Abstract: A motor vehicle door latch, in particular a tailgate latch, which is equipped with a locking mechanism comprising a catch and a pawl. Furthermore, a triggering element working on the pawl is provided for which is set up at least to lift the pawl. Furthermore, a memory element, which at least guarantees an unimpeded opening movement of the catch when the pawl is lifted. The memory element maintains the pawl in its elevated position.

Abstract: A motor vehicle door latch, in particular a tailgate latch, which is equipped with a locking mechanism comprising a catch and a pawl. Furthermore, a triggering element working on the pawl is provided for which is set up at least to lift the pawl. Furthermore, a memory element, which at least guarantees an unimpeded opening movement of the catch when the pawl is lifted. The memory element maintains the pawl in its elevated position.

Abstract: A photosensor control unit for use in a lighting module has a light sensor and a switch adapted to operably control a light source such as a plurality of LEDs responsive to the light sensor. The light source is adapted to be mounted in the lighting module, and is configured to produce light having wavelengths within a first range of wavelengths. The light sensor is adapted to be mounted on or about the lighting module, and is responsive to light having wavelengths within a second range of wavelengths. The second range of wavelengths is exclusive of the first range of wavelengths. The switch is adapted to operably control the light source responsive to the light sensor such that the light source emits light having wavelengths within the first range of wavelengths responsive to the presence or absence of light within the second range of wavelengths.

Abstract: A treatment process is disclosed that comprises administering an effective amount of an aromatic sulfone hydroxamic acid that exhibits excellent inhibitory activity of one or more matrix metalloprotease (MMP) enzymes, such as MMP-2, MMP-9, and MMP-13, while exhibiting substantially less inhibition at least of MMP-1 to a host having a condition associated with pathological matrix metalloprotease activity. The administered enzyme inhibitor corresponds in structure to formula (I), below, or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are both hydrido or R1 and R2 together with the atoms to which they are bonded form a 5- to 8-membered ring containing one, two, or three heteroatoms in the ring that are oxygen, sulfur, or nitrogen. R3 in formula (I) is an optionally substituted aryl or optionally substituted heteroaryl radical.

Abstract: This invention is directed generally to proteinase (also known as “protease”) inhibitors, and, more particularly, to piperidinyl- and piperazinyl-sulfonylmethyl hydroxamic acids that, inter alia, inhibit matrix metalloproteinase (also known as “matrix metalloprotease” or “MMP”) activity and/or aggrecanase activity. Such hydroxamic acids generally correspond in structure to the following formula: (wherein A1, A2, Y, E1, E2, E3, and Rx are as defined in this specification), and further include salts of such compounds. This invention also is directed to compositions of such hydroxamic acids, intermediates for the syntheses of such hydroxamic acids, methods for making such hydroxamic acids, and methods for treating conditions (particularly pathological conditions) associated with MMP activity and/or aggrecanase activity.

Abstract: This invention is directed generally to proteinase (also known as “protease”) inhibitors, and, more particularly, to piperidinyl- and piperazinyl-sulfonylmethyl hydroxamic acids that, inter alia, inhibit matrix metalloproteinase (also known as “matrix metalloprotease” or “MMP”) activity and/or aggrecanase activity. Such hydroxamic acids generally correspond in structure to the following formula: (wherein A1, A2, Y, E1, E2, E3, and Rx are as defined in this specification), and further include salts of such compounds. This invention also is directed to compositions of such hydroxamic acids, intermediates for the syntheses of such hydroxamic acids, methods for making such hydroxamic acids, and methods for treating conditions (particularly pathological conditions) associated with MMP activity and/or aggrecanase activity.

Abstract: A photosensor control unit for use in a lighting module has a plurality of LEDs, a light sensor, and a switch adapted to operably control the plurality of LEDs responsive to the light sensor. The plurality of LEDs are adapted to be mounted in the lighting module, and are configured to produce light having wavelengths within a first range of wavelengths. The light sensor is adapted to be mounted in the lighting module adjacent the plurality of LEDs, and is responsive to light having wavelengths within a second range of wavelengths. The second range of wavelengths is exclusive of the first range of wavelengths. The switch is adapted to operably control the plurality of LEDs responsive to the light sensor such that the plurality of LEDs emit light having wavelengths within the first range of wavelengths responsive to the presence or absence of light within the second range of wavelengths.

Abstract: A disclosed substrate includes an electrically insulating circuit board, a pair of electrical lead pads adapted for mounting a light-emitting diode (LED) on a first surface, and a heat dissipating structure on the first surface. The heat dissipating structure includes an LED thermal pad adapted to abut the LED when mounted on the electrical lead pads, and a heat dissipation region extending from, and thermally coupled to, the LED thermal pad. The substrate also includes a thermally conductive plating on a second surface of the substrate opposite the heat dissipation region. A described lighting assembly includes the substrate, multiple LEDs connected to the electrical lead pads of the substrate, and multiple traces of the substrate connect the LEDs in a series circuit electrically isolated from the heat dissipating structures.

Abstract: Relay switching circuits for supplying power to a vehicle exterior lighting system to provide for daytime running lights and which are controlled by solid state logic circuits, depending upon the condition of either or both of the vehicle starter and ignition switches.

Abstract: An automated daytime running light system for surface transport vehicles having headlights and taillights which includes a daytime running light control circuit which activates the highbeam filament of the headlights at a reduced power level whenever the vehicle ignition is ON and the starter motor OFF during daylight conditions. In one embodiment, the daytime running light control circuit activates the high beam filaments of the headlight at a reduced power level and also activates the parking lights to provide taillights whenever the vehicle ignition is ON and the starter motor OFF during daylight conditions.