Patents by Inventor Patrick Mailliet

Patrick Mailliet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemical derivatives as antitelomerase agents which bind specifically to the G-quadruplex DNA structures and their application as a specific anticancer agent
    Publication number: 20070232572
    Abstract: The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which is quite specific. It also relates to novel chemical compounds and their therapeutic application in humans.
    Type: Application
    Filed: February 6, 2004
    Publication date: October 4, 2007
    Applicants: Aventis Pharma S.A., Centre National De La Recherche Scientifique, Museum National D'Histoire Naturelle, Institut Curie, Commissariat A L'Energie Atomique, Universite De Reims Champagne-Ardenne
    Inventors: Augustin Hittinger, Thomas Caulfield, Patrick Mailliet, Herve Bouchard, Eliane Mandine, Jean-Louis Mergny, Lionel Guittat, Jean-Francois Riou, Dennis Gomez, Chafke Belmokhtar
  • Chemical derivatives and their application as antitelomerase agents
    Patent number: 7179816
    Abstract: The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which inhibits telomerase. It also relates to novel chemical compounds as well as their therapeutic application in humans.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: February 20, 2007
    Assignee: Aventis Pharma S.A.
    Inventors: Patrick Mailliet, Jean-Francois Riou, Marcel Alasia, Thomas Caulfield, Gilles Doerflinger, Jean-Louis Mergny, Abdelazize Laoui, Odile Petitgenet, Emmanuelle Renou
  • Indazole or indole derivatives, and use thereof in human medicine and more particularly in oncology
    Patent number: 7119115
    Abstract: The present invention relates to novel compounds derived from indazoles or indoles of formula (1) or formula (2), to methods for treating tumors or cancerous cells with compounds of formula (1) or formula (2) and to pharmacaetutical compositions comprising a pharmaceutically acceptable carrier and a compound of formula (1) or formula (2)
    Type: Grant
    Filed: January 21, 2004
    Date of Patent: October 10, 2006
    Assignee: Aventis Pharma S.A.
    Inventors: Michel Tabart, Eric Bacqué, Sylvie Wentzler, Cécile Combeau, Conception Nemecek, Patrick Mailliet, Fabienne Thompson
  • Substituted tetrahydro-1H-pyrazolo [3,4-c] pyridines, compositions comprising them, and use
    Patent number: 7109340
    Abstract: Substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines, compositions comprising them and use. The present invention relates in particular to novel substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines having therapeutic activity, which can be used in particular in oncology.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: September 19, 2006
    Assignee: Aventis Pharma S.A.
    Inventors: Fabienne Thompson, Patrick Mailliet, Teresa Damiano, Marie-Pierre Cherrier, Francois Clerc, Frank Halley, Hervé Bouchard, Laurence Gauzy-Lazo, Bernard Baudoin, Catherine Souaille, Fabrice Viviani, Michel Tabart
  • SUBSTITUTED TETRAHYDRO-1H-PYRAZOLO [3,4-C]PYRIDINES COMPOSITIONS COMPRISING THEM, AND USE
    Publication number: 20060199837
    Abstract: Substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines, compositions comprising them and use. The present invention relates in particular to novel substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines having therapeutic activity, which can be used in particular in oncology.
    Type: Application
    Filed: May 23, 2006
    Publication date: September 7, 2006
    Applicant: AVENTIS PHARMA S.A.
    Inventors: Fabienne Thompson, Patrick Mailliet, Teresa Damiano, Marie-Pierre Cherrier, Francois Clerc, Frank Halley, Herve Bouchard, Laurence Gauzy-Lazo, Bernard Baudoin, Catherine Squaille, Fabrice Viviani, Michel Tabart
  • 1,3-Diarylprop-2-en-1-ones, compositions containing them and use thereof
    Publication number: 20050203170
    Abstract: 1,3-Diarylprop-2-en-1-ones and derivatives, compositions containing them, manufacturing process and use. Substituted 1,3-diarylprop-2-en-1-ones with therapeutic activity may be used in oncology.
