Patents by Inventor Patrick Powers

Patrick Powers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11633416
    Abstract: Oral formulations comprising a compound of Formula (I) and a chelating agent are provided, wherein compounds of Formula (I) have the structure: wherein, W, X, Y, Z, Ra, Rc, and each Rg are as defined herein. Also provided are methods of preparation, methods of use, and specific dosage forms.
    Type: Grant
    Filed: March 5, 2021
    Date of Patent: April 25, 2023
    Assignee: ARCUS BIOSCIENCES, INC.
    Inventors: Kenneth Victor Lawson, Manmohan Reddy Leleti, Jay Patrick Powers
  • Patent number: 11499663
    Abstract: A water main tapping device and method includes a saddle body including an arcuate portion between a first end and a second end, wherein the saddle body includes a saddle opening at a location between the first end and the second end, and a corporation stop body formed integrally with and extending from the saddle body. The corporation stop body includes a base with an inlet cavity in fluid communication with the saddle opening, a housing extending from the base and having a valve cavity in which a rotatable valve is positioned and which is in fluid communication with the inlet cavity, and a connector end extending from the housing and including an outlet in fluid communication with the valve cavity.
    Type: Grant
    Filed: September 30, 2021
    Date of Patent: November 15, 2022
    Assignee: PowerSeal Pipeline Products
    Inventor: Patrick Powers
  • Patent number: 11433189
    Abstract: An aerosol delivery system has a nebulizer and a humidifier providing a gas flow to the nebulizer. A controller varies humidity level of the gas flow to the nebulizer so that if the nebulizer is not operating it has about 100% humidity and it is operating the value is less to allow for the humidification effect of the nebulizer. The control may be achieved by dynamically varying proportions of flow through a dry branch and a humidification branch.
    Type: Grant
    Filed: April 20, 2020
    Date of Patent: September 6, 2022
    Assignee: Stamford Devices Limited
    Inventor: Patrick Power
  • Publication number: 20220273889
    Abstract: A nebuliser control device has a manually adjustable user interface and a cable extending from the interface to a power source, and a cable extending from the interface to an aerosol generator. The interface is manually adjustable by physical movement of an actuator such a slider or a rotating knob to locally control the operation of the aerosol generator.
    Type: Application
    Filed: July 29, 2020
    Publication date: September 1, 2022
    Applicant: STAMFORD DEVICES LIMITED
    Inventors: Patrick POWER, Michael CASEY, Anthony REDMOND
  • Publication number: 20220265940
    Abstract: A nebulizer device has an aerosol generator mounted in a housing, and a mouthpiece. The device is adapted for delivery of an active agent in an aerosol into the buccal cavity, with droplet size greater than 10 ?m. Aerosolization is started at or after the end of breath inhalation and is stopped at or before the start of breath inhalation. The flow is via mouthpiece with internal ridges which periodically narrow the flow path volume to so that droplets coalesce in the flow path before the mesh.
    Type: Application
    Filed: July 23, 2020
    Publication date: August 25, 2022
    Applicant: STAMFORD DEVICES LIMITED
    Inventors: Colin TELFER, Patrick Power
  • Patent number: 11407712
    Abstract: Compounds that inhibit HIF-2?, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by HIF-2?.
    Type: Grant
    Filed: March 18, 2021
    Date of Patent: August 9, 2022
    Assignee: ARCUS BIOSCIENCES, INC.
