Patents by Inventor Patrick Saulnier

Patrick Saulnier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9522121
    Abstract: The invention relates to a composition comprising in an aqueous phase, particles having a diameter in the range of 20 to 500 nm, said particles containing:—an oil phase;—in said oil phase,—an aqueous droplet, or—a nanocapsule (NC) comprising:—an aqueous core, and—a polymeric shell or a shell composed of an amphiphilic substance; and—a surfactant. This composition is particularly useful for encapsulating hydrophilic and/or lipophilic substances.
    Type: Grant
    Filed: September 18, 2008
    Date of Patent: December 20, 2016
    Assignee: UNIVERSITE D'ANGERS
    Inventors: Nicolas Anton, Patrick Saulnier, Jean-Pierre Benoit
  • Patent number: 9492398
    Abstract: A composition, an encapsulated composition and/or nanoparticles comprising at least one essential oil having a large spectrum antibacterial, antiparasitic, antifungal activity and/or a plant antipathogen, optionally at least one antibiotic and optionally a pharmaceutically acceptable carrier is disclosed. Methods for treating infectious diseases and especially bacterial, parasitic, fungal and/or plant infectious by using this composition, encapsulated composition and/or nanoparticles are also disclosed.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: November 15, 2016
    Assignees: Eydo Pharma, Institut National de la Sante et de la Recherche Medicale, Université d'Angers
    Inventors: Elisabeth Rossines, Marie Laure Joly-Guillou, Patrick Saulnier, Jean Pierre Benoit
  • Patent number: 9333180
    Abstract: The invention relates to nanocapsules with a liquid lipidic core and a solid lipidic shell, the lipidic core being loaded with at least one water-soluble or water-dispersible ingredient, said ingredient being present in the form of a reverse micellar system.
    Type: Grant
    Filed: June 11, 2008
    Date of Patent: May 10, 2016
    Assignees: UNIVERSITE D'ANGERS, INSERM TRANSFERT
    Inventors: Patrick Saulnier, Jean-Pierre Benoit, Nicolas Anton
  • Patent number: 9302241
    Abstract: Provided is a method for preparing nanocapsules having a liquid lipid core and a solid shell and charged in their lipid core with at least one hydrophilic active agent involving combining microemulsions where the active agent remains in the hydrophilic phase of a first microemulsion and chill-hardening the mixture to obtain the nanocapsules charged with the hydrophilic active agent. The nanocapsules comprise the lipid core which is liquid at room temperature and the nanocapsules are encapsulated in a film which is solid at room temperature.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: April 5, 2016
    Assignees: UNIVERSITE D'ANGERS, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Jean-Pierre Benoit, Olivier Thomas, Patrick Saulnier, Alyaa Adel Ramadan
  • Patent number: 9005666
    Abstract: A process for preparing nanocapsules with a liquid lipid core and a solid lipid shell, charged with at least one active agent. The process contains at least the steps of formulating a microemulsion by phase inversion of an emulsion, totally or partially forming from at least one active agent a second composition different than the microemulsion, placing the microemulsion in contact with the second composition under conditions suitable for interaction of the active agent with the microemulsion, and chill-hardening the microemulsion that has interacted with the active agent, to obtain the nanocapsules.
    Type: Grant
    Filed: June 11, 2008
    Date of Patent: April 14, 2015
    Assignees: L'Universite d'Angers, Inserm Transfert
    Inventors: Patrick Saulnier, Jean-Pierre Benoit, Nicolas Anton
  • Publication number: 20140045692
    Abstract: A composition, an encapsulated composition and/or nanoparticles comprising at least one essential oil having a large spectrum antibacterial, antiparasitic, antifungal activity and/or a plant antipathogen, optionally at least one antibiotic and optionally a pharmaceutically acceptable carrier is disclosed. Methods for treating infectious diseases and especially bacterial, parasitic, fungal and/or plant infectious by using this composition, encapsulated composition and/or nanoparticles are also disclosed.
    Type: Application
    Filed: February 24, 2012
    Publication date: February 13, 2014
    Inventors: Elisabeth Rossines, Marie Laure Joly-Guillou, Patrick Saulnier, Jean Pierre Benoit
  • Publication number: 20120027825
    Abstract: The present invention relates to a useful method for preparing nanocapsules having a liquid lipid core and a solid shell and charged with at least one active agent having a hydrophilic character, said method comprising at least the steps consisting in: i) providing at least a first microemulsion having a water-in-oil character, stabilized by at least one lipophilic surfactant and containing in its hydrophilic phase at least one active agent having a hydrophilic character, providing at least a second microemulsion, separate from the first microemulsion, formulated by phase inversion of an emulsion and stabilized by at least one heat-sensitive, nonionic hydrophilic surfactant; iii) adding said first microemulsion to said second microemulsion under conditions propitious for the formation of a novel microemulsion architecture in which said hydrophilic active agent remains present in the hydrophilic phase of the first microemulsion; and iv) chill-hardening the mixture formed in the previous step, so as to obtain n
    Type: Application
    Filed: December 11, 2009
    Publication date: February 2, 2012
    Applicants: INST NAT DE LA SANTE ET DE LA RECHER. MED (INSERM), UNIVERSITE D'ANGERS
    Inventors: Jean-Pierre Benoit, Olivier Thomas, Patrick Saulnier, Alyaa Adel Ramadan
  • Patent number: 8057823
    Abstract: The invention concerns nanocapsules, in particular with an average size less than 50 nm, consisting of an essentially lipid core liquid or semiliquid at room temperature, coated with an essentially lipid film solid at room temperature having a thickness of 2-10 nm. The invention also concerns a method for preparing same which consists in producing a reverse phase of an aqueous emulsion brought about by several temperature raising and lowering cycles. Said lipid nanocapsules are particularly designed for producing a medicine.
