Abstract: Various embodiments provide a steering control mechanism, an imaging endoscopy system incorporating a steering control mechanism, and a method of assembling a steering control mechanism. The steering control mechanism is configured for controlling bending of a steering section of an endoscope in a first plane via first and second steering wires. It comprises a first rotational drive wheel comprising first and second drive wheel body portions, the first drive wheel body portion comprising a first drum element coupled to the first steering wire, and the second drive wheel body portion comprising a second drum element coupled to the second steering wire. The rotational drive wheel is configured to provide one-way relative rotation of the first drum element and the second drum element.

Abstract: Various embodiments provide an imaging endoscopy system comprising a hand controller, an insertion section having a proximal end connected to the hand controller and a distal end for insertion into a subject, the distal end having a steering section and a distal tip, and a steering control mechanism comprising a first continuous steering wire. The first continuous steering wire has first and second ends coupled to a user control assembly at the hand controller, and an intermediate portion fixed at the distal tip of the insertion section, thereby defining two steering wire portions extending from the hand controller to the distal tip, said steering wire portions capable of being tensioned to cause bending of the steering section in response to operation of the user control assembly of the hand controller.

Abstract: Various embodiments provide a bendable member for an imaging endoscope and an imaging endoscope incorporating said bendable member. The bendable member comprises a series of constructional elements arranged longitudinally in series along the bendable member and formed integrally with a plurality of living hinge elements that permit bending between adjacent constructional elements, wherein, when the bendable member is straight, a first living hinge element of the plurality of living hinge elements has a different bending stiffness to a second living hinge element of the plurality of living hinge elements.

Abstract: Various embodiments provide an imaging endoscope system and method for assembling an imaging endoscope system from a kit. The imaging endoscope system comprises a base unit, a hand controller, an umbilical section for releasably connecting the base unit and the hand controller, and an insertion section having a proximal end connected to the hand controller and a distal end for insertion into a subject. The base unit is configured for provision of electrical power and one or more fluids to the insertion section via the umbilical section and the hand controller. The umbilical section comprises an umbilical section connector configured to be releasably engageable with a corresponding base unit connector via a single connection action to make at least one mechanical connection, at least one electrical connection, and at least one fluid connection between the umbilical section connector and the base unit connector during said single connection action.

Abstract: An imaging endoscopy system is disclosed, having a base unit, a hand controller, an umbilical section releasably connecting the base unit and the hand controller and an insertion section. The insertion section has a proximal end connected to the hand controller and a distal end for insertion into a subject, the distal end having a steering section and a distal tip. The hand controller includes at least one steering control for controlling bending of the steering section, and wherein the distal tip includes a light source for illumination of a region of tissue of interest and an imaging chip for imaging the region of tissue of interest. The hand controller, umbilical section and insertion section are single use disposable. The base unit is configured to be re-usable.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for training a neural network system used to control an agent interacting with an environment. One of the methods includes receiving a current observation; processing the current observation using a proposal neural network to generate a proposal output that defines a proposal probability distribution over a set of possible actions that can be performed by the agent to interact with the environment; sampling (i) one or more actions from the set of possible actions in accordance with the proposal probability distribution and (ii) one or more actions randomly from the set of possible actions; processing the current observation and each sampled action using a Q neural network to generate a Q value; and selecting an action using the Q values generated by the Q neural network.

Abstract: In Example implementations provide a computer program product to authenticate a set of components associated with a device; the components having associated respective shares (s1..sn) of a private key of a private-key/public key pair (sk,pk); the computer program product comprising: instructions to create a signature from the shares (s1..sn) and a message, m, associated with the components; and instructions to generate authentication data comprising at least the signature for transmitting to an authentication server.

Abstract: Centralized systems execute one or more applications for monitoring and operating a plurality of network enabled medical devices. An indication to start a selected application at the centralized system or at a network enabled medical device is received at the centralized system/network enabled medical device. The selected application may require a license to operate and, at the time the indication is received, may have a first license available. Instead of using the first license, the centralized system/network enabled medical device may determine to inherit at least a portion of a second license to operate the selected application. The centralized system/network enabled medical device may inherit at least the portion of the second license to form an inherited license, where the inherited license enables features of the selected application. Using the inherited license, the selected application is started with the enabled features. Related apparatus, systems, techniques and articles are also described.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for training a neural network system used to control an agent interacting with an environment. One of the methods includes receiving a current observation; processing the current observation using a proposal neural network to generate a proposal output that defines a proposal probability distribution over a set of possible actions that can be performed by the agent to interact with the environment; sampling (i) one or more actions from the set of possible actions in accordance with the proposal probability distribution and (ii) one or more actions randomly from the set of possible actions; processing the current observation and each sampled action using a Q neural network to generate a Q value; and selecting an action using the Q values generated by the Q neural network.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for training a policy neural network for use in controlling an agent using relative variational intrinsic control. In one aspect, a method includes: selecting a skill from a set of skills; generating a trajectory by controlling the agent using the policy neural network while the policy neural network is conditioned on the selected skill; processing an initial observation and a last observation using a relative discriminator neural network to generate a relative score; processing the last observation using an absolute discriminator neural network to generate an absolute score; generating a reward for the trajectory from the absolute score corresponding to the selected skill and the relative score corresponding to the selected skill; and training the policy neural network on the reward for the trajectory.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for selecting actions to be performed by an agent that interacts with an environment. In one aspect, a system comprises: an action selection subsystem that selects actions to be performed by the agent using an action selection policy generated using an action selection neural network; a reward subsystem that is configured to: receive an observation characterizing a current state of the environment and an observation characterizing a goal state of the environment; generate a reward using an embedded representation of the observation characterizing the current state of the environment and an embedded representation of the observation characterizing the goal state of the environment; and a training subsystem that is configured to train the action selection neural network based on the rewards generated by the reward subsystem using reinforcement learning techniques.

