Patents by Inventor Patrick Kaltenbach
Patrick Kaltenbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8277761Abstract: A fluidic device (100) comprising a substrate (101) and a transport medium (103) provided on the substrate (101) to define a transport path for transporting a fluidic sample (104) driven by an electric force.Type: GrantFiled: August 3, 2006Date of Patent: October 2, 2012Assignee: Agilent Technologies, Inc.Inventors: Stefan Falk-Jordan, Patrick Kaltenbach
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Publication number: 20090266713Abstract: A fluidic device (100) comprising a substrate (101) and a transport medium (103) provided on the substrate (101) to define a transport path for transporting a fluidic sample (104) driven by an electric force.Type: ApplicationFiled: August 3, 2006Publication date: October 29, 2009Applicant: AGILENT TECHNOLOGIES, INC.Inventors: Stefan Falk-Jordan, Patrick Kaltenbach
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Publication number: 20090201035Abstract: A contactless detection cell (1) for detecting an electrical property of one or more sample compounds in a flow path is described. The contactless detection cell (1) comprises a transmitter electrode (3) adapted for capacitively coupling an AC current into a detection channel (4) of the flow path, and a receiver electrode (5) adapted for receiving the AC current that has been coupled into the detection channel (4). An inner cross-section (IDDET) in at least a section of the detection channel is different than an inner cross-section (IDSEP) of the flow path (2) towards the detection channel (4).Type: ApplicationFiled: June 7, 2004Publication date: August 13, 2009Inventors: Patrick Kaltenbach, Klaus Witt, Bohuslav Gas, Tom Van De Goor
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Patent number: 7449096Abstract: In a system for operation or handling of a laboratory microchip (41) for chemical processing or analysis, the microchip (41) is mounted in a first physical unit (42). The microchip (41) is arranged on a mounting plate, such that it is readily accessible from the top and thus the fitting and removal of the microchip is considerably simplified. Furthermore, the first physical unit (42) comprises an optical device (43) for contactless detection of the results of the chemical processes conducted on the microchip. The supply systems necessary for the operation of the microchip are arranged in a module unit that has a separable connection with a second physical unit. The proposed modular layout enables ease of interchangeability of the required supply systems and thus, overall, ease of adaptability of the proposed system for various types of microchips.Type: GrantFiled: August 11, 2004Date of Patent: November 11, 2008Inventors: Manfred Berndt, Patrick Kaltenbach, Colin B. Kennedy
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Publication number: 20050158875Abstract: A liquid transfer appliance and a well plate are moved towards each other and a current is detected that flows upon contact between the liquid transfer appliance and a first electrically conductive element of the well plate. The position of the well plate relative to the liquid transfer appliance is determined at the time of contact. The determined position is used as a reference position for further positioning at least one of the well plate and the liquid transfer appliance.Type: ApplicationFiled: January 18, 2005Publication date: July 21, 2005Inventors: Patrick Kaltenbach, Konstantin Choikhet, Gerhard Ple, Clemens Linowski
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Publication number: 20050011764Abstract: In a system for operation or handling of a laboratory microchip (41) for chemical processing or analysis, the microchip (41) is mounted in a first physical unit (42). The microchip (41) is arranged on a mounting plate, such that it is readily accessible from the top and thus the fitting and removal of the microchip is considerably simplified. Furthermore, the first physical unit (42) comprises an optical device (43) for contactless detection of the results of the chemical processes conducted on the microchip. The supply systems necessary for the operation of the microchip are arranged in a module unit that has a separable connection with a second physical unit. The proposed modular layout enables ease of interchangeability of the required supply systems and thus, overall, ease of adaptability of the proposed system for various types of microchips.Type: ApplicationFiled: August 11, 2004Publication date: January 20, 2005Applicants: Caliper Life Sciences, Inc., Agilent Technologies, Inc.Inventors: Manfred Berndt, Patrick Kaltenbach, Colin Kennedy
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Patent number: 6811668Abstract: In a system for operation or handling of a laboratory microchip (41) for chemical processing or analysis, the microchip (41) is mounted in a first physical unit (42). The microchip (41) is arranged on a mounting plate, such that it is readily accessible from the top and thus the fitting and removal of the microchip is considerably simplified. Furthermore, the first physical unit (42) comprises an optical device (43) for contactless detection of the results of the chemical processes conducted on the microchip. The supply systems necessary for the operation of the microchip are arranged in a module unit that has a separable connection with a second physical unit. The proposed modular layout enables ease of interchangeability of the required supply systems and thus, overall, ease of adaptability of the proposed system for various types of microchips.Type: GrantFiled: June 15, 2000Date of Patent: November 2, 2004Assignee: Caliper Life Sciences, Inc.Inventors: Manfred Berndt, Patrick Kaltenbach, Colin B. Kennedy
