Abstract: Formulations and methods of manufacturing formulations for use in colonic evacuation are disclosed herein, in an embodiment, a solid dosage formulation includes an intra-granular fraction intermingled with an extra-granular fraction, wherein the intra-granular fraction includes granules comprising at least one osmotic evacuant agent, at least one antacid, and a first pharmaceutically acceptable excipient component, and wherein the extra-granular fraction includes one or more organic acids, a non-metallic lubricating element, and a second pharmaceutically acceptable excipient component.

Abstract: Formulations and methods of manufacturing formulations for use in colonic evacuation are disclosed herein, in an embodiment, a solid dosage formulation includes an intra-granular fraction intermingled with an extra-granular fraction, wherein the intra-granular fraction includes granules comprising at least one osmotic evacuant agent, at least one antacid, and a first pharmaceutically acceptable excipient component, and wherein the extra-granular fraction includes one or more organic acids, a non-metallic lubricating element, and a second pharmaceutically acceptable excipient component.

Abstract: Formulations and methods of manufacturing formulations for use in colonic evacuation are disclosed herein, in an embodiment, a solid dosage formulation includes an intra-granular fraction intermingled with an extra-granular fraction, wherein the intra-granular fraction includes granules comprising at least one osmotic evacuant agent, at least one antacid, and a first pharmaceutically acceptable excipient component, and wherein the extra-granular fraction includes one or more organic acids, a non-metallic lubricating element, and a second pharmaceutically acceptable excipient component.

Abstract: Formulations and methods of manufacturing formulations for use in colonic evacuation are disclosed herein, in an embodiment, a solid dosage formulation includes an intra-granular fraction intermingled with an extra-granular fraction, wherein the intra-granular fraction includes granules comprising at least one osmotic evacuant agent, at least one antacid, and a first pharmaceutically acceptable excipient component, and wherein the extra-granular fraction includes one or more organic acids, a non-metallic lubricating element, and a second pharmaceutically acceptable excipient component.

Abstract: Formulations and methods of manufacturing formulations for use in colonic evacuation are disclosed herein, in an embodiment, a solid dosage formulation includes an intra-granular fraction intermingled with an extra-granular fraction, wherein the intra-granular fraction includes granules comprising at least one osmotic evacuant agent, at least one antacid, and a first pharmaceutically acceptable excipient component, and wherein the extra-granular fraction includes one or more organic acids, a non-metallic lubricating element, and a second pharmaceutically acceptable excipient component.

Abstract: A combination of antibiotics including rifabutin, clarithromycin and clofazimine for the treatment of an autoimmune disease such as multiple sclerosis and related diseases. In a further aspect, there is provided a composition comprising a combination of two or more antibiotic agents for the treatment of an autoimmune disease, said two or more antibiotic agents selected from rifabutin, clofazimine, and at least one macrolide.

Abstract: Formulations and methods of manufacturing formulations for use in colonic evacuation are disclosed herein, in an embodiment, a solid dosage formulation includes an intra-granular fraction intermingled with an extra-granular fraction, wherein the intra-granular fraction includes granules comprising at least one osmotic evacuant agent, at least one antacid, and a first pharmaceutically acceptable excipient component, and wherein the extra-granular fraction includes one or more organic acids, a non-metallic lubricating element, and a second pharmaceutically acceptable excipient component.

Abstract: An interface facilitates user input of quantitatively weighted recommendations, including weighted factors in support of decision choices. A user input mechanism allows a user to specify a factor in support of a choice, and to specify values for quantitative parameters associated with the factor along two or more axes. An overall quantitative weight for the factor is generated based on the specified quantitative parameters. In one embodiment, a graphical user interface is presented, wherein the user specifies the values for the weighting parameters by dragging a movable indicator within an N-dimensional space. Each axis of the N-dimensional space corresponds to a weighting parameter. An overall quantitative weight for the factor is calculated, for example, as the product of the specified values along each of the axes. A visual indication of this calculation is presented, so as to provide an intuitive sense of the overall weight assigned to the factor.

Abstract: A combination of antibiotics including rifabutin, clarithromycin and clofazimine for the treatment of an autoimmune disease such as multiple sclerosis and related diseases. In a further aspect, there is provided a composition comprising a combination of two or more antibiotic agents for the treatment of an autoimmune disease, said two or more antibiotic agents selected from rifabutin, clofazimine, and at least one macrolide.

