Abstract: A mandrel for holding and positioning an intraocular lens blank during manufacturing includes a shank portion having a central axis and a lens blank holding section configured to hold the lens blank. The holding section includes a central cavity formed concentrically with the central axis of the mandrel. Projections are formed on a surface of the central cavity and are configured to support a first surface of the lens blank at a fixed distance from the surface of the central cavity. A ring fits within a peripheral portion of the central cavity to hold a second opposing surface of the lens blank. A method for making an intraocular lens using the mandrel includes filling the space formed under the first surface of the lens with a liquid, such as water, freezing the liquid, and then machining and/or milling the second surface of the lens blank.

Abstract: An implantable wireless lead includes an enclosure, the enclosure housing: one or more electrodes configured to apply one or more electrical pulses to a neural tissue; a first antenna configured to: receive, from a second antenna and through electrical radiative coupling, an input signal containing electrical energy, the second antenna being physically separate from the implantable neural stimulator lead; one or more circuits electrically connected to the first antenna, the circuits configured to: create the one or more electrical pulses suitable for stimulation of the neural tissue using the electrical energy contained in the input signal; and supply the one or more electrical pulses to the one or more electrodes, wherein the enclosure is shaped and arranged for delivery into a subject's body through an introducer or a needle.

Abstract: Implementations provide a method that includes: placing a controller device over a surface region of the patient where the implantable wireless stimulation device has been implanted; configuring the controller device to (i) monitor a return loss representing electrical power reflected from the implantable wireless stimulation device to the controller device; (ii) compute a first path loss metric based on a first monitored return loss when the controller device is place over a first location within the surface region; (iii) compute a second path loss metric based on a second monitored return loss when the controller device is over a second location within the surface region; and (iv) generate a feedback to an operator to indicate whether the second path loss is smaller than the first path loss such that the controller device is placed at a location with more electrical energy non-inductively transferred to the implantable wireless stimulation device.

Abstract: Implementations provide a method that includes: placing a controller device over a surface region of the patient where the implantable wireless stimulation device has been implanted; configuring the controller device to (i) monitor a return loss representing electrical power reflected from the implantable wireless stimulation device to the controller device; (ii) compute a first path loss metric based on a first monitored return loss when the controller device is place over a first location within the surface region; (iii) compute a second path loss metric based on a second monitored return loss when the controller device is over a second location within the surface region; and (iv) generate a feedback to an operator to indicate whether the second path loss is smaller than the first path loss such that the controller device is placed at a location with more electrical energy non-inductively transferred to the implantable wireless stimulation device.

Abstract: A method, system, and apparatus for temporarily modifying an impedance of a neural stimulator. The apparatus includes an antenna comprising a first pole and a second pole, a switching circuit configured to output switched signals, a rectifier configured to receive switched signals from the switching circuit, a plurality of electrodes, and a controller, wherein the switching circuit, based on the control signal, modifies one or more of a first pole signal or a second pole signal. The impedance may be modified via one or more switches in a switching circuit of the neural stimulator. The impedance change may be sensed by an external circuit. Also, an electrode-tissue impedance of the neural stimulator may be determined and an impedance of an external circuit modified based on the electrode-tissue impedance of the neural stimulator.

Abstract: An implantable electronic device includes a flexible circuit board, one or more circuit components attached to the flexible circuit board and configured to convert electrical energy into electrical pulses, and one or more electrodes attached to the flexible circuit board without cables connecting the electrodes to each other or to the flexible circuit board, the one or more electrodes configured to apply the electrical pulses to a tissue adjacent the implantable electronic device.

