Patents by Inventor Patrick WILKINSON

Patrick WILKINSON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240294884
    Abstract: Provided are vaccines, polypeptides and polynucleotides based on mutant CALR and JAK2 sequences, vectors, host cells, viruses, and methods of making and using them. The disclosure also provides methods of inducing an immune response and methods of treating, preventing, reducing a risk of onset or delaying the onset of a clinical condition characterized by an expression of JAK2V617F or CALR exon 9 mutant, or both JAK2V617F and CALR exon 9 mutant, wherein the method comprises a plurality of administrations of any of the compositions comprising polynucleotides, polypeptides or vectors disclosed herein.
    Type: Application
    Filed: May 14, 2024
    Publication date: September 5, 2024
    Inventors: Ricardo ATTAR, Jason DEHART, Selina KHAN, Vinod KRISHNA, Jenifer LUM, Christian MAINE, Barbara SANDERS, Manuel Alejandro SEPULVEDA, Patrick WILKINSON, Roland ZAHN
  • Patent number: 12018289
    Abstract: Provided are vaccines, polypeptides and polynucleotides based on mutant CALR and JAK2 sequences, vectors, host cells, viruses, and methods of making and using them. The disclosure also provides methods of inducing an immune response and methods of treating, preventing, reducing a risk of onset or delaying the onset of a clinical condition characterized by an expression of JAK2V617F or CALR exon 9 mutant, or both JAK2V617F and CALR exon 9 mutant, wherein the method comprises a plurality of administrations of any of the compositions comprising polynucleotides, polypeptides or vectors disclosed herein.
    Type: Grant
    Filed: November 13, 2020
    Date of Patent: June 25, 2024
    Assignee: Janssen Biotech, Inc.
    Inventors: Ricardo Attar, Jason Dehart, Selina Khan, Vinod Krishna, Jenifer Lum, Christian Maine, Barbara Sanders, Manuel Alejandro Sepulveda, Patrick Wilkinson, Roland Zahn
  • Publication number: 20230285548
    Abstract: Disclosed herein are methods of treating or preventing a myeloproliferative disease, a cancer, or a cardiovascular disease, and methods of inducing an immune response, in a subject having a JAK2V617F substitution and/or a CALR exon 9 mutation.
    Type: Application
    Filed: December 13, 2022
    Publication date: September 14, 2023
    Inventors: Patrick WILKINSON, Manuel Alejandro Sepulveda, Charles George Drake, Derick Siegel
  • Publication number: 20230190903
    Abstract: Disclosed herein are methods of treating or preventing prostate cancer in a subject, the methods comprising administering to the subject a treatment regimen comprising two or more vaccines comprising a great ape adenovirus serotype 20 (GAd20) virus that, in turn, comprises a nucleotide sequence encoding the amino acid sequence of SEQ ID NO: 1 and one or more vaccines comprising a Modified Vaccinia Ankara (MVA) virus that, in turn, comprises a nucleotide sequence encoding the amino acid sequence of SEQ ID NO: 3 to thereby treat or prevent the prostate cancer.
    Type: Application
    Filed: December 13, 2022
    Publication date: June 22, 2023
    Inventors: Patrick WILKINSON, Manuel Alejandro SEPULVEDA, Charles George DRAKE, Derick Siegel
  • Publication number: 20230079750
    Abstract: Described herein are T-cell receptors (TCRs) that bind to CALR or JAK2 antigens. Also described are T-cell receptors (TCRs), polynucleotides, vectors that encode the TCRs, and cells comprising the TCRs, and methods of treatment.
    Type: Application
    Filed: April 4, 2022
    Publication date: March 16, 2023
    Inventors: Rebecca HANSON, Vinod KRISHNA, Manuel Alejandro SEPULVEDA, Patrick WILKINSON
  • Publication number: 20230035403
    Abstract: Disclosed herein are methods of diagnosing and treating a subject with prostate cancer, as well as methods of monitoring the responsiveness of a subject having prostate cancer to a therapeutic agent.