Abstract: An interface facilitates user input of quantitatively weighted recommendations, including weighted factors in support of decision choices. A user input mechanism allows a user to specify a factor in support of a choice, and to specify values for quantitative parameters associated with the factor along two or more axes. An overall quantitative weight for the factor is generated based on the specified quantitative parameters. In one embodiment, a graphical user interface is presented, wherein the user specifies the values for the weighting parameters by dragging a movable indicator within an N-dimensional space. Each axis of the N-dimensional space corresponds to a weighting parameter. An overall quantitative weight for the factor is calculated, for example, as the product of the specified values along each of the axes. A visual indication of this calculation is presented, so as to provide an intuitive sense of the overall weight assigned to the factor.

Abstract: An interface facilitates user input of quantitatively weighted recommendations, including weighted factors in support of decision choices. A user input mechanism allows a user to specify a factor in support of a choice, and to specify values for quantitative parameters associated with the factor along two or more axes. An overall quantitative weight for the factor is generated based on the specified quantitative parameters. In one embodiment, a graphical user interface is presented, wherein the user specifies the values for the weighting parameters by dragging a movable indicator within an N-dimensional space. Each axis of the N-dimensional space corresponds to a weighting parameter. An overall quantitative weight for the factor is calculated, for example, as the product of the specified values along each of the axes. A visual indication of this calculation is presented, so as to provide an intuitive sense of the overall weight assigned to the factor.

Abstract: A system and method solicit decision-making input from a large number of users in a structured manner that facilitates generation of useful recommendations. The individual seeking advice posts a request for advice in the form of a decision question, or identifies a previously posted decision question. Visitors to the website can post secondary questions that are intended to assist the advice-seeker in making the decision. For each secondary question, the user posting the question can specify which choice for the decision question is recommended by each answer to the secondary question. The user can also specify a strength for the recommendation. The advice-seeker then inputs answers to the secondary questions. The advice-seeker can indicate a relative significance value for some or all of the answers. For each secondary answer, a score is generated. Scores are totaled and the results are provided to the advice-seeker to assist in decision-making.

Abstract: An apparatus and method are provided for rapidly cooling small volumes of fluids. The apparatus includes a plurality of cooling elements each including a housing forming a sealable cooling fluid chamber which can house a cooling fluid. At least one spacer is arranged to separate opposed cooling elements and provide a separation distance between the opposed cooling elements. Each of the plurality of cooling elements is arranged to be independently separable to allow ready assembly, disassembly, and cleaning. The plurality of cooling elements can include a stack of disc-shaped cooling elements or concentric cylinders that can be situated in a container and rotated by a motor.

Abstract: A system and method solicit decision-making input from a large number of users in a structured manner that facilitates generation of useful recommendations. The individual seeking advice posts a request for advice in the form of a decision question, or identifies a previously posted decision question. Visitors to the website can post secondary questions that are intended to assist the advice-seeker in making the decision. For each secondary question, the user posting the question can specify which choice for the decision question is recommended by each answer to the secondary question. The user can also specify a strength for the recommendation. The advice-seeker then inputs answers to the secondary questions. The advice-seeker can indicate a relative significance value for some or all of the answers. For each secondary answer, a score is generated. Scores are totaled and the results are provided to the advice-seeker to assist in decision-making.

Abstract: A high-load capability non-explosive cable release mechanism for retaining the adjacent ends of two cables and releasing them upon receiving a signal from a remote source. The cable release mechanism has a casing for housing two non-explosive actuators (NEAs), which also has a center bore for housing a jaw and ramp assembly. Each NEA is connected to the jaw and ramp assembly for independently operating the jaw and ramp assembly to retain or release the proximal ends of the two cables. Upon receiving the signal by any one or both of the NEAs, the jaw and ramp assembly will release the adjacent ends of the two cables from the casing.

Abstract: A decorative ornament which may be attached to a shutter, wall, door, fence or other structure typically outside a home or business to enhance the appearance of the structure or to express seasonal, holiday, scholastic or other sentiment. The decorative ornament includes an ornament mount block which removably engages the structure. An ornament body which is shaped in the configuration of a flower or other selected design is removably attached to the ornament mount block typically using brackets. In one embodiment, a hook mount spring is provided on the ornament mount block. A pair of hooks terminate respective ends of the hook mount spring for removably engaging louvers or slats on a shutter, for example, or other elements on an alternative structure. In another embodiment, the ornament mount block may be attached to the structure using fasteners such as screws.

Abstract: An improved spool assembly for non-explosive actuators used in electro-mechanical structural separation devices. The spool assembly includes two spool halves each having external surfaces and a generally flat internal surface, a unitary and integral internal member made of an electrically conductive material and having a link-wire portion and two electrical terminal portions, and an external wrap-wire wound around the two spool halves and having a connecting end connected to the link-wire portion of the unitary and integral internal member such that the wrap-wire tightly binds the two spool halves together to form a spool for retaining an external structural member.