Patents by Inventor Patrick PILIE

Patrick PILIE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Replication stress response biomarkers for immunotherapy response
    Patent number: 11851712
    Abstract: Methods for increasing immune therapy response and predicting likelihood of cancer metastasis by analyzing the expression of genes associated with replication stress response. In some aspects, cancers are treated with immune checkpoint inhibitors and/or MEK inhibitors. Methods for selecting patients by analyzing the expression of genes associated with a defect in replication stress response are also provided.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: December 26, 2023
    Assignee: Board of Regents, The University of Texas System
    Inventors: Daniel McGrail, Shiaw-Yih Lin, Patrick Pilie, Eric Jonasch, Curtis Chun-Jen Lin
  • REPLICATION STRESS RESPONSE BIOMARKERS FOR IMMUNOTHERAPY RESPONSE
    Publication number: 20210130906
    Abstract: Methods for increasing immune therapy response and predicting likelihood of cancer metastasis by analyzing the expression of genes associated with replication stress response. In some aspects, cancers are treated with immune checkpoint inhibitors and/or MEK inhibitors. Methods for selecting patients by analyzing the expression of genes associated with a defect in replication stress response are also provided.
    Type: Application
    Filed: March 6, 2019
    Publication date: May 6, 2021
    Applicant: Board of Regents, The University of Texas System
    Inventors: Daniel McGRAIL, Shiaw-Yih LIN, Patrick PILIE, Eric JONASCH, Curtis Chun-Jen LIN