Patents by Inventor Patrick T. Gunning

Patrick T. Gunning has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITION FOR KRAS MODIFICATIONS
    Publication number: 20240092756
    Abstract: Provided herein are compounds binding to KRAS protein or a mutant thereof, pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases.
    Type: Application
    Filed: November 18, 2021
    Publication date: March 21, 2024
    Inventors: Patrick T. GUNNING, Jeff OMEARA, Siawash AHMAR, Graham L. SIMPSON, Peter HUNT, David Alexander ROSA, Ji Sung PARK
  • BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF
    Publication number: 20240018153
    Abstract: Provided herein are benzenesulfonamide compounds, pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases.
    Type: Application
    Filed: November 18, 2021
    Publication date: January 18, 2024
    Inventors: Patrick T. GUNNING, Jeff OMEARA, Siawash AHMAR, Graham L. SIMPSON, Peter HUNT, David Alexander ROSA, Ji Sung PARK
  • PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF
    Publication number: 20230055961
    Abstract: Provided herein are pentafluorobenzenesulfonamide compounds, pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases.
    Type: Application
    Filed: May 19, 2022
    Publication date: February 23, 2023
    Inventors: Dziyana KRASKOUSKAYA, Siawash AHMAR, Patrick T. GUNNING, Jeff OMEARA, David Alexander ROSA, Ji Sung PARK, Graham L. SIMPSON, Ayah ABDELDAYEM
  • BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF
    Publication number: 20220281812
    Abstract: Provided herein are benzenesulfonamide derivatives having Formula (III), pharmaceutical compositions comprising said compounds, and method for using said compounds for disrupting proteins/polypeptides, protein/polypeptide function, and for the treatment of diseases through the disruption of proteins or polypeptides involved in the etiology of the disease. Said compounds comprise fluorinated benzene sulfonamide structures.
    Type: Application
    Filed: July 17, 2020
    Publication date: September 8, 2022
    Inventors: Patrick T. GUNNING, Ji Sung PARK, Siawash AHMAR, Aaron D. CABRAL, Gary K.C. TIN, Sana RASHEED, Ayah ABDELDAYEM, David ARMSTRONG, Geordon A. FRERE, Erica J. QUILATES, David Alexander ROSA, Olga GOZHINA, Jeffrey Alan OMEARA, Graham SIMPSON, Vittoria ZOPPI
  • HALOGENATED PHENYLSULFONAMIDE HYDROXAMIC ACID COMPOUNDS, COMPOSITIONS AND USES THEREOF AS SELECTIVE HDAC6 INHIBITORS
    Publication number: 20220169598
    Abstract: The present application relates to fluorinated benzylsulfonamide hydroxamic acid compounds of Formula I and/or pharmaceutically acceptable salt, solvate and/or prodrug thereof: (I) for use as a inhibitor of HDAC6. The application also relates to methods of treating a disease, disorder or condition using the compounds and compositions of the application.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 2, 2022
    Inventors: Patrick T. Gunning, Olasunkanmi Olaoye, Krimo Toutah, Andrew E. Shouksmith, Justyna M. Shouksmith, Nabanita Nawar, Yasir S. Raouf