Patents by Inventor Patrick S. L. Wong

Patrick S. L. Wong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Controlled release liquid active agent formulation dosage forms
    Publication number: 20020086055
    Abstract: Controlled release of liquid, active agent formulations is provided by dispersing porous particles containing the liquid active agent formulation in osmotic, push-layer dosage forms. The dosage forms may provide for continuous or pulsatile delivery of active agents.
    Type: Application
    Filed: December 14, 2001
    Publication date: July 4, 2002
    Inventors: Patrick S. L. Wong, David E. Edgren, Liang C. Dong, Crystal Pollock-Dove
  • Antiviral medication
    Publication number: 20020071863
    Abstract: A pharmaceutical composition comprising a liquid antiviral formulation is disclosed. Additionally, a dosage form and a method for administering an antiviral pharmaceutical composition are disclosed.
    Type: Application
    Filed: December 8, 2000
    Publication date: June 13, 2002
    Inventors: Liang C. Dong, Steven D. Espinal, Patrick S.-L. Wong, Paul R. Magruder
  • Method of fabricating a banded prolonged release active agent dosage form
    Patent number: 6365183
    Abstract: The present invention is directed to an active agent dosage form and methods of its fabrication which is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has on its surface one or more insoluble bands located in complementary grooves. The invention is also directed to articles of manufacture, methods and systems for fabricating the active agent dosage form.
    Type: Grant
    Filed: March 23, 1999
    Date of Patent: April 2, 2002
    Assignee: ALZA Corporation
    Inventors: David E. Edgren, Patrick S.-L. Wong, Francisco Jao, Yolanda M. Puga
  • Method for lowering blood glucose
    Patent number: 6361795
    Abstract: The invention disclosed comprises a method for administering the antidiabetic drug glipizide to a patient in need of glipizide in need of antidiabetic therapy.
    Type: Grant
    Filed: January 11, 1994
    Date of Patent: March 26, 2002
    Assignee: Alza Corporation
    Inventors: Anthony L. Kuczynski, Atul Devolatt Ayer, Patrick S. L. Wong
  • Controlled release liquid active agent formulation dosage forms
    Patent number: 6342249
    Abstract: Controlled release of liquid, active agent formulations is provided by dispersing porous particles containing the liquid active agent formulation in osmotic, push-layer dosage forms. The dosage forms may provide for continuous or pulsatile delivery of active agents.
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: January 29, 2002
    Assignee: Alza Corporation
    Inventors: Patrick S. -L. Wong, David E. Edgren, Liang C. Dong, Crystal Pollock-Dove
  • Antidepressant therapy
    Publication number: 20010055614
    Abstract: An osmotic dosage from is disclosed for delivering an antidepressant for treating depression in a patient in need of antidepressant therapy.
    Type: Application
    Filed: August 15, 2001
    Publication date: December 27, 2001
    Inventors: Sylvia Seroff, Patrick S.-L. Wong, Atul D. Ayer
  • Oral delivery of discrete units
    Patent number: 6333050
    Abstract: The present invention is directed to an oral active agent delivery system and method for delivering discrete units of an active agent formulation to a patient. An active agent formulation chamber containing the active agent formulation and having a fluid passing active agent formulation retainer is placed at a first end into a fluid and at a second end into a patient's mouth. The active agent is delivered when the patient sips on the second end of the chamber.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: December 25, 2001
    Assignee: Alza Corporation
    Inventors: Patrick S.-L. Wong, Howard B. Rosen, Nathan Roth, Phyllis I. Gardner
  • Osmotically-driven fluid dispenser and composition
    Publication number: 20010047161
    Abstract: Improvements in a mini-osmotic pump and coating compositions are described. The dispensing pump includes an inner fluid-filled bag encased by an osmotic layer and outer, semi-permeable membrane. The inner bag is formed with an arcuate edge at the open end of the bag to inhibit formation of fissures in the outer membrane in this edge region. The coating compositions include cellulose acetate butyrate, cellulose acetate propionate, and polymethylmethacrylate polymers, optionally mixed with ethyl cellulose in acetone based solvent systems.
    Type: Application
    Filed: January 30, 2001
    Publication date: November 29, 2001
    Inventors: Patrick S.L. Wong, Nipun Davar
  • Device for enhancing transdermal agent flux
    Patent number: 6322808
    Abstract: A device (3) comprising a sheet member (6) having a plurality of microprotrusions (4) for penetrating the skin and a rigid support (15) contacting and extending across the sheet member (6) for transmitting an applied force evenly across the length and width of the sheet member (6) to reproducibly and reliably penetrate the skin with the microprotrusions (4).
    Type: Grant
    Filed: December 9, 1998
    Date of Patent: November 27, 2001
    Assignee: ALZA Corporation
    Inventors: Joseph Creagan Trautman, Patrick S.-L. Wong, Peter E. Daddona, Hyunok Lynn Kim, Michael G. Zuck
  • Banded prolonged release active agent dosage form
    Patent number: 6316028
    Abstract: The present invention is directed to an active agent dosage that is useful for the prolonged delivery of an active agent formulation to fluid environment of use. The active agent dosage form is a matrix that has an insoluble material circumscribing a portion of the surface of the matrix. The invention is also directed to a method of making the active agent dosage form.
