Patents by Inventor Patrick M. F. Derkx

Patrick M. F. Derkx has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8809032
    Abstract: This invention relates to amylase polypeptides, and nucleic acids encoding the polypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically the amylases of the current invention show an altered exospecifity.
    Type: Grant
    Filed: February 1, 2008
    Date of Patent: August 19, 2014
    Assignee: Dupont Nutrition Biosciences Aps
    Inventors: Casper Tune Berg, Kirsten Bojsen, Patrick M. F. Derkx, Carol Fioresi, Gijsbert Gerritse, Karsten Matthias Kragh, Wei Liu, Andrew Shaw, Charlotte Refdahl Thoudahl, Anja Hemmingsen Kellett-Smith
  • Patent number: 8143048
    Abstract: This invention relates to amylase polypeptides, and nucleic acids encoding the polpypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered exospecifity.
    Type: Grant
    Filed: July 7, 2004
    Date of Patent: March 27, 2012
    Assignee: Danisco A/S
    Inventors: Karsten Matthias Kragh, Kirsten Bojsen, Casper Tune Berg, Patrick M. F. Derkx, Anja H. Kellett-Smith, Charlotte Refdahl Thoudahl, Carol Fioresi, Wei Liu, Andrew Shaw, Gijsbert Gerritse
  • Patent number: 8137944
    Abstract: Variant polypeptides derivable from a parent polypeptide having non-maltogenic exoamylase activity, in which the variant polypeptides comprise an amino acid mutation at one or more positions selected from the group consisting of: 121, 161, 223, 146, 157, 158, 198, 229, 303, 306, 309, 316, 353, 26, 70, 145, 188, 272, 339, with reference to the position numbering of a Pseudomonas saccharophila exoamylase sequence shown as SEQ ID NO: 1.
    Type: Grant
    Filed: July 7, 2005
    Date of Patent: March 20, 2012
    Assignee: Danisco A/S
    Inventors: Casper Tune Berg, Patrick M. F. Derkx, Carol Fioresi, Gijsbert Gerritse, Anja Hemmingen Kellet-Smith, Karsten Matthias Kragh, Wei Liu, Andrew Shaw, Bo Spange Sørensen, Charlotte Refdahl Thoudahl
  • Patent number: 8129511
    Abstract: This invention relates to nucleic acids encoding amylase polypeptides, the encoded polypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered exo-specificity and/or thermostability. Some embodiments of the invention relate to said polypeptides and nucleic acids and their uses as non-maltogenic exoamylases in producing food products.
    Type: Grant
    Filed: February 8, 2011
    Date of Patent: March 6, 2012
    Assignee: Danisco A/S
    Inventors: Karsten Matthias Kragh, Bo Spange Sørensen, Casper Tune Berg, Kirsten Bojsen, Patrick M. F. Derkx, Carol Fioresi, Anja H. Kellett-Smith, Charlotte Refdahl Thoudahl, Oene R. Veltman, Gijsbert Gerritse, Wei Liu, Andrew Shaw
  • Publication number: 20110212241
    Abstract: This invention relates to nucleic acids encoding amylase polypeptides, the encoded polypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered exo-specificity and/or thermostability. Some embodiments of the invention relate to said polypeptides and nucleic acids and their uses as non-maltogenic exoamylases in producing food products.
    Type: Application
    Filed: February 8, 2011
    Publication date: September 1, 2011
    Inventors: Karsten Matthias Kragh, Bo Spange Sørensen, Casper Tune Berg, Kirsten Bojsen, Patrick M.F. Derkx, Carol Fioresi, Anja H. Kellett-Smith, Charlotte Refdahl Thoudahl, Oene R. Veltman, Gijsbert Gerritse, Wei Liu, Andrew Shaw
  • Patent number: 7833770
    Abstract: This is invention relates to amylase polypeptides, and nucleic acids encoding the polypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered thermostability.