    Inventors: Joel Worley Beatty, Samuel Lawrie Drew, Matthew Epplin, Jeremy Thomas Andre Fournier, Balint Gal, Tezcan Guney, Karl T. Haelsig, Clayton Hardman, Steven Donald Jacob, Jenna Leigh Jeffrey, Jaroslaw Kalisiak, Kenneth Victor Lawson, Manmohan Reddy Leleti, Erick Allen Lindsey, Artur Karenovich Mailyan, Debashis Mandal, Guillaume Mata, Hyunyoung Moon, Jay Patrick Powers, Brandon Reid Rosen, Yongli Su, Anh Thu Tran, Zhang Wang, Xuelei Yan, Kai Yu
  • Publication number: 20220081665
    Abstract: The present invention concerns an improved bioreactor with enhanced oxygen transfer. In lieu of the standard impeller and sparger assembly, a rotating gas sparger is used to introduce oxygen into the reactor. A mechanical drive shaft is coupled to a conduit from which a length of tubing extends. A source of pressurized gas is fluidly coupled to the tubing, which tubing is rotated via the mechanical drive shaft. The rotating tubing has a variably sized outlet for introducing oxygen bubbles into the liquid medium of the reactor, the bubbles providing both mechanical agitation and oxygen transfer due to the rotation of the tubing.
    Type: Application
    Filed: September 16, 2020
    Publication date: March 17, 2022
    Inventor: Patrick Power
  • Patent number: 11267845
    Abstract: Compounds that modulate the conversion of AMP to adenosine by 5?-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5?-nucleotidase, ecto is also provided.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: March 8, 2022
    Assignee: ARCUS BIOSCIENCES, INC.
    Inventors: Jaroslaw Kalisiak, Kenneth V. Lawson, Manmohan Reddy Leleti, Erick Allen Lindsey, Dillon Harding Miles, Eric Newcomb, Jay Patrick Powers, Ehesan Ul Sharif
  • Patent number: 11242319
    Abstract: Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: February 8, 2022
    Assignee: Flexus Biosciences, Inc.
    Inventors: Hilary Plake Beck, Juan Carlos Jaen, Maksim Osipov, Jay Patrick Powers, Maureen Kay Reilly, Hunter Paul Shunatona, James Ross Walker, Mikhail Zibinsky, James Aaron Balog, David K. Williams, Weiwei Guo
  • Patent number: 11236048
    Abstract: The disclosure is directed to improved methods for preparing substituted quinolinylcyclohexylpropanamide compounds.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: February 1, 2022
    Assignee: Bristol-Myers Squibb Company
    Inventors: Albert J. Delmonte, Benjamin M. Cohen, Kenneth Joseph Fraunhoffer, Sergei Kolotuchin, Francisco Gonzalez-Bobes, Gregory Louis Beutner, Adam Joseph Freitag, Michael Scott Bultman, Yu Fan, Prantik Maity, Ian Scott Young, Hilary Plake Beck, Maksim Osipov, Jay Patrick Powers, Maureen Kay Reilly, Hunter Paul Shunatona, James Ross Walker, Mikhail Zibinsky
  • Patent number: 11236049
    Abstract: The present disclosure relates to amorphous and crystalline forms of (R)-N-(4-chlorophenyl)-2-((1S,4S)-4-(6-fluoro-quinolin-4-yl) cyclohexyl)propanamide and its salts and hydrates, processes for their production, pharmaceutical compositions comprising them, and methods of treatment using them.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: February 1, 2022
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jay Patrick Powers, Hilary Plake Beck, Maksim Osipov, Maureen Kay Reilly, Hunter Paul Shunatona, James Ross Walker, Mikhail Zibinsky, Tamar Rosenbaum, Ian Scott Young, Jennifer Nelson, Petinka Vlahova
  • Publication number: 20220018477
    Abstract: A water main tapping device and method includes a saddle body including an arcuate portion between a first end and a second end, wherein the saddle body includes a saddle opening at a location between the first end and the second end, and a corporation stop body formed integrally with and extending from the saddle body. The corporation stop body includes a base with an inlet cavity in fluid communication with the saddle opening, a housing extending from the base and having a valve cavity in which a rotatable valve is positioned and which is in fluid communication with the inlet cavity, and a connector end extending from the housing and including an outlet in fluid communication with the valve cavity.
    Type: Application
    Filed: September 30, 2021
    Publication date: January 20, 2022
    Inventor: Patrick Powers
  • Patent number: 11220492
    Abstract: A compound that is an inhibitor of at least one of the A2A and A2B adenosine receptors having Formula (I) and compositions containing the compound and methods for synthesizing the compound, are described herein. The use of such compound and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by the adenosine A2A receptor and/or the adenosine A2B receptor.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: January 11, 2022
    Assignee: ARCUS BIOSCIENCES, INC.