    Type: Grant
    Filed: August 31, 2000
    Date of Patent: November 13, 2001
    Inventors: Patrick S.-L. Wong, David Emil Edgren, Liang C. Dong, Vincent Joseph Ferrari
  • Conversion of liquid filled gelatin capsules into controlled release systems by multiple coatings
    Publication number: 20010036472
    Abstract: A dosage form comprising a gelatin capsule formed with a composite wall and containing a liquid, active agent formulation where the wall comprises a barrier layer formed over the external surface of the gelatin capsule, an expandable layer formed over the barrier layer and a semipermeable layer formed over the expandable layer is described. The dosage forms and methods provide for the conversion of standard gelatin, liquid formulation capsules into controlled, release dosage forms that permit the controlled release of the active agent into the environment of use over time.
    Type: Application
    Filed: May 25, 2001
    Publication date: November 1, 2001
    Inventors: Patrick S.-L. Wong, Liang C. Dong, Jiansheng Wan
  • Method for providing sustained antiepileptic therapy
    Patent number: 6287598
    Abstract: This invention pertains to a dosage form for the management of epilepsies wherein the dosage form comprises administering valproic acid or a valproic acid derivative at a continuous rate over an extended time.
    Type: Grant
    Filed: May 28, 1993
    Date of Patent: September 11, 2001
    Assignee: Alza Corporation
    Inventors: Atul Devatt Ayer, Richard L.-C. Yieh, Brenda J. Pollock, Patrick S.-L. Wong
  • Extended release dosage form
    Patent number: 6245357
    Abstract: A dosage form comprising a composition comprising a drug surrounded by an interior and an exterior wall with an exit for administering the drug to a patient; and a method of using the dosage form are disclosed for an indicated therapy.
    Type: Grant
    Filed: February 12, 1999
    Date of Patent: June 12, 2001
    Assignee: Alza Corporation
    Inventors: David E. Edgren, Shu Li, Gurdish Kaur Bhatti, Patrick S. L. Wong, Robert R. Skluzacek
  • Oral delivery of discrete units
    Publication number: 20010002262
    Abstract: The present invention is directed to an oral active agent delivery system and method for delivering discrete units of an active agent formulation to a patient. An active agent formulation chamber containing the active agent formulation and having a fluid passing active agent formulation retainer is placed at a first end into a fluid and at a second end into a patient's mouth. The active agent is delivered when the patient sips on the second end of the chamber.
    Type: Application
    Filed: January 19, 2001
    Publication date: May 31, 2001
    Inventors: Patrick S. L. Wong, Howard B. Rosen, Nathan Roth, Phyllis I. Gardner
  • Dosage form comprising liquid formulation
    Publication number: 20010001280
    Abstract: A dosage form is disclosed comprising a drug formulation that self-emulsifies in said dosage form.
    Type: Application
    Filed: December 19, 2000
    Publication date: May 17, 2001
    Inventors: Liang-Chang Dong, Steven Espinal, Patrick S.L. Wong
  • Flow controller configurations for an active agent delivery device
    Patent number: 6224908
    Abstract: Oral active agent delivery system having improved flow controllers. A hollow tubular member containing the active agent formulation and having a fluid passing controller is placed at one end into a fluid and at a second end into a patient's mouth. The active agent is delivered when the patient sips on the end of the chamber. The improved controllers prevent leakage of the active agent formulation.
    Type: Grant
    Filed: May 24, 2000
    Date of Patent: May 1, 2001
    Assignee: Alza Corporation
    Inventors: Patrick S.-L. Wong, Vincent J. Ferrari, Jeffrey W. Etter, Miriam A. Martin, Nathan Roth, Christopher M. G. Ohms, Andrew I. Poutiatine, James Horvath
  • Oral delivery of discrete units
    Patent number: 6210713
    Abstract: The present invention is an oral active agent delivery system and method for delivering discrete units of an active agent formulation to a patient. An active agent formulation chamber containing the active agent formulation and having a fluid passing active agent formulation retainer is placed at a first end into a fluid and at a second end into a patient's mouth. The active agent is delivered when the patient sips on the second end of the chamber.
    Type: Grant
    Filed: February 25, 2000
    Date of Patent: April 3, 2001
    Assignee: Alza Corporation
    Inventors: Patrick S.-L. Wong, Howard B. Rosen, Nathan Roth, Phyllis I. Gardner
  • Dosage form comprising a capsule
    Patent number: 6183466
    Abstract: A dosage form is disclosed comprising a wall that defines an injection-molded compartment housing a capsule comprising a drug formulation.
    Type: Grant
    Filed: June 25, 1999
    Date of Patent: February 6, 2001
    Assignee: Alza Corporation
    Inventors: Patrick S. L. Wong, Felix Theeuwes, Vincent J. Ferrari, Liang C. Dong
  • Dosage form comprising liquid formulation
    Patent number: 6174547
    Abstract: A dosage form is disclosed comprising a drug formulation that self-emulsifies in said dosage form.
    Type: Grant
    Filed: July 14, 1999
    Date of Patent: January 16, 2001
    Assignee: ALZA Corporation
    Inventors: Liang-Chang Dong, Steven Espinal, Patrick S. L. Wong
  • Injection-moldable composition and article of manufacture comprising same
    Patent number: 6153678
    Abstract: Polymeric compositions are disclosed comprising a poly(caprolactone), a poly(alkylene oxide), a poly(oxyethylenated fatty acid ester), or a poly(oxyethylenated fatty acid), or a poly(oxyethylene-co-oxypropylene).
    Type: Grant
    Filed: October 6, 1998
    Date of Patent: November 28, 2000
    Assignee: Alza Corporation
    Inventors: Liang-Chang Dong, Crystal Pollock, Patrick S.-L. Wong, Keru O. Shafi, Vincent J. Ferrari, Ted Smith