Patents by Inventor Patrick Willoughby

Patrick Willoughby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10925998
    Abstract: Aspects herein relate to biocompatible polyisobutylene-fiber composite materials and related methods. In one aspect a biocompatible composite material is included. The biocompatible composite material can include a network of fibers comprising one or more polymers to form a substrate and a continuous, interpenetrating polyisobutylene matrix that is non-porous and completely surrounds the electrospun fibers. Other aspects are included herein.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: February 23, 2021
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Joseph Thomas Delaney, Jr., Patrick Willoughby, David Robert Wulfman, Andrew J. Ro, Niraj Gurung
  • Patent number: 10835638
    Abstract: A block copolymer including a plurality of polymeric chains and a plurality of cross-linking compound residues linking together the plurality of polymeric chains. The plurality of polymeric chains forms a plurality of hard domains and a plurality of soft domains. Each polymeric chain includes a plurality of soft segments and a plurality of hard segments. The plurality of soft segments includes a polyisobutylene diol or diamine residue. The plurality of soft segments forms the plurality of soft domains. The plurality of hard segments including a diisocyanate residue. The plurality of hard segments forms the plurality of hard domains. The cross-linking compound residues link together the hard segments of the plurality of polymeric chains.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: November 17, 2020
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Joseph T. Delaney, Jr., David R. Wulfman, Patrick Willoughby, Andrew J. Ro
  • Patent number: 10526429
    Abstract: A method for making a polyisobutylene diol from a polyisobutylene diallyl. The method includes hydroborating the polyisobutylene diallyl to produce a polyisobutylene dialkyl borane, and oxidizing the polyisobutylene dialkyl borane to form the polyisobutylene diol. The polyisobutylene diallyl is hydroborated by combining in situ the polyisobutylene diallyl with a borane-coordinating solvent, an alkaline metal salt of borohydride, and an acid. The alkaline metal salt of borohydride is combined with the polyisobutylene diallyl before the acid is combined with the polyisobutylene diallyl.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: January 7, 2020
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Joseph T. Delaney, Jr., Andrew J. Ro, Patrick Willoughby, Niraj Gurung
  • Publication number: 20190262131
    Abstract: A prosthetic heart valve leaflet includes a plurality of electrospun fibers at least partially embedded in a polymer matrix. The plurality of fibers includes a first polyisobutylene urethane copolymer having a first predetermined weight average percentage of hard segment portions and the polymer matrix includes a second polyisobutylene urethane copolymer having a second predetermined weight average percentage of the hard segment portions, wherein the first predetermined weight average percentage of the hard segment portions is greater than the second predetermined weight average percentage of the hard segment portions.
    Type: Application
    Filed: May 15, 2019
    Publication date: August 29, 2019
    Inventors: David Robert Wulfman, Thomas A. Wrobel, Crystal Marie Anderson-Cunanan, Joseph Thomas Delaney, JR., Patrick Willoughby, Mark W. Boden, Peter G. Edelman, Michael Eppihimer
  • Publication number: 20190218334
    Abstract: A polymeric material includes a polyisobutylene-polyurethane block copolymer. The polyisobutylene-polyurethane block copolymer includes soft segments, hard segments, and end groups. The soft segments include a polyisobutylene diol residue. The hard segments include a diisocyanate residue. The end groups are bonded by urea bonds to a portion of the diisocyanate residue. The end groups include a residue of a mono-functional amine.
    Type: Application
    Filed: January 15, 2019
    Publication date: July 18, 2019
    Inventors: Joseph T. Delaney, JR., Andrew J. Ro, David R. Wulfman, Niraj Gurung, Patrick Willoughby
  • Patent number: 10314696
    Abstract: A prosthetic heart valve leaflet includes a plurality of electrospun fibers at least partially embedded in a polymer matrix. The plurality of fibers includes a first polyisobutylene urethane copolymer having a first predetermined weight average percentage of hard segment portions and the polymer matrix includes a second polyisobutylene urethane copolymer having a second predetermined weight average percentage of the hard segment portions, wherein the first predetermined weight average percentage of the hard segment portions is greater than the second predetermined weight average percentage of the hard segment portions.
    Type: Grant
    Filed: March 28, 2016
    Date of Patent: June 11, 2019
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: David Robert Wulfman, Thomas A. Wrobel, Crystal Marie Anderson-Cunanan, Joseph Thomas Delaney, Jr., Patrick Willoughby, Mark W. Boden, Peter G. Edelman, Michael Eppihimer
  • Publication number: 20190054204
    Abstract: A block copolymer including a plurality of polymeric chains and a plurality of cross-linking compound residues linking together the plurality of polymeric chains. The plurality of polymeric chains forms a plurality of hard domains and a plurality of soft domains. Each polymeric chain includes a plurality of soft segments and a plurality of hard segments. The plurality of soft segments includes a polyisobutylene diol or diamine residue. The plurality of soft segments forms the plurality of soft domains. The plurality of hard segments including a diisocyanate residue. The plurality of hard segments forms the plurality of hard domains. The cross-linking compound residues link together the hard segments of the plurality of polymeric chains.
