Abstract: The present invention broadly relates to a process for preparing fatty acid alkyl esters from fat-containing feedstocks using sulfonated fatty acid catalysts.

Abstract: The present invention broadly relates to a process for preparing fatty acid alkyl esters from fat-containing feedstocks using sulfonated fatty acid catalysts.

Abstract: The present invention broadly relates to a process for preparing fatty acid alkyl esters from fat-containing feedstocks using sulfonated fatty acid catalysts.

Abstract: The present invention relates generally to a method of modulating T cell functional activity by utilising ?-amino acid substituted peptides and to agents useful for the same. More particularly, the present invention relates to a method of modulating class I restricted T cell activity by utilising ?-amino acid substituted peptides and to agents useful for the same. The method of the present invention is useful, inter alia, in the treatment and/or prophylaxis of conditions characterised by suboptimal T cell stimulation such as that which occurs in some viral infections and in anti-tumour immunity, as well as aberrant, unwanted or otherwise inappropriate T cell functioning such as, but not limited to, graft rejection or autoimmune conditions, the present invention is further directed to methods of identifying, designing and/or modifying agents capable of modulating T cell functional activity.

Abstract: The present application is directed to a method of synthesis of a bicyclic or polycyclic compound of formula I or formula II: in which E, G, Y, n, m, R, R1, R2, R3, R6, R7, R8 and R9 are as defined.

Abstract: The present invention relates to methods of processing of chemical samples containing compounds or molecular complexes using a binding material comprising a method of separating a compound or molecular complex on the basis of the ability of the compound or molecular complex to associate with a binding material, from compounds or molecular complexes having different association characteristics, said method comprising: (a) bringing a sample containing said compound or molecular complex into contact with a binding material, the binding material comprising: (i) a support, (ii) at least one terminal moiety selected from the group consisting of lecithins, lysolecithins, cephalins, sphingomyelin, cardiolipin, glycolipids, gangliosides, cerebrosides and phospholipids, and (iii) at least one linker of the formula (I) wherein R1 and R2 may be the same or different and are independently selected from the group consisting of: H, OH, C1-C6 alkyl, C2-C6 alkenyl, halogen, C1-C6 alkoxy, C2-C6 alkenyloxy and aryloxy, or

Abstract: A method of synthesis of a bicyclic or polycyclic compound of formula (I) or formula (II) in which: E represents an electrophile; each of R, R1, R2, R3, R6, R7, R8, R9 and X independently represents the common organic substituent groups defined in claim 1; Y represents C(r12)R13, O, NR14, or S; Z represents O, NR15, S or CR16W; G represents W or X; W represents an electron withdrawing group; X has the same definition as R, and W═W; and each of n and m represents an integer from 0 to 100. The method comprises the steps of (a) activating a compound of formula (III); 8b) subjecting a compound of formula (IV) to nucleophilic addition with the activated form of compound III; (c) subjecting the product of step (b) to ring closing metathesis; and (d) subjecting the product of step (c) to stereoselective ring closure. The methods of invention are useful in the synthesis of candidate pharmaceutical agents or intermediates in drugs synthesis.