    Type: Grant
    Filed: March 2, 2001
    Date of Patent: November 15, 2011
    Assignees: Universite d'Angers, Ethypharm S.A.
    Inventors: Béatrice Heurtault, Patrick Saulnier, Jean-Pierre Benoit, Jacques-Emile Proust, Brigitte Pech, Joël Richard
  • Publication number: 20100297247
    Abstract: The invention relates to a composition comprising in an aqueous phase, particles having a diameter in the range of 20 to 500 nm, said particles containing:—an oil phase;—in said oil phase,—an aqueous droplet, or—a nanocapsule (NC) comprising:—an aqueous core, and—a polymeric shell or a shell composed of an amphiphilic substance; and—a surfactant. This composition is particularly useful for encapsulating hydrophilic and/or lipophilic substances.
    Type: Application
    Filed: September 18, 2008
    Publication date: November 25, 2010
    Applicant: Institut National de la Sante et de la Recherche Medicale (Inserm)
    Inventors: Nicolas Anton, Patrick Saulnier, Jean-Pierre Benoit
  • Publication number: 20100266676
    Abstract: The invention relates to nanocapsules with a liquid lipidic core and a solid lipidic shell, the lipidic core being loaded with at least one water-soluble or water-dispersible ingredient, said ingredient being present in the form of a reverse micellar system.
    Type: Application
    Filed: June 11, 2008
    Publication date: October 21, 2010
    Applicant: UNIVERSITE D' ANGERS
    Inventors: Patrick Saulnier, Jean-Pierre Benoit, Nicolas Anton
  • Publication number: 20100233275
    Abstract: The present invention relates to a method for use in the preparation of nanocapsules which have a liquid lipid core and a solid lipid shell and which are loaded with at least one active agent, wherein said method comprises at least the steps consisting in providing a microemulsion formulated by phase inversion of an emulsion, providing a second composition, distinct from said microemulsion and completely or partly formed from at least one active agent, placing said microemulsion in the presence of said second composition under conditions suitable for the interaction of said active agent with said microemulsion and annealing said microemulsion having interacted with said active agent in such a way as to obtain said nanocapsules. The invention also relates to a corresponding kit.
    Type: Application
    Filed: June 11, 2008
    Publication date: September 16, 2010
    Applicant: UNIVERSITE D' ANGERS
    Inventors: Patrick Saulnier, Jean-Pierre Benoit, Nicolas Anton
  • Publication number: 20090238865
    Abstract: The invention concerns nanocapsules, in particular with an average size less than 50 nm, consisting of an essentially lipid core liquid or semiliquid at room temperature, coated with an essentially lipid film solid at room temperature having a thickness of 2-10 nm. The invention also concerns a method for preparing same which consists in producing a reverse phase of an aqueous emulsion brought about by several temperature raising and lowering cycles. Said lipid nanocapsules are particularly designed for producing a medicine.
    Type: Application
    Filed: May 29, 2009
    Publication date: September 24, 2009
    Inventors: Beatrice Heurtault, Patrick Saulnier, Jean-Pierre Benoit, Jacques-Emile Proust, Brigitte Pech, Joel Richard
  • Publication number: 20030152635
    Abstract: The invention concerns nanocapsules, in particular with an average size less than 50 nm, consisting of an essentially lipid core liquid or semiliquid at room temperature, coated with an essentially lipid film solid at room temperature having a thickness of 2-10 nm. The invention also concerns a method for preparing same which consists in producing a reverse phase of an aqueous emulsion brought about by several temperature raising and lowering cycles. Said lipid nanocapsules are particularly designed for producing a medicine.
    Type: Application
    Filed: November 26, 2002
    Publication date: August 14, 2003
    Inventors: Beatrice Heurtault, Patrick Saulnier, Jean-Pierre Benoit, Jacques-Emile Proust, Brigitte Pech, Joel Richard
  • Patent number: 6541246
    Abstract: Method for detecting and for quantifying adenoviruses by polymerase chain reaction (PCR). The method makes it possible to detect, in a single reaction, the various adenovirus serotypes and to quantify very low amounts.
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: April 1, 2003
    Assignee: Gencell S.A.
    Inventors: Michel Vidaud, Eric Gautier, Patrick Saulnier
  • Publication number: 20020061516
    Abstract: Method for detecting and for quantifying adenoviruses by polymerase chain reaction (PCR). The method makes it possible to detect, in a single reaction, the various adenovirus serotypes and to quantify very low amounts.
    Type: Application
    Filed: February 8, 2001
    Publication date: May 23, 2002
    Inventors: Michel Vidaud, Eric Gautier, Patrick Saulnier