Patents by Inventor Patrick SAGMEISTER

Patrick SAGMEISTER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fermentation process
    Patent number: 11377677
    Abstract: A method for producing a recombinant protein of interest (POI) is provided, comprising the steps of (a) culturing cells in a cell culture medium to express said POI by adding a feed comprising at least one substrate to said cell culture, (b) applying a feeding strategy based on calculating, setting and optionally controlling the specific substrate uptake rate qs of the cells during the induction phase and/or production phase of the POI, wherein qs is set to be close to the maintenance rate of the cell culture; and (c) isolating said POI from the cell culture.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: July 5, 2022
    Assignee: LONZA LTD
    Inventors: Wieland Reichelt, Christoph Herwig, Julian Kager, Patrick Sagmeister, Matthias Funke
  • Fed-batch process for the production of bacterial ghosts
    Patent number: 10526574
    Abstract: The invention relates to a fed-batch process for the production of bacterial ghosts based on the decoupling of the lytic gene expression and actual lysis of bacterial cells.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: January 7, 2020
    Assignee: Bird-C GmbH & Co. KG
    Inventors: Werner Lubitz, Christian Herwig, Timo Langemann, Patrick Sagmeister
  • IMPROVED FERMENTATION PROCESS
    Publication number: 20190093142
    Abstract: A method for producing a recombinant protein of interest (POI) is provided, comprising the steps of (a) culturing cells in a cell culture medium to express said POI by adding a feed comprising at least one substrate to said cell culture, (b) applying a feeding strategy based on calculating, setting and optionally controlling the specific substrate uptake rate qs of the cells during the induction phase and/or production phase of the POI, wherein qs is set to be close to the maintenance rate of the cell culture; and (c) isolating said POI from the cell culture.
    Type: Application
    Filed: March 2, 2017
    Publication date: March 28, 2019
    Inventors: Wieland REICHELT, Christoph HERWIG, Julian KAGER, Patrick SAGMEISTER, Matthias FUNKE
  • FED-BATCH PROCESS FOR THE PRODUCTION OF BACTERIAL GHOSTS
    Publication number: 20180201895
    Abstract: The invention relates to a fed-batch process for the production of bacterial ghosts based on the decoupling of the lytic gene expression and actual lysis of bacterial cells.
    Type: Application
    Filed: February 20, 2015
    Publication date: July 19, 2018
    Applicant: BIRD-C GMBH & CO KG
    Inventors: Werner LUBITZ, Christian HERWIG, Timo LANGEMANN, Patrick SAGMEISTER