    Type: Application
    Filed: April 19, 2005
    Publication date: September 15, 2005
    Inventors: Patrick Mailliet, Cecile Combeau, Marie-Christine Bissery, Marie-Pierre Cherrier, Thomas Caulfield, Gilles Tiraboschi
  • Compounds derived from oxindoles and their therapeutic application in cancer treatment
    Patent number: 6930124
    Abstract: The invention relates to compounds of formula (I) in which R5 is chosen from the group consisting of: in which R2 is a C1-C3 alkyl group in which X may be Cl, Br, or F in which n is between 1 and 3, in the E or Z form, or a mixture of the two isomeric forms, possessing antimitotic, antiproliferative and antivascular properties through inhibition of the polymerization of tubulin into microtubules
    Type: Grant
    Filed: September 10, 2003
    Date of Patent: August 16, 2005
    Assignee: Aventis Pharma S. A.
    Inventors: Cécile Combeau, Patrick Mailliet, Marielle Chiron
  • Novel organophosphorus derivatives of indazoles and use thereof as medicinal products
    Publication number: 20050137171
    Abstract: The present invention relates in particular to novel chemical compounds, particularly to novel organophosphorus derivatives of indazoles, to the compositions containing them, and to the use thereof as medicinal products for treating cancers.
    Type: Application
    Filed: December 17, 2004
    Publication date: June 23, 2005
    Applicant: Aventis Pharma S.A.
    Inventors: Marie-Pierre Cherrier, Francois Clerc, Alain Commercon, Patrick Mailliet, Herve Minoux, Bruno Filoche-Romme
  • N-arylheteroaromatic products compositions containing them and use thereof
    Publication number: 20050130989
    Abstract: N-Arylheteroaromatic products, compositions containing them and use thereof. The present invention relates to novel chemical compounds, particularly to novel N-arylheteroaromatic products, to compositions containing them and to their use as medicinal products, in particular in oncology.
    Type: Application
    Filed: January 26, 2004
    Publication date: June 16, 2005
    Applicant: Aventis Pharma S. A.
    Inventors: Alain Le-Brun, Fabienne Thompson, Gilles Tiraboschi, Joseph Salvino, Patrick Mailliet
  • Substituted tetrahydro-1H-pyrazolo [3,4-c] pyridines, compositions comprising them, and use
    Publication number: 20050096345
    Abstract: Substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines, compositions comprising them and use. The present invention relates in particular to novel substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines having therapeutic activity, which can be used in particular in oncology.
    Type: Application
    Filed: July 9, 2004
    Publication date: May 5, 2005
    Applicant: Aventis Pharma S.A.
    Inventors: Fabienne Thompson, Patrick Mailliet, Teresa Damiano, Marie-Pierre Cherrier, Francois Clerc, Frank Halley, Herve Bouchard, Laurence Gauzy-Lazo, Bernard Baudoin, Catherine Souaille, Fabrice Viviani, Michel Tabart
  • Triazine derivatives and their application as antitelomerase agents
    Patent number: 6887873
    Abstract: The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which is quite specific. It also relates to novel chemical compounds as well as their therapeutic application in humans.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: May 3, 2005
    Assignee: Aventis Pharma S.A.
    Inventors: Patrick Mailliet, Abdelazize Laoui, Jean-François Riou, Gilles Doerflinger, Jean-Louis Mergny, François Hamy, Thomas Caulfield
  • Substituted arylcycloalkanes, compositions containing them and use thereof
    Patent number: 6887904
    Abstract: Substituted arylcycloalkanes, compositions containing them and use thereof. The present invention relates especially to substituted arylcycloalkanes with therapeutic activity, which may be used such as in oncology.
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: May 3, 2005
    Assignee: Aventis Pharma S. A.
    Inventors: Patrick Mailliet, Marc Capet, Gilles Tiraboschi, Thomas Caulfield
  • Chemical derivatives and their application as antitelomerase agents
    Publication number: 20050070571
    Abstract: The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which is quite specific. It also relates to novel chemical compounds as well as their therapeutic application in humans.
    Type: Application
    Filed: November 19, 2004
    Publication date: March 31, 2005
    Applicant: Aventis Pharma S.A.
    Inventors: Patrick Mailliet, Abdekazize Laoui, Jean-Francois Riou, Gilles Doerflinger, Jean-Louis Mergny, Francois Hamy, Thomas Caulfield
  • Chemical derivatives and their application as antitelomerase agents
    Publication number: 20050070575
    Abstract: The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which inhibits telomerase. It also relates to novel chemical compounds as well as their therapeutic application in humans.