Abstract: Implementations provide a method that includes: placing a controller device over a surface region of the patient where the implantable wireless stimulation device has been implanted; configuring the controller device to (i) monitor a return loss representing electrical power reflected from the implantable wireless stimulation device to the controller device; (ii) compute a first path loss metric based on a first monitored return loss when the controller device is place over a first location within the surface region; (iii) compute a second path loss metric based on a second monitored return loss when the controller device is over a second location within the surface region; and (iv) generate a feedback to an operator to indicate whether the second path loss is smaller than the first path loss such that the controller device is placed at a location with more electrical energy non-inductively transferred to the implantable wireless stimulation device.

Abstract: An implantable electronic device includes a flexible circuit board, one or more circuit components attached to the flexible circuit board and configured to convert electrical energy into electrical pulses, and one or more electrodes attached to the flexible circuit board without cables connecting the electrodes to each other or to the flexible circuit board, the one or more electrodes configured to apply the electrical pulses to a tissue adjacent the implantable electronic device.

Abstract: A medical apparatus includes a tubular shaped enclosure configured for implantation into a tissue medium; a receiver array with a multitude of receiver elements housed within the enclosure attached to the associated electronics via a flexible circuit board construction, wherein the receiver array is configured to receive one or more electromagnetic input signals of a combination of both power and data from an external transmitter via non-inductive coupling energy transfer, wherein the receiver array is composed of multiple receiver elements, wherein each receiver element within the receiver array includes an electrically small antenna and one or more processor circuits connected to the port of the antenna on the same physical substrate, wherein the receiver array and associated flexible circuit board are directly attached to two or more electrodes that are in direct contact with biological tissue for the purpose of transmitting stimulation pulses to tissue.

Abstract: A method includes: transmitting a first set of radio-frequency (RF) pulses to an implantable wireless stimulator device such that electric currents are created from the first set of RF pulses and flown through a calibrated internal load on the implantable wireless stimulator device; in response to the electric currents flown through a calibrated internal load, recording a first set of RF reflection measurements; transmitting a second set of radio-frequency (RF) pulses to the implantable wireless stimulator device such that stimulation currents are created from the second set of RF pulses and flown through an electrode of the implantable wireless stimulator device to tissue surrounding the electrode; in response to the stimulation currents flown through the electrode to the surrounding tissue, recording a second set of RF reflection measurements; and characterizing an electrode-tissue impedance by comparing the second set of RF reflection measurements with the first set of RF reflections measurements.

Abstract: Implementations provide a method that includes: placing a controller device over a surface region of the patient where the implantable wireless stimulation device has been implanted; configuring the controller device to (i) monitor a return loss representing electrical power reflected from the implantable wireless stimulation device to the controller device; (ii) compute a first path loss metric based on a first monitored return loss when the controller device is place over a first location within the surface region; (iii) compute a second path loss metric based on a second monitored return loss when the controller device is over a second location within the surface region; and (iv) generate a feedback to an operator to indicate whether the second path loss is smaller than the first path loss such that the controller device is placed at a location with more electrical energy non-inductively transferred to the implantable wireless stimulation device.

Abstract: A system includes a controller module, which includes a storage device, a controller, a modulator, and one or more antennas. The storage device is stored with parameters defining a stimulation waveform. The controller is configured to generate, based on the stored parameters, an output signal that includes the stimulation waveform, wherein the output signal additionally includes polarity assignments for electrodes in an implantable, passive stimulation device. The modulator modulates a stimulus carrier signal with the output signal to generate a transmission signal.

Abstract: A system, including: an implantable neural stimulator including electrodes, at least one antenna and an electrode interface; a radio-frequency (RF) pulse generator module comprising an antenna module configured to send an input signal to the antenna in the implantable neural stimulator through electrical radiative coupling, the input signal containing electrical energy and polarity assignment information that designates polarity assignments of the electrodes in the implantable neural stimulator; and wherein the implantable neural stimulator is configured to: control the electrode interface such that the electrodes have the polarity assignments designated by the polarity assignment information, create one or more electrical pulses suitable for modulation of neural tissue using the electrical energy contained in the input signal, and supply the electrical pulses to the electrodes through the electrode interface such that the electrodes apply the electrical pulses to the neural tissue with the polarity assignmen