Abstract: Systems are provided for compact implantable multi-site optical stimulation and/or combined electrical and optical stimulation of spinal cord, brain, dorsal root ganglion, peripheral nerve, or other tissue. High-power LEDs or other light-emitting elements are provided at the site of stimulation, avoiding complex fiber optics or other means for coupling light from a distant laser along a stimulator to target tissue. Colocation of electrical stimulation contacts and light emitters allows the same tissue to be stimulated electrically and optically, at the same time or according to an alternating or other pattern of combined electrical and optical stimulation. These stimulators can be used as part of permanently implanted systems and/or as part of temporary, percutaneous stimulator systems. Optical and/or combined electrical and optical stimulation can be provided for pain relief, to encourage wound healing in nervous or non-nervous tissue, or to provide other clinical benefits.

Abstract: A procedure for producing a liquid fertilizing product from a biosolids cake that has been de-watered to a biosolids content of 18% or more. The procedure includes positioning a process amount of the biosolids cake in a reactor vessel, heating the biosolids cake process amount, and adding a quantity of an alkali and mixing it into the process amount of the biosolids cake to form a reactor mixture. The reactor mixture incubated for a period, and then cooled. The alkali includes pH-raising and hydrolysis-procuring components. The quantity of alkali in relating to the biosolids process amount is sufficient that a residual amount of the alkali remains in the cooled reactor mixture, the pH of the reactor mixture remains at a saturation level during and after the incubation period, and the cooled reaction mixture is pumpable.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for selecting actions to be performed by an agent that interacts with an environment. In one aspect, a system comprises: an action selection subsystem that selects actions to be performed by the agent using an action selection policy generated using an action selection neural network; a reward subsystem that is configured to: receive an observation characterizing a current state of the environment and an observation characterizing a goal state of the environment; generate a reward using an embedded representation of the observation characterizing the current state of the environment and an embedded representation of the observation characterizing the goal state of the environment; and a training subsystem that is configured to train the action selection neural network based on the rewards generated by the reward subsystem using reinforcement learning techniques.

Abstract: Centralized systems execute one or more applications for monitoring and operating a plurality of network enabled medical devices. An indication to start a selected application at the centralized system or at a network enabled medical device is received at the centralized system/network enabled medical device. The selected application may require a license to operate and, at the time the indication is received, may have a first license available. Instead of using the first license, the centralized system/network enabled medical device may determine to inherit at least a portion of a second license to operate the selected application. The centralized system/network enabled medical device may inherit at least the portion of the second license to form an inherited license, where the inherited license enables features of the selected application. Using the inherited license, the selected application is started with the enabled features. Related apparatus, systems, techniques and articles are also described.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for selecting actions to be performed by an agent that interacts with an environment. In one aspect, a system comprises: an action selection subsystem that selects actions to be performed by the agent using an action selection policy generated using an action selection neural network; a reward subsystem that is configured to: receive an observation characterizing a current state of the environment and an observation characterizing a goal state of the environment; generate a reward using an embedded representation of the observation characterizing the current state of the environment and an embedded representation of the observation characterizing the goal state of the environment; and a training subsystem that is configured to train the action selection neural network based on the rewards generated by the reward subsystem using reinforcement learning techniques.

Abstract: Centralized systems execute one or more applications for monitoring and operating a plurality of network enabled medical devices. An indication to start a selected application at the centralized system or at a network enabled medical device is received at the centralized system/network enabled medical device. The selected application may require a license to operate and, at the time the indication is received, may have a first license available. Instead of using the first license, the centralized system/network enabled medical device may determine to inherit at least a portion of a second license to operate the selected application. The centralized system/network enabled medical device may inherit at least the portion of the second license to form an inherited license, where the inherited license enables features of the selected application. Using the inherited license, the selected application is started with the enabled features. Related apparatus, systems, techniques and articles are also described.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for training a neural network system used to control an agent interacting with an environment. One of the methods includes receiving a current observation; processing the current observation using a proposal neural network to generate a proposal output that defines a proposal probability distribution over a set of possible actions that can be performed by the agent to interact with the environment; sampling (i) one or more actions from the set of possible actions in accordance with the proposal probability distribution and (ii) one or more actions randomly from the set of possible actions; processing the current observation and each sampled action using a Q neural network to generate a Q value; and selecting an action using the Q values generated by the Q neural network.

Abstract: A gate-latching assembly is configured for utilization with a gate assembly. The gate assembly includes a stationary gate post configured to be mounted to, and to extend from, a working surface once the stationary gate post is mounted to the working surface, and in which the gate assembly also includes a movable gate door configured to be movable relative to the stationary gate post. There is provided a combination for utilization with the gate assembly. The combination includes any one of (A) a striker base assembly and a striker member, (B) a latch base assembly and a latch assembly, and/or (C) a striker base assembly, a striker member, a latch base assembly and a latch assembly.

Abstract: The invention provides a process for the drying and re-hydration of high solids Biosolids cake to be converted into a pumpable organic liquid fertilizer. This process may be carried out at ambient pressure without aggressive shearing of the mixture of added process water and the high solids Biosolids cake. The drying step removes the bound water, while the re-hydration step includes mixing which breaks down the particulate matter to produce a fairly homogeneous suspension.