    Type: Application
    Filed: August 16, 2018
    Publication date: February 21, 2019
    Inventors: Joseph T. Delaney, JR., David R. Wulfman, Patrick Willoughby, Andrew J. Ro
  • Patent number: 10111986
    Abstract: A method for making a device including a polyisobutylene-polyurethane block copolymer. The method includes polymerizing a polyisobutylene diol, a diisocyanate, and a chain extender within a solvent system to form a polyisobutylene-polyurethane block copolymer solution, depositing the polyisobutylene-polyurethane block copolymer solution onto at least a portion of the device, and evaporating the solvent system from the deposited polyisobutylene-polyurethane block copolymer solution.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: October 30, 2018
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Joseph T. Delaney, Jr., Niraj Gurung, David R. Wulfman, Adegbola O. Adenusi, Patrick Willoughby, Adeniyi O. Aremu
  • Publication number: 20180303972
    Abstract: Aspects herein relate to biocompatible polyisobutylene-fiber composite materials and related methods. In one aspect a biocompatible composite material is included. The biocompatible composite material can include a network of fibers comprising one or more polymers to form a substrate and a continuous, interpenetrating polyisobutylene matrix that is non-porous and completely surrounds the electrospun fibers. Other aspects are included herein.
    Type: Application
    Filed: April 23, 2018
    Publication date: October 25, 2018
    Inventors: Joseph Thomas Delaney, JR., Patrick Willoughby, David Robert Wulfman, Andrew J. Ro, Niraj Gurung
  • Publication number: 20180258196
    Abstract: A method for making a polyisobutylene diol from a polyisobutylene diallyl. The method includes hydroborating the polyisobutylene diallyl to produce a polyisobutylene dialkyl borane, and oxidizing the polyisobutylene dialkyl borane to form the polyisobutylene diol. The polyisobutylene diallyl is hydroborated by combining in situ the polyisobutylene diallyl with a borane-coordinating solvent, an alkaline metal salt of borohydride, and an acid. The alkaline metal salt of borohydride is combined with the polyisobutylene diallyl before the acid is combined with the polyisobutylene diallyl.
    Type: Application
    Filed: March 7, 2018
    Publication date: September 13, 2018
    Inventors: Joseph T. Delaney, JR., Andrew J. Ro, Patrick Willoughby, Niraj Gurung
  • Patent number: 10039918
    Abstract: An implantable lead includes a lead body having a proximal end portion and a distal end portion. The lead body includes an insulative member having a lumen extending longitudinally between the proximal end portion and the distal end portion. The lead body also includes a generally tubular helical liner disposed coaxially with the lumen within the insulative member. A pitch of the helical liner varies along the length of the lead. The implantable lead also includes an electrode disposed along the lead body in the distal end portion thereof, and a conductor disposed within the lumen and electrically coupled to the electrode. A terminal connector is coupled to the proximal end portion of the lead body and to the conductor.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: August 7, 2018
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Arthur J. Foster, Daniel J. Foster, Christopher R. Perrey, Andrew L. De Kock, Patrick Willoughby, Bryan A. Clark
  • Publication number: 20170174845
    Abstract: A polymeric material includes a polyisobutylene-polyurethane block copolymer and a tertiary amine catalyst. The polyisobutylene-polyurethane block copolymer includes soft segments including at least one polyisobutylene diol residue, and hard segments including at least one diisocyanate residue. The polymeric material is free of an organometallic catalyst.
    Type: Application
    Filed: December 16, 2016
    Publication date: June 22, 2017
    Inventors: Joseph T. Delaney, Jr., Niraj Gurung, Patrick Willoughby, David R. Wulfman, Adegbola O. Adenusi, Adeniyi O. Aremu
  • Publication number: 20170106124
    Abstract: A method for making a device including a polyisobutylene-polyurethane block copolymer. The method includes polymerizing a polyisobutylene diol, a diisocyanate, and a chain extender within a solvent system to form a polyisobutylene-polyurethane block copolymer solution, depositing the polyisobutylene-polyurethane block copolymer solution onto at least a portion of the device, and evaporating the solvent system from the deposited polyisobutylene-polyurethane block copolymer solution.
    Type: Application
    Filed: October 14, 2016
    Publication date: April 20, 2017
    Inventors: Joseph T. Delaney, JR., Niraj Gurung, David R. Wulfman, Adegbola O. Adenusi, Patrick Willoughby, Adeniyi O. Aremu
  • Publication number: 20160365692
    Abstract: Various coiled conductors having two or more sections and methods and devices for constructing such conductors are disclosed. The various embodiments of coiled conductors and related methods include two or more sections that can have different mechanical, structural, and/or electrical characteristics.
