Abstract: A method for producing a base body of a valve housing for a hydraulic control valve includes machining a front-side section of a control edge into an unmachined base body for the base body with a cutting process in a front-side machining step. In the cutting process, a cutting tool is guided from a coupling side through a machining valve pocket to the front-side section of the control edge.

Abstract: A method for producing a base body of a valve housing for a hydraulic control valve includes machining a front-side section of a control edge into an unmachined base body for the base body with a cutting process in a front-side machining step. In the cutting process, a cutting tool is guided from a coupling side through a machining valve pocket to the front-side section of the control edge.

Abstract: A filter device has a filter element (1) received in a filter housing of at least two interconnectable housing parts (17, 19). The filter element (1) can be fixed to a housing part (19) in a removable manner by one screw connection (32, 33). An additional screw connection (17, 41) is provided for connecting the housing parts (17, 19). To transmit a torque between threaded elements (33) of the one screw connection (32, 33) and of the additional screw connection (41), the threaded elements are rotatable relative to each other. A coupling device (43, 46, 61) is added that allows an additional rotational movement of the threaded element (17) of the additional screw connection (41) when the threaded element (33) of the one screw connection (32, 33) reaches the fixed rotational state.

Abstract: The invention relates to a filter device with a filter element (1) which can be received in a filter housing that consists of at least two interconnectable housing parts (17, 19). The filter element (1) can be fixed to a housing part (19) in a removable manner by means of a screw connection (32, 33), and an additional screw connection (17, 41) is provided for connecting the housing parts (17, 19). The invention is characterized in that in order to transmit a torque between threaded elements (33) of the screw connection (32, 33) and of the additional screw connection (41), said threaded elements being rotatable relative to each other, a coupling device (43, 46, 61) is added which allows an additional rotational movement of the threaded element (17) of the additional screw connection (41) when the threaded element (33) of the screw connection (32, 33) reaches the fixed rotational state.

Abstract: The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses.

Abstract: The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses.

Abstract: The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses.

Abstract: The invention relates to the finding that virus like particles (VLPs) can be loaded with immunostimulatory substances, in particular with DNA oligonucleotides containing non-methylated C and G (CpGs). Such CpG-VLPs are dramatically more immunogenic than their CpG-free counterparts and induce enhanced B and T cell responses. The immune response against antigens optionally coupled, fused or attached otherwise to the VLPs is similarly enhanced as the immune response against the VLP itself. In addition, the T cell responses against both the VLPs and antigens are especially directed to the Th1 type. Antigens attached to CpG-loaded VLPs may therefore be ideal vaccines for prophylactic or therapeutic vaccination against allergies, tumors and other self-molecules and chronic viral diseases.

Abstract: The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses.

Abstract: The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses.

Abstract: The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses.

Abstract: A filtering apparatus includes a pot-type filter housing (10), a filter element (28) accommodated in the housing, a holding mechanism (38) disposed in the filter housing (10) to removably fix the filter element along its longitudinal axis, and a sealing device (60) that seals between a lid (20) of the filter housing (10) and the filter element (28). The holding mechanism (38) is provided with cooperating holding elements embodied on the interior face of the filter housing (10) as well as on the filter element (28). The filtering apparatus dispenses with the need for O-seals that are known in prior art and extend in a radial direction between the filter element and the filter head as a housing lid because the sealing device (60) encompasses at least one sealing edge (62) or sealing surface placed parallel to the longitudinal axis in a radial direction and seals under the effect of the pressure applied it by the holding mechanism (38).

Abstract: The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses.

Abstract: The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses.

Abstract: The invention relates to a filtering apparatus comprising a pot-type filter housing (10), a filter element (28) that is accommodated therein, a holding mechanism (38) which is disposed in the filter housing (10) in order to removably fix the filter element along the longitudinal axis thereof, and a sealing device (60) that seals between a lid (20) of the filter housing (10) and the filter element (28). The holding mechanism (38) is provided with cooperating holding elements which are embodied on the interior face of the filter housing (10) as well as on the filter element (28).

Abstract: In a cable television system a system for supporting SCU return in FTTB-MDU and FTTC/FTTcab configurations. Fiber, baseband transceiver and networking capabilities are shared with data and voice portions of the system for enabling communication from the SCUs to the HE over a packet based networking system. Return packets/upstream packets are passed into the network upstream channel only when a signal is present for eliminating transmission of upstream traffic that contains no signal for conserving upstream bandwidth.

Abstract: The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses.

Abstract: A service convergence fabric (103) is operably disposed between a plurality of independent access networks, control networks, and service networks (104) and a converged application layer (100). This service convergence fabric is then used (202) to receive a service request, process the service request, provide a corresponding response, and publish that response to facilitate the service request. Processing the service request can comprise processing the service request with respect to resources to support the service request, user session status as corresponds to the service request, and user preferences as correspond to the service request. Providing a response can comprise providing a response that comprises at least one of a processed service request and a converged response to the service request.

Abstract: The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses.

Abstract: A filtering apparatus includes a pot-type filter housing (10), a filter element (28) accommodated in the housing, a holding mechanism (38) disposed in the filter housing (10) to removably fix the filter element along its longitudinal axis, and a sealing device (60) that seals between a lid (20) of the filter housing (10) and the filter element (28). The holding mechanism (38) is provided with cooperating holding elements embodied on the interior face of the filter housing (10) as well as on the filter element (28). The filtering apparatus dispenses with the need for O-seals that are known in prior art and extend in a radial direction between the filter element and the filter head as a housing lid because the sealing device (60) encompasses at least one sealing edge (62) or sealing surface placed parallel to the longitudinal axis in a radial direction and seals under the effect of the pressure applied it by the holding mechanism (38).