    Inventors: Manmohan Reddy Leleti, Dillon Harding Miles, Jay Patrick Powers, Brandon Reid Rosen, Ehesan Ul Sharif
  • Patent number: 11216774
    Abstract: Systems and methods are disclosed for packing optimization and visualization.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: January 4, 2022
    Assignee: BENESHIP LLC
    Inventors: Patrick Powers, James Malley
  • Publication number: 20210269422
    Abstract: The present invention provides solid forms, solvates and hydrates of 3-[2-amino-6-(1-{[6-(2-hydroxypropan-2-yl)pyridine-2-yl]methyl}-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl]-2-methylbenzonitrile, and methods of making and using the same.
    Type: Application
    Filed: July 17, 2019
    Publication date: September 2, 2021
    Inventors: Jenna Leigh Jeffrey, Manmohan Reddy Leleti, Dillon Harding Miles, Jay Patrick Powers
  • Patent number: 11058704
    Abstract: Compounds that modulate the conversion of AMP to adenosine by 5?-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5?-nucleotidase, ecto is also provided.
    Type: Grant
    Filed: October 2, 2017
    Date of Patent: July 13, 2021
    Assignee: ARCUS BIOSCIENCES, INC.
    Inventors: Laurent Pierre Paul Debien, Jaroslaw Kalisiak, Kenneth V. Lawson, Manmohan Reddy Leleti, Erick Allen Lindsey, Dillon Harding Miles, Eric Newcomb, Jay Patrick Powers, Brandon Reid Rosen, Ehesan Ul Sharif
  • Patent number: 11045472
    Abstract: Compounds of Formula I that inhibit at least one of the A2A and A2B adenosine receptors, and compositions containing compounds of Formula I and methods for synthesizing compounds of Formula I, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by the adenosine A2A receptor and/or the adenosine A2B receptor.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: June 29, 2021
    Assignee: ARCUS BIOSCIENCES, INC.
    Inventors: Manmohan Reddy Leleti, Dillon Harding Miles, Jay Patrick Powers, Brandon Reid Rosen, Ehesan Ul Sharif, Rhiannon Thomas-Tran
  • Patent number: 11001603
    Abstract: Compounds that modulate the conversion of AMP to adenosine by 5?-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5?-nucleotidase, ecto is also provided.
    Type: Grant
    Filed: September 1, 2020
    Date of Patent: May 11, 2021
    Assignee: ARCUS BIOSCIENCES, INC.
    Inventors: Laurent Pierre Paul Debien, Juan Carlos Jaen, Jaroslaw Kalisiak, Kenneth V. Lawson, Manmohan Reddy Leleti, Erick Allen Lindsey, Dillon Harding Miles, Eric Newcomb, Jay Patrick Powers, Brandon Reid Rosen, Ehesan Ul Sharif
  • Patent number: 10987322
    Abstract: Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: April 27, 2021
    Assignee: Flexus Biosciences, Inc.
    Inventors: Juan Carlos Jaen, Maksim Osipov, Jay Patrick Powers, Hunter Paul Shunatona, James Ross Walker, Mikhail Zibinsky
  • Patent number: 10981944
    Abstract: Compounds that modulate the conversion of AMP to adenosine by 5?-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5?-nucleotidase, ecto is also provided.
    Type: Grant
    Filed: February 12, 2019
    Date of Patent: April 20, 2021
    Assignee: ARCUS BIOSCIENCES, INC.
    Inventors: Laurent Pierre Paul Debien, Juan Carlos Jaen, Jaroslaw Kalisiak, Kenneth V. Lawson, Manmohan Reddy Leleti, Erick Allen Lindsey, Dillon Harding Miles, Eric Newcomb, Jay Patrick Powers, Brandon Reid Rosen, Ehesan Ul Sharif