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Publication number: 20040141884Abstract: Microfluidic devices and systems that include keying, registration or indication elements that communicate a functionality of the microfluidic device to the instrumentation which is used in conjunction with these devices. Indicator elements include structural indicators, electrical indicators, optical indicators and chemical indicators. Different indicator elements are indicative of different functionalities, e.g., applications, new vs. used, and the like.Type: ApplicationFiled: November 5, 2003Publication date: July 22, 2004Applicants: Caliper Technologies Corp., Agilent Technologies Inc.Inventors: Garrett Unno, Colin B. Kennedy, Patrick Kaltenbach, Manfred Berndt
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Patent number: 6759013Abstract: A modular microchannel apparatus for analysis of an analyte. The apparatus includes a separation unit and a reservoir unit. The separation unit has a microchannel. The analyte can be driven to pass through the microchannel such that the time for the analyte to pass through the microchannel is indicative of the molecular characteristics of the analyte. The reservoir unit has one or more reservoirs for coupling operatively modularly with the separation unit to supply liquid reagents to the separation unit. The reservoirs has prepackaged liquid reagents in it before the reservoir unit is coupled with the separation unit.Type: GrantFiled: September 17, 1998Date of Patent: July 6, 2004Assignee: Agilent Technologies, Inc.Inventors: Patrick Kaltenbach, Tom A. van de Goor
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Publication number: 20030021725Abstract: Microfluidic devices and systems that include keying, registration or indication elements that communicate a functionality of the microfluidic device to the instrumentation which is used in conjunction with these devices. Indicator elements include structural indicators, electrical indicators, optical indicators and chemical indicators. Different indicator elements are indicative of different functionalities, e.g., applications, new vs. used, and the like.Type: ApplicationFiled: August 8, 2002Publication date: January 30, 2003Applicant: Caliper Technologies Corp.Inventors: Garrett Unno, Colin B. Kennedy, Patrick Kaltenbach, Manfred Berndt
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Patent number: 6504607Abstract: Systems and methods for analyzing a sample are disclosed. The system may include a light source operable to transmit light onto the sample, a detector operable to detect intensity of the light emitted from the sample, and a power modulator. The power modulator modulates the light source power such that light is emitted from the light source in more than one mode to reduce changes in the emitted light due to temperature changes in the light source.Type: GrantFiled: December 4, 2001Date of Patent: January 7, 2003Assignees: Caliper Technologies, Corp., Agilent Technologies Inc.Inventors: Morten J. Jensen, Patrick Kaltenbach, Volker Brombacher
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Patent number: 6495104Abstract: Microfluidic devices and systems that include keying, registration or indication elements that communicate a functionality of the microfluidic device to the instrumentation which is used in conjunction with these devices. Indicator elements include structural indicators, electrical indicators, optical indicators and chemical indicators. Different indicator elements are indicative of different functionalities, e.g., applications, new vs. used, and the like.Type: GrantFiled: August 19, 1999Date of Patent: December 17, 2002Assignee: Caliper Technologies Corp.Inventors: Garrett Unno, Colin B. Kennedy, Patrick Kaltenbach, Manfred Berndt
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Patent number: 6489774Abstract: A miniaturized ion analysis system with a contactless conductivity detection means is described for use in liquid phase sample analysis and detection. The device is formed by microfabrication of microstructures in novel support substrates. The detection means can be fabricated directly in the support body at the point of detection or other locations on the device or, alternatively, may be formed as part of a modular structure that is insertable into the device at the point of detection. In addition, a method is provided for analyzing ionic species present in a sample using the miniaturized ion analysis device. The invention herein is used for the analysis of ionic solutes in the liquid phase.Type: GrantFiled: July 8, 1999Date of Patent: December 3, 2002Assignee: Agilent Technologies, Inc.Inventors: Tom A van de Goor, Patrick Kaltenbach
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Publication number: 20020041375Abstract: Systems and methods for analyzing a sample are disclosed. The system may include a light source operable to transmit light onto the sample, a detector operable to detect intensity of the light emitted from the sample, and a power modulator. The power modulator modulates the light source power such that light is emitted from the light source in more than one mode to reduce changes in the emitted light due to temperature changes in the light source.Type: ApplicationFiled: December 4, 2001Publication date: April 11, 2002Inventors: Morten J. Jensen, Patrick Kaltenbach, Volker Brombacher
