Patents by Inventor Patrick Pfister

Patrick Pfister has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10913787
    Abstract: Provided herein are polypeptides that bind to Musk compounds. Also provided are nucleic acid sequences that encode for the polypeptides. Further provided herein is a method for identifying a compound that activates, mimics, blocks, inhibits, modulates, and/or enhances the activity of an olfactory receptor that is activated by a polycyclic Musk or a nitro Musk wherein the receptor is a polypeptide having an amino acid sequence that is at least 75% identical to Olfr96 or OR11A1, wherein the method includes a) contacting the receptor, or a chimera or fragment thereof with a compound and b) determining whether the compound has an effect on the activity of the receptor.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: February 9, 2021
    Assignee: Firmenich SA
    Inventors: Patrick Pfister, Matthew Rogers
  • Publication number: 20210003553
    Abstract: The present disclosure relates to a method for identifying a compound that binds, suppresses, blocks, inhibits, and/or modulates the activity of an olfactory receptor that is activated by a laundry malodor causing substance, a moldy malodour causing substance and/or a sweat malodor-causing substance. The method includes contacting a test substance and the laundry malodor and/or sweat malodor-causing substance to an olfactory receptor polypeptide.
    Type: Application
    Filed: November 21, 2018
    Publication date: January 7, 2021
    Inventors: Huey-Ling KAO, Mushhood SHEIKH, Patrick PFISTER, Cristinel SANDU, Barry EVANS, Nicholas O'LEARY, Ben SMITH
  • Publication number: 20200408738
    Abstract: The various aspects presented herein relate to the perfumery industry. More particularly, the various aspects presented herein relate to assays and methods for screening and identifying compositions and/or ingredients that intensify a subject's perception of target odorant compounds based on the use of particular olfactory receptors activated by the target odorant compound.
    Type: Application
    Filed: December 20, 2018
    Publication date: December 31, 2020
    Inventors: Patrick PFISTER, Matthew ROGERS, Lily WU, Christian MARGOT
  • Publication number: 20200385648
    Abstract: The various aspects presented herein relate to the perfumery industry. More particularly, the various aspects presented herein relate to compositions and/or ingredients that increase a subjects perception of musk compounds, methods for intensifying a subjects perception of musk compounds, as well as to the perfumed articles or perfuming compositions comprising as an active ingredient, a compound of Formula (I).
    Type: Application
    Filed: December 20, 2018
    Publication date: December 10, 2020
    Applicant: Firmenich, SA
    Inventors: Patrick PFISTER, Matthew ROGERS, Jana PIKA, Florian DE NANTEUIL, Nicholas O'LEARY, Christie DELAURA
  • Publication number: 20200345601
    Abstract: The various aspects presented herein relate to the perfumery industry. More particularly, the various aspects presented herein relate to the use of volatile compositions to limit, decrease or eliminate the perception of malodor. Such compositions include at least one malodor antagonist optionally combined with perfuming ingredients. Such compositions, their use in combination with delivery systems and their applications in consumer products are also objects of the present disclosure.
    Type: Application
    Filed: November 21, 2018
    Publication date: November 5, 2020
    Applicant: Firmenich SA
    Inventors: Huey-Ling KAO, Stefan Alexander RUIDER, Ben SMITH, Gary MARR, Matthew ROGERS, Mushhood SHEIKH, Anna WU, Patrick PFISTER, Anthony Alexander BIRKBECK, Julien COULOMB
  • Publication number: 20200048326
    Abstract: Provided herein are polypeptides that bind to Musk compounds. Also provided are nucleic acid sequences that encode for the polypeptides. Further provided herein is a method for identifying a compound that activates, mimics, blocks, inhibits, modulates, and/or enhances the activity of an olfactory receptor that is activated by a polycyclic Musk or a nitro Musk wherein the receptor is a polypeptide having an amino acid sequence that is at least 75% identical to Olfr96 or OR11A1, wherein the method includes a) contacting the receptor, or a chimera or fragment thereof with a compound and b) determining whether the compound has an effect on the activity of the receptor.
    Type: Application
    Filed: June 9, 2016
    Publication date: February 13, 2020
    Applicant: Firmenich SA
    Inventors: Patrick PFISTER, Matthew ROGERS
  • Publication number: 20200002399
    Abstract: Provided herein are polypeptides that bind to the malodour-causing substance DMTS. Also provided are nucleic acid N sequences that encode for the polypeptides. Further provided herein is a method for identifying a compound that binds, suppresses, blocks, inhibits, and/or modulates the activity of one or more olfactory receptor that is activated by the malodor-causing substance DMTS comprising a) contacting the receptor, or a chimera or fragment thereof with a compound and b) determining whether the compound has an effect on the activity of the receptor. Further provided is an expression vector comprising the nucleic acid encoding the polypeptides described as well as a non-human organism or a host cell modified to express a receptor that is activated by DMTS. Also provided is the use of the polypeptides for identifying malodor modulating compounds.
    Type: Application
    Filed: March 8, 2018
    Publication date: January 2, 2020
    Inventors: Patrick Pfister, Matthew Rogers, Huey-Ling Kao, Claude Ayome Abibi
  • Publication number: 20180298069
    Abstract: Provided herein is a cell line with improved odorant receptor function comprising an activated endogenous RTP1 gene, which further expresses an RTP1 protein. Further provided herein is a method for specifically activating an endogenous RTP1 gene in a eukaryotic cell using a CRISPR/Cas9 derived technique. Also provided herein is a method for identifying compounds with desired effects such as perfume or aroma modulators in said cell line.
