Patents by Inventor Patrick Kaminker

Patrick Kaminker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATMENT USING A BISPECIFIC ANTIGEN-BINDING CONSTRUCT TARGETING HER2
    Publication number: 20260022193
    Abstract: Described herein is a method of treating a HER2-positive gastroesophageal adenocarcinoma (GEA) comprising administering a bispecific antigen-binding construct targeting HER2 to a subject.
    Type: Application
    Filed: October 2, 2025
    Publication date: January 22, 2026
    Inventors: Diana F. Hausman, Neil C. Josephson, Rose Kamyee Lai, Gerald James Rowse, Patrick Kaminker
  • Methods of using a bispecific antigen-binding construct targeting HER2 for the treatment of biliary tract cancers
    Patent number: 12435157
    Abstract: Described herein is a method of treating biliary tract cancer (BTC) comprising administering a bispecific antigen-binding construct targeting HER2 or a bispecific antigen-binding construct targeting HER2 linked to an auristatin analogue (ADC) to a subject.
    Type: Grant
    Filed: November 19, 2021
    Date of Patent: October 7, 2025
    Assignee: ZYMEWORKS BC INC.
    Inventors: Diana F. Hausman, Neil C. Josephson, Rose Kamyee Lai, Gerald James Rowse, Patrick Kaminker
  • METHODS OF USING A BISPECIFIC ANTIGEN-BINDING CONSTRUCT TARGETING HER2 IN COMBINATION WITH CDK4/6 INHIBITORS FOR THE TREATMENT OF BREAST CANCER
    Publication number: 20250009788
    Abstract: Described herein is a method of treating breast cancer comprising administering a bispecific antigen-binding construct targeting HER2 or a bispecific antigen-binding construct targeting HER2 linked to an auristatin analogue (ADC) in combination with a CDK4/6 inhibitor to a subject.
    Type: Application
    Filed: July 23, 2024
    Publication date: January 9, 2025
    Inventors: Nina E. Weisser, Diana F. Hausman, Patrick Kaminker
  • Methods of using a bispecific antigen-binding construct targeting HER2 in combination with CDK4/6 inhibitors for the treatment of breast cancer
    Patent number: 12076400
    Abstract: Described herein is a method of treating breast cancer comprising administering a bispecific antigen-binding construct targeting HER2 or a bispecific antigen-binding construct targeting HER2 linked to an auristatin analogue (ADC) in combination with a CDK4/6 inhibitor to a subject.
    Type: Grant
    Filed: May 29, 2020
    Date of Patent: September 3, 2024
    Assignee: Zymeworks BC Inc.
    Inventors: Nina E. Weisser, Diana F. Hausman, Patrick Kaminker
  • METHODS OF USING A BISPECIFIC ANTIGEN-BINDING CONSTRUCT TARGETING HER2 FOR THE TREATMENT OF BILIARY TRACT CANCERS
    Publication number: 20220133903
    Abstract: Described herein is a method of treating biliary tract cancer (BTC) comprising administering a bispecific antigen-binding construct targeting HER2 or a bispecific antigen-binding construct targeting HER2 linked to an auristatin analogue (ADC) to a subject.
    Type: Application
    Filed: November 19, 2021
    Publication date: May 5, 2022
    Inventors: Diana F. Hausman, Neil C. Josephson, Rose Kamyee Lai, Gerald James Rowse, Patrick Kaminker
  • METHODS OF USING A BISPECIFIC ANTIGEN-BINDING CONSTRUCT TARGETING HER2 IN COMBINATION WITH CDK4/6 INHIBITORS FOR THE TREATMENT OF BREAST CANCER
    Publication number: 20210170023
    Abstract: Described herein is a method of treating breast cancer comprising administering a bispecific antigen-binding construct targeting HER2 or a bispecific antigen-binding construct targeting HER2 linked to an auristatin analogue (ADC) in combination with a CDK4/6 inhibitor to a subject.
    Type: Application
    Filed: May 29, 2020
    Publication date: June 10, 2021
    Inventors: Nina E. Weisser, Diana F. Hausman, Patrick Kaminker
  • Method for analyzing molecular expression or function in an intact single cell
    Patent number: 6420105
    Abstract: A method for obtaining molecules from a substantially intact single cell is disclosed. The method differs from prior methods that obtain a variable fraction of a cell's contents and therefore cannot quantitatively estimate the number of molecules in the cells. The present method comprises isolating and harvesting a substantially intact single cell from its organ tissue comprising the steps of subjecting a tissue mass to a dissociation method so that the cells are dissociated from the tissue to expose cell bodies or cell processes, contacting a dissociated cell with a device capable of collecting the cell from the tissue substantially intact, withdrawing device with the cell attached, and then isolating or detecting the molecules in the single cell.
    Type: Grant
    Filed: July 27, 2000
    Date of Patent: July 16, 2002
    Assignee: University of Kentucky Research Foundation
    Inventors: Philip W. Landfield, Olivier Thibault, Eric Blalock, Kuey-Chu Chen, Patrick Kaminker