    Type: Application
    Filed: May 27, 2016
    Publication date: December 15, 2016
    Inventors: Joshua Haarer, Yevgenia Sheikoleslami, Patrick Willoughby, Andrew L. De Kock, Kimberly Ann Miklos, Benjamin J. Haasl, Brian L. Schmidt, Emilio Abner Avilés Delgado, Fabian E. Morales-Ortiz, Ronald W. Kunkel
  • Publication number: 20160296323
    Abstract: A prosthetic heart valve leaflet includes a plurality of electrospun fibers at least partially embedded in a polymer matrix. The plurality of fibers includes a first polyisobutylene urethane copolymer having a first predetermined weight average percentage of hard segment portions and the polymer matrix includes a second polyisobutylene urethane copolymer having a second predetermined weight average percentage of the hard segment portions, wherein the first predetermined weight average percentage of the hard segment portions is greater than the second predetermined weight average percentage of the hard segment portions.
    Type: Application
    Filed: March 28, 2016
    Publication date: October 13, 2016
    Inventors: David Robert Wulfman, Thomas A. Wrobel, Crystal Marie Anderson-Cunanan, Joseph Thomas Delaney, JR., Patrick Willoughby, Mark W. Boden, Peter G. Edelman, Michael Eppihimer
  • Publication number: 20160235966
    Abstract: An implantable lead includes a lead body having a proximal end portion and a distal end portion. The lead body includes an insulative member having a lumen extending longitudinally between the proximal end portion and the distal end portion. The lead body also includes a generally tubular helical liner disposed coaxially with the lumen within the insulative member. A pitch of the helical liner varies along the length of the lead. The implantable lead also includes an electrode disposed along the lead body in the distal end portion thereof, and a conductor disposed within the lumen and electrically coupled to the electrode. A terminal connector is coupled to the proximal end portion of the lead body and to the conductor.
    Type: Application
    Filed: April 25, 2016
    Publication date: August 18, 2016
    Inventors: Arthur J. Foster, Daniel J. Foster, Christopher R. Perrey, Andrew L. De Kock, Patrick Willoughby, Bryan A. Clark
  • Patent number: 9379508
    Abstract: Various coiled conductors having two or more sections and methods and devices for constructing such conductors are disclosed. The various embodiments of coiled conductors and related methods include two or more sections that can have different mechanical, structural, and/or electrical characteristics.
    Type: Grant
    Filed: July 17, 2013
    Date of Patent: June 28, 2016
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Joshua Haarer, Yevgenia Sheikholeslami, Patrick Willoughby, Andrew L. De Kock, Kimberly A. Morris, Benjamin J. Haasl, Brian L. Schmidt, Emilio Abner Avilés Delgado, Fabian E. Morales-Ortiz, Ronald W. Kunkel
  • Patent number: 9364662
    Abstract: An implantable lead includes a lead body having a proximal end portion and a distal end portion. The lead body includes an insulative member having a lumen extending longitudinally between the proximal end portion and the distal end portion. The lead body also includes a generally tubular liner disposed coaxially with the lumen within the insulative member. The implantable lead also includes an electrode disposed along the lead body in the distal end portion thereof, and a conductor disposed within the lumen and electrically coupled to the electrode. A terminal connector is coupled to the proximal end portion of the lead body and to the conductor.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: June 14, 2016
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Arthur J. Foster, Daniel J. Foster, Christopher R. Perrey, Andrew L. De Kock, Patrick Willoughby, Bryan A. Clark
  • Patent number: 8983622
    Abstract: Medical lead body configurations that reduce conductor flexural fatigue. The various lead body embodiments include a support section and can also include other features such as a semi-straight portion of a lumen or semi-straight sides that optimize the reduction in conductor flexural fatigue.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: March 17, 2015
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Ronald W. Kunkel, Andrew De Kock, Steven B. Rasmussen, Patrick Willoughby
  • Publication number: 20140135885
    Abstract: An implantable lead includes a lead body having a proximal end portion and a distal end portion. The lead body includes an insulative member having a lumen extending longitudinally between the proximal end portion and the distal end portion. The lead body also includes a generally tubular liner disposed coaxially with the lumen within the insulative member. The implantable lead also includes an electrode disposed along the lead body in the distal end portion thereof, and a conductor disposed within the lumen and electrically coupled to the electrode. A terminal connector is coupled to the proximal end portion of the lead body and to the conductor.
    Type: Application
    Filed: November 8, 2013
    Publication date: May 15, 2014
    Applicant: Cardiac Pacemakers, Inc.
    Inventors: Arthur J. Foster, Daniel J. Foster, Christopher R. Perrey, Andrew L. De Kock, Patrick Willoughby, Bryan A. Clark