    Type: Application
    Filed: September 30, 2004
    Publication date: March 31, 2005
    Applicant: Aventis Pharma S.A.
    Inventors: Patrick Mailliet, Jean-Francois Riou, Marcel Alasia, Thomas Caulfield, Gilles Doerflinger, Jean-Louis Mergny, Abdelazize Laoui, Odile Petitgenet, Emmanuelle Renou
  • Chemical derivatives and their application as antitelomerase agents
    Patent number: 6858608
    Abstract: The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which inhibits telomerase. It also relates to novel chemical compounds as well as their therapeutic application in humans.
    Type: Grant
    Filed: January 9, 2002
    Date of Patent: February 22, 2005
    Assignee: Aventis Pharma S.A.
    Inventors: Patrick Mailliet, Jean-François Riou, Marcel Alasia, Thomas Caulfield, Gilles Doerflinger, Jean-Louis Mergny, Abdelazize Laoui, Odile Petitgenet, Emmanuelle Renou
  • Aryl-heteroaromatic compounds, compositions comprising them and use
    Publication number: 20050020593
    Abstract: A series of aryl-heteroaromatic compounds, compositions comprising them and use thereof are disclosed and claimed. The present invention relates in particular to novel aryl-heteroaromatic compounds exhibiting anticancer activity, and in particular inhibitory activity with regard to tubulin polymerization.
    Type: Application
    Filed: July 23, 2004
    Publication date: January 27, 2005
    Applicant: Aventis Pharma
    Inventors: Patrick Mailliet, Alain Le-Brun, Fabienne Thompson, Gilles Tiraboschi
  • Aryl-heteroaromatic products, compositions comprising them and use
    Publication number: 20050014765
    Abstract: Aryl-heteroaromatic products, compositions comprising them and use. The present invention relates to novel chemical compounds, particularly to novel aryl-heteroaromatic products, to compositions comprising them, and to their use as medicaments, in particular in oncology.
    Type: Application
    Filed: June 3, 2004
    Publication date: January 20, 2005
    Applicant: Aventis Pharma S.A.
    Inventors: Patrick Mailliet, Alain Le Brun, Fabienne Thompson, Gilles Tiraboschi
  • 1-Aryl-3-(indol-5-yl) prop-2-en-1-ones, compositions containing them and use
    Publication number: 20040229931
    Abstract: 1-Aryl-3-(indol-5-yl)prop-2-en-1-ones, compositions containing them and use thereof are disclosed and claimed. The present invention relates specifically to novel substituted 1-aryl-3-(indol-5-yl)prop-2-en-1-ones of formula (I) having a therapeutic activity, particularly, in oncology.
    Type: Application
    Filed: April 30, 2004
    Publication date: November 18, 2004
    Applicant: Aventis Pharma S. A.
    Inventors: Patrick Mailliet, Fabienne Thompson, Luc Bertin, Gerard Leclere, Gilles Tiraboschi
  • Indazole or indole derivatives, and use thereof in human medicine and more particularly in oncology
    Publication number: 20040162276
    Abstract: The present invention relates to novel compounds derived from indazoles or indoles of formula (1) or formula (2), to methods for treating tumors or cancerous cells with compounds of formula (1) or formula (2) and to pharmacaetutical compositions comprising a pharmaceutically acceptable carrier and a compound of formula (1) or formula (2).
    Type: Application
    Filed: January 21, 2004
    Publication date: August 19, 2004
    Applicant: Aventis Pharma S.A.
    Inventors: Michel Tabart, Eric Bacque, Sylvie Wentzler, Cecile Combeau, Conception Nemecek, Patrick Mailliet, Fabienne Thompson
  • 1,3-DIARYLPROP-2-EN-1-ONES, COMPOSITIONS CONTAINING THEM AND USE THEREOF
    Publication number: 20040147584
    Abstract: 1,3-Diarylprop-2-en-1-ones and derivatives, compositions containing them, manufacturing process and use. Substituted 1,3-diarylprop-2-en-1-ones with therapeutic activity may be used in oncology.
    Type: Application
    Filed: December 4, 2002
    Publication date: July 29, 2004
    Applicant: Aventis Pharma S.A.
    Inventors: Patrick Mailliet, Cecile Combeau, Marie-Christine Bissery, Mari-Pierre Cherrier, Thomas Caulfield, Gilles Tiraboschi