    Type: Application
    Filed: June 9, 2016
    Publication date: October 18, 2018
    Applicant: Firmenich SA
    Inventors: Hyo-Young JEONG, Patrick PFISTER, Matthew ROGERS
  • Publication number: 20180208637
    Abstract: Provided here are new methods to identify specific families of mammalian odorant receptors for odorants or aroma, particularly indole and skatole malodors and their use in assays that may be used to discover compounds that modulate (blocking, enhancing, masking or mimicking compounds) their activity. Orphan mouse odorant receptors are identified from olfactory sensory neurons that respond to target compounds. The resulting receptors as well as their human counterparts can be screened in assays against test compounds to confirm their identity as odorant or aroma receptors, particularly malodor receptors and subsequently discover for example modulators that inhibit the perception of the malodor in humans.
    Type: Application
    Filed: January 22, 2018
    Publication date: July 26, 2018
    Applicant: Firmenich SA
    Inventors: Patrick PFISTER, Matthew ROGERS, Khalid Jerod PARRIS
  • Patent number: 9914760
    Abstract: Provided here are new methods to identify specific families of mammalian odorant receptors for odorants or aroma, particularly indole and skatole malodors and their use in assays that may be used to discover compounds that modulate (blocking, enhancing, masking or mimicking compounds) their activity. Orphan mouse odorant receptors are identified from olfactory sensory neurons that respond to target compounds. The resulting receptors as well as their human counterparts can be screened in assays against test compounds to confirm their identity as odorant or aroma receptors, particularly malodor receptors and subsequently discover for example modulators that inhibit the perception of the malodor in humans.
    Type: Grant
    Filed: June 28, 2014
    Date of Patent: March 13, 2018
    Assignee: Firmenich SA
    Inventors: Patrick Pfister, Matthew E. Rogers, Khalid Jerod Parris
  • Patent number: 8959798
    Abstract: A midsole element to be mounted to the lower surface of an insole of a shoe as a heel, wherein the midsole element has a upper surface adapted to be mounted on the lower surface of the insole and a lower surface, wherein the midsole element comprises a core and a resilient compression element being softer than the core. The midsole element allows a pivoting movement of the upper surface of the midsole element against the lower surface of the midsole element in, at least, an essentially transverse direction to the longitudinal axis of the midsole element in a mounted state, wherein the core has a form of a rounded cone or sphere within the resilient compression element. The midsole element can also be mounted to the lower surface of a shoe under the forefoot portion, wherein the core has the form of a round ridge.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: February 24, 2015
    Assignee: Zurinvest AG
    Inventor: Patrick Pfister
  • Publication number: 20150005177
    Abstract: Provided here are new methods to identify specific families of mammalian odorant receptors for odorants or aroma, particularly indole and skatole malodors and their use in assays that may be used to discover compounds that modulate (blocking, enhancing, masking or mimicking compounds) their activity. Orphan mouse odorant receptors are identified from olfactory sensory neurons that respond to target compounds. The resulting receptors as well as their human counterparts can be screened in assays against test compounds to confirm their identity as odorant or aroma receptors, particularly malodor receptors and subsequently discover for example modulators that inhibit the perception of the malodor in humans.
    Type: Application
    Filed: June 28, 2014
    Publication date: January 1, 2015
    Applicant: FIRMENICH SA
    Inventors: Patrick PFISTER, Matthew E. ROGERS, Khalid Jerod PARRIS
  • Publication number: 20120297641
    Abstract: A midsole element to be mounted to the lower surface of an insole of a shoe as a heel, wherein the midsole element has a upper surface adapted to be mounted on the lower surface of the insole and a lower surface, wherein the midsole element comprises a core and a resilient compression element being softer than the core. The midsole element allows a pivoting movement of the upper surface of the midsole element against the lower surface of the midsole element in, at least, an essentially transverse direction to the longitudinal axis of the midsole element in a mounted state, wherein the core has a form of a rounded cone or sphere within the resilient compression element. The midsole element can also be mounted to the lower surface of a shoe under the forefoot portion, wherein the core has the form of a round ridge.
    Type: Application
    Filed: June 22, 2012
    Publication date: November 29, 2012
    Applicant: Zurinvest AG
    Inventor: Patrick Pfister
  • Patent number: 8266825
    Abstract: A shoe having an outsole and an insole. The outsole has an upper surface in contact with the lower surface of the insole. The upper surface of the outsole has at least two depressions being complementary with embossments provided on the lower surface of the insole, allowing a pivoting movement of the front and/or back portion of the insole against the lower outsole surface of the shoe in, at least, an essentially transverse direction to the longitudinal axis of the shoe, when the foot wearing the shoe is pivoted against the ground. To support this movement the insole is more rigid than the outsole and is attached to the outsole.
    Type: Grant
    Filed: June 11, 2009
    Date of Patent: September 18, 2012
    Assignee: Zurinvest AG
    Inventor: Patrick Pfister
  • Publication number: 20090307925
    Abstract: A shoe comprises a sole and an insole. The sole comprises an upper surface being in contact with the lower surface of the insole. Said upper surface of the sole comprises at least two depressions being complementary with embossments provided on the lower surface of the insole, allowing a pivoting movement of the front and/or back portion of the insole against the lower outsole surface of the shoe in, at least, an essentially transverse direction to the longitudinal axis of the shoe, when the foot wearing the shoe is pivoted against ground. To support this movement the insole is more rigid than the outsole and is attached to the outsole.
    Type: Application
    Filed: June 11, 2009
    Publication date: December 17, 2009
    Applicant: ZURINVEST AG
    Inventor: Patrick Pfister