    Type: Grant
    Filed: September 27, 2006
    Date of Patent: November 16, 2010
    Assignee: Danisco A/S
    Inventors: Karsten Matthias Kragh, Casper Tune Berg, Patrick M. F. Derkx, Anja H. Kellett-Smith, Charlotte Refdahl Thoudahl, Oene R. Veltman, Carol Fioresi, Gijsbert Gerritse, Wei Liu, Andrew Shaw
  • Patent number: 7776576
    Abstract: This invention relates to amylase polypeptides, and nucleic acids encoding the polpypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered thermostability.
    Type: Grant
    Filed: July 7, 2004
    Date of Patent: August 17, 2010
    Assignee: Danisco A/S
    Inventors: Karsten Matthias Kragh, Casper Tune Berg, Patrick M. F. Derkx, Anja H. Kellett-Smith, Charlotte Refdahl Thoudahl, Oene R. Veltman, Carol Fioresi, Wei Liu, Andrew Shaw, Gijsbert Gerritse
  • Publication number: 20090214706
    Abstract: We describe a PS4 variant polypeptide derivable from a parent polypeptide having non-maltogenic exoamylase activity, in which the PS4 variant polypeptide comprises an amino acid mutation at one or more positions selected from the group consisting of: 121, 161, 223, 146, 157, 158, 198, 229, 303, 306, 309, 316, 353, 26, 70, 145, 188, 272, 339, with reference to the position numbering of a Pseudomonas saccharophilia exoamylase sequence shown as SEQ ID NO: 1.
    Type: Application
    Filed: July 7, 2005
    Publication date: August 27, 2009
    Inventors: Casper Tune Berg, Patrick M.F. Derkx, Carol Fioresi, Gijsbert Gerritse, Anja Hemmingen Kellet-Smith, Karsten Matthias Kragh, Wei Liu, Andrew Shaw, Bo Spange Sørensen, Charlotte Refdahl Thoudahl
  • Publication number: 20080274531
    Abstract: This invention relates to amylase polypeptides, and nucleic acids encoding the polypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically the amylases of the current invention show an altered exospecifity.
    Type: Application
    Filed: February 1, 2008
    Publication date: November 6, 2008
    Inventors: Casper Tune Berg, Kirsten Bojsen, Patrick M.F. Derkx, Carol Fioresi, Gijsbert Gerritse, Karsten Matthias Kragh, Wei Liu, Andrew Shaw, Charlotte Refdahl Thoudahl, Anja Hemmingsen Kellett-Smith
  • Patent number: 6638737
    Abstract: The present invention provides a method for producing a secretable polypeptide in a host cell. In the method, a peptidyl prolyl cis-trans isomerase is overexpressed in a host cell, thereby increasing the yield of the secreted polypeptide.
    Type: Grant
    Filed: August 1, 2001
    Date of Patent: October 28, 2003
    Assignee: Danisco A/S
    Inventors: Patrick M. F. Derkx, Susan M. Madrid
  • Patent number: 6607904
    Abstract: The present invention provides a method for producing a secretable polypeptide in a host cell. In the method, a peptidyl prolyl cis-trans isomerase is overexpressed in a host cell, thereby increasing the yield of the secreted polypeptide.
    Type: Grant
    Filed: January 14, 2002
    Date of Patent: August 19, 2003
    Assignee: Danisco A/S
    Inventors: Patrick M. F. Derkx, Susan M. Madrid
  • Publication number: 20020150969
    Abstract: The present invention provides a method for producing a secretable polypeptide in a host cell, comprising overexpressing a peptidyl proly cis-trans isomerase in the host cell, thereby increasing the yield of the secreted polypeptide, and a novel peptidyl proly cis-trans isomerase from A. niger useful in such a method.
    Type: Application
    Filed: January 14, 2002
    Publication date: October 17, 2002
    Applicant: Danisco A/S
    Inventors: Patrick M.F. Derkx, Susan M. Madrid