    Type: Application
    Filed: July 2, 2021
    Publication date: February 2, 2023
    Inventors: Denis A. Smirnov, Yashoda Rani Rajpurohit, Vipul Bhargava, Patrick Wilkinson, Kai Fu, Manuel Alejandro Sepulveda
  • Publication number: 20230024133
    Abstract: Disclosed herein are self-replicating RNA molecules encoding prostate neoantigens, vaccines, and method of treating and preventing prostate cancer using the self-replicating RNA molecules and vaccines.
    Type: Application
    Filed: July 2, 2021
    Publication date: January 26, 2023
    Inventors: Jason Lee DeHart, Vipul Bhargava, Patrick Wilkinson, Manuel Alejandro Sepulveda
  • Publication number: 20210222133
    Abstract: Provided are vaccines, polypeptides and polynucleotides based on mutant CALR and JAK2 sequences, vectors, host cells, viruses, and methods of making and using them. The disclosure also provides methods of inducing an immune response and methods of treating, preventing, reducing a risk of onset or delaying the onset of a clinical condition characterized by an expression of JAK2V617F or CALR exon 9 mutant, or both JAK2V617F and CALR exon 9 mutant, wherein the method comprises a plurality of administrations of any of the compositions comprising polynucleotides, polypeptides or vectors disclosed herein.
    Type: Application
    Filed: November 13, 2020
    Publication date: July 22, 2021
    Inventors: Ricardo ATTAR, Jason DEHART, Selina KHAN, Vinod KRISHNA, Jenifer LUM, Christian MAINE, Barbara SANDERS, Manuel Alejandro SEPULVEDA, Patrick WILKINSON, Roland ZAHN
  • Patent number: 9522224
    Abstract: A system includes an inductive backplane, at least one communications interface, and a control unit. The inductive backplane is configured to secure and inductively power a plurality of detachable medical device modules. The control unit controls, via the at least one communications interface, at least one attribute of each medical device module when the medical device module is secured to the inductive backplane. Related apparatus, systems, techniques and articles are also described.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: December 20, 2016
    Assignee: CareFusion 303, Inc.
    Inventors: Gregory Borges, Thomas John Carlisle, Chris Clarke, Pascal Daniel, David George Fern, Timothy Charles Frearson, Igor V. Nesterenko, Stephen Daniel Roberts, Daniel Hans Vik, James Patrick Wilkinson
  • Publication number: 20140276426
    Abstract: A system includes an inductive backplane, at least one communications interface, and a control unit. The inductive backplane is configured to secure and inductively power a plurality of detachable medical device modules. The control unit controls, via the at least one communications interface, at least one attribute of each medical device module when the medical device module is secured to the inductive backplane. Related apparatus, systems, techniques and articles are also described.
    Type: Application
    Filed: March 14, 2013
    Publication date: September 18, 2014
    Applicant: CAREFUSION 303, INC.
    Inventors: Gregory Borges, Thomas John Carlisle, Chris Clarke, Pascal Daniel, David George Fern, Timothy Charles Frearson, Igor V. Nesterenko, Stephen Daniel Roberts, Daniel Hans Vik, James Patrick Wilkinson
  • Patent number: 7854953
    Abstract: A foodstuff supplement and method of producing the foodstuff supplement. The method includes forming a liquid phase and adding vitamins to the liquid phase at a temperature below that at which significant depletion and/or degradation of the vitamins will occur. Oil is heated in a vessel and an emulsifier is added to the heated oil. The resultant mixture is cooled and the liquid phase is added.
    Type: Grant
    Filed: October 18, 2002
    Date of Patent: December 21, 2010
    Assignee: Vita Power Limited
    Inventors: John Richard Palamountain, Ruth Erica Palamountain, Brian Herbert Patrick Wilkinson