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Patent number: 6353475Abstract: Systems and methods for analyzing a sample are disclosed. The system may include a light source operable to transmit light onto the sample, a detector operable to detect intensity of the light emitted from the sample, and a power modulator. The power modulator modulates the light source power such that light is emitted from the light source in more than one mode to reduce changes in the emitted light due to temperature changes in the light source.Type: GrantFiled: August 19, 1999Date of Patent: March 5, 2002Assignees: Caliper Technologies Corp., Agilent Technologies Inc.Inventors: Morten J. Jensen, Patrick Kaltenbach, Volker Brombacher
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Patent number: 6264892Abstract: Miniaturized planar column devices for use in a liquid phase separation apparatus are described. The devices include microstructures that have been fabricated by laser ablation in a variety of novel support substrates. Devices formed according to the methods of the invention include associated laser-ablated features required for function, such as on-device reservoirs or makeup flow compartments, analyte detection means and sample injection means. The miniaturized columns can be used in an apparatus intended for analysis of either small and/or macromolecular solutes in the liquid phase which employs chromatographic, electrophoretic or electrochromatographic separation means. The apparatus can include a variety of optional injection means, manifolds, keeper means, post column collection means, and combinations thereof.Type: GrantFiled: January 11, 2000Date of Patent: July 24, 2001Assignee: Agilent Technologies, Inc.Inventors: Patrick Kaltenbach, Sally A. Swedberg, Klaus E. Witt, Fritz Bek, Laurie S. Mittelstadt
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Publication number: 20010008613Abstract: A modular microchannel apparatus for analysis of an analyte. The apparatus includes a separation unit and a reservoir unit. The separation unit has a microchannel. The analyte can be driven to pass through the microchannel such that the time for the analyte to pass through the microchannel is indicative of the molecular characteristics of the analyte. The reservoir unit has one or more reservoirs for coupling operatively modularly with the separation unit to supply liquid reagents to the separation unit. The reservoirs has prepackaged liquid reagents in it before the reservoir unit is coupled with the separation unit.Type: ApplicationFiled: September 17, 1998Publication date: July 19, 2001Applicant: AGILENT TECHNOLOGIESInventors: PATRICK KALTENBACH, TOM A. VAN DE GOOR
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Patent number: 6254754Abstract: A chip for performing an electrophoretic separation of micromolecular or macromolecular structures in two dimensions comprises a base substrate comprising a main surface. A channel is formed in the main surface of said base substrate in a first direction, wherein a first voltage is applicable across the channel in order to allow a separation of micromolecular structures or macromolecular structures in the first direction on the basis of a first separation mechanism. In addition, a two-dimensional separation matrix is formed in the main surface of the base substrate, wherein the separation matrix comprises a shallow recess and an array of stand-alone posts arranged in the recess. The recess extends perpendicular from the channel in a second direction, wherein a second voltage is applicable across the separation matrix in order to allow a separation of the structures on the basis of a second separation mechanism.Type: GrantFiled: July 26, 1999Date of Patent: July 3, 2001Assignee: Agilent Technologies, Inc.Inventors: Gordon Ross, Patrick Kaltenbach
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Patent number: 6093362Abstract: Miniaturized planar column devices are described for use in liquid phase analysis, the devices comprising microstructures fabricated by laser ablation in a variety of novel support substrates. Devices formed according to the invention include associated laser-ablated features required for function, such as analyte detection means and fluid communication means. Miniaturized columns constructed under the invention find use in any analysis system performed on either small and/or macromolecular solutes in the liquid phase and may employ chromatographic, electrophoretic, electrochromatographic separation means, or any combination thereof.Type: GrantFiled: February 11, 1999Date of Patent: July 25, 2000Assignee: Agilent Technologies, Inc.Inventors: Patrick Kaltenbach, Sally A. Swedberg, Klaus E. Witt, Fritz Bek, Laurie S. Mittelstadt
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Patent number: 6033628Abstract: In a method of forming a microchannel and/or microcavity structure by bonding together two elements (1, 2) having opposed plane surfaces of the same or different material, one or both surfaces having open channels and/or cavities, bonding is effected by applying to one or both element surfaces (1, 2) a thin layer (3) of a solution of a material capable of fusing with and having a lower melting point than that of the material or materials of the two element surfaces (1, 2) in a solvent which substantially does not dissolve the element surface material or materials. The solvent is then removed, and the two elements (1, 2) are brought together and heated to a temperature where the dissolved material is caused to melt but not the element surface material or materials.Type: GrantFiled: April 27, 1998Date of Patent: March 7, 2000Assignee: Agilent Technologies, Inc.Inventors: Patrick Kaltenbach, Sally A. Swedberg, Klaus E. Witt, Fritz Bek, Laurie S. Mittelstadt