Abstract: An implantable wireless lead includes an enclosure, the enclosure housing: one or more electrodes configured to apply one or more electrical pulses to a neural tissue; a first antenna configured to: receive, from a second antenna and through electrical radiative coupling, an input signal containing electrical energy, the second antenna being physically separate from the implantable neural stimulator lead; one or more circuits electrically connected to the first antenna, the circuits configured to: create the one or more electrical pulses suitable for stimulation of the neural tissue using the electrical energy contained in the input signal; and supply the one or more electrical pulses to the one or more electrodes, wherein the enclosure is shaped and arranged for delivery into a subject's body through an introducer or a needle.

Abstract: An implantable wireless lead includes an enclosure, the enclosure housing: one or more electrodes configured to apply one or more electrical pulses to a neural tissue; a first antenna configured to: receive, from a second antenna and through electrical radiative coupling, an input signal containing electrical energy, the second antenna being physically separate from the implantable neural stimulator lead; one or more circuits electrically connected to the first antenna, the circuits configured to: create the one or more electrical pulses suitable for stimulation of the neural tissue using the electrical energy contained in the input signal; and supply the one or more electrical pulses to the one or more electrodes, wherein the enclosure is shaped and arranged for delivery into a subject's body through an introducer or a needle.

Abstract: Some implementations provide a method for modulating excitable tissue in a body of a patient, the method including: placing a wireless implantable stimulator device at a target site in the patient's body, the stimulator device including one or more electrodes; reconfiguring the wireless implantable stimulator device to form an enclosure that substantially surrounds the excitable tissue at the target site with the electrodes on the inside of the enclosure and facing the nerve; and causing electrical impulses to be delivered to the electrodes on the wireless implantable stimulator device such that neural modulation is applied to the excitable tissue substantially surrounded by the enclosure.

Abstract: An implantable electronic device includes a flexible circuit board, one or more circuit components attached to the flexible circuit board and configured to convert electrical energy into electrical pulses, and one or more electrodes attached to the flexible circuit board without cables connecting the electrodes to each other or to the flexible circuit board, the one or more electrodes configured to apply the electrical pulses to a tissue adjacent the implantable electronic device.

Abstract: A system, including: an implantable neural stimulator including electrodes, at least one antenna and an electrode interface; a radio-frequency (RF) pulse generator module comprising an antenna module configured to send an input signal to the antenna in the implantable neural stimulator through electrical radiative coupling, the input signal containing electrical energy and polarity assignment information that designates polarity assignments of the electrodes in the implantable neural stimulator; and wherein the implantable neural stimulator is configured to: control the electrode interface such that the electrodes have the polarity assignments designated by the polarity assignment information, create one or more electrical pulses suitable for modulation of neural tissue using the electrical energy contained in the input signal, and supply the electrical pulses to the electrodes through the electrode interface such that the electrodes apply the electrical pulses to the neural tissue with the polarity assignmen

Abstract: A system includes a controller module, which includes a storage device, a controller, a modulator, and one or more antennas. The storage device is stored with parameters defining a stimulation waveform. The controller is configured to generate, based on the stored parameters, an output signal that includes the stimulation waveform, wherein the output signal additionally includes polarity assignments for electrodes in an implantable, passive stimulation device. The modulator modulates a stimulus carrier signal with the output signal to generate a transmission signal.

Abstract: An implantable neural stimulator method for modulating excitable tissue in a patient including: implanting a neural stimulator within the body of the patient such that one or more electrodes of the neural stimulator are positioned at a target site adjacent to or near excitable tissue; generating an input signal with a controller module located outside of, and spaced away from, the patient's body; transmitting the input signal to the neural stimulator through electrical radiative coupling; converting the input signal to electrical pulses within the neural stimulator; and applying the electrical pulses to the excitable tissue sufficient to modulate said excitable tissue.