Patents by Inventor Patrik Hosek

Patrik Hosek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Milling process for the production of finely milled medicinal substances
    Publication number: 20060002864
    Abstract: The present invention is a method of milling materials to form a fine powder with a median particle size below 10 micrometer which is suitable for inhalation and which has substantially no amorphous content generated during milling. The method is particularly suitable for milling materials which are soft. The method comprises milling the material in a fluid energy mill at reduced temperature using helium, or helium mixed with another gas, as milling fluid. Temperatures of ?30° C. or less are used.
    Type: Application
    Filed: September 7, 2005
    Publication date: January 5, 2006
    Applicant: Aventis Pharma Limited
    Inventors: Jean-Rene Authelin, Patrik Hosek
  • Milling process for the production of finely milled medicinal substances
    Patent number: 6641063
    Abstract: The invention is an improved method of generating fine medicament powders suitable for inhalation. A fluid energy mill is used with conventional milling fluids such as air or nitrogen. The milling fluid is treated to have a controlled relative humidity of between 30% and 70%. This produces a fine medicament powder with a median particle size below 10 micrometer but with little or no amorphous content generated during milling. Scale formation in the mill chamber is also greatly reduced.
    Type: Grant
    Filed: June 1, 2001
    Date of Patent: November 4, 2003
    Assignee: Aventis Pharma Limited
    Inventors: Narasimha M. Vemuri, Andrew B. Brown, Jean-Rene Authelin, Patrik Hosek
  • Milling process for the production of finely milled medicinal substances
    Publication number: 20