to be coupled together within the multi-part electrical enclosure. The relief pass through is configured to provide strain relief to both the first electrical cable and the second electrical cable and to prevent disconnection of the accessory from the multi-part electrical enclosure.

Abstract: Applicators for applying an on-skin assembly to skin of a host and methods of their use and/or manufacture are provided. An applicator includes an insertion assembly configured to insert at least a portion of the on-skin assembly into the skin of the host, a housing configured to house the insertion assembly, the housing comprising an aperture through which the on-skin assembly can pass, an actuation member configured to, upon activation, cause the insertion assembly to insert at least the portion of the on-skin assembly into the skin of the host, and a sealing element configured to provide a sterile barrier and a vapor barrier between an internal environment of the housing and an external environment of the housing.

Abstract: A first service of a provider network obtains an identification of one or more substrate addressable devices included in an extension of the provider network. Based on the identification, a launch of one or more compute instances within the provider network is initiated. The one or more compute instances are to connect the provider network to the extension of the provider network across at least a third-party network by receiving a first control plane message directed to a first substrate addressable device of the one or more substrate addressable devices, by updating a message state data store based at least in part on the first control plane message, and by sending a second control plane message to the first substrate addressable device via a secure tunnel.

Abstract: Applicators for applying an on-skin assembly to skin of a host and methods of their use and/or manufacture are provided. An applicator includes an insertion assembly configured to insert at least a portion of the on-skin assembly into the skin of the host, a housing configured to house the insertion assembly, the housing comprising an aperture through which the on-skin assembly can pass, an actuation member configured to, upon activation, cause the insertion assembly to insert at least the portion of the on-skin assembly into the skin of the host, and a sealing element configured to provide a sterile barrier and a vapor barrier between an internal environment of the housing and an external environment of the housing.

Abstract: A drain cleaner is disclosed having a housing with an interior region for storing a flexible drain cleaning cable. The drain cleaning cable can be extended from the drain cleaner and includes a rotatable member within a non-rotating sheath. The drain cleaner includes an engageable drive shaft coupled to the rotatable member. In certain versions, the drive shaft is coupled to the rotatable member through a torque limiting device such as a clutch. Upon engagement of the drive shaft with a rotary power source, a rotating distal end of the flexible cable can be used to dislodge obstructions in pipes. The interior region of the drain cleaner is configured to promote efficient coiling of the drain cleaning cable. The drain cleaner includes additional features for reducing wear of cable and components, and securely retaining the cable to the drain cleaner.

Abstract: A location system for locating workers including a plurality of light detectors mounted at known locations and configured to detect light from one or more workers, and a processing system configured to determine locations of the workers using the light detected by the light detectors. There is also disclosed a wearable device for locating a worker including a wireless transceiver, and a wearable device light source and/or one or more reflective elements. There is also disclosed a method for locating workers including detecting light from one or more workers using a plurality of light detectors mounted at known locations, and determining locations of the workers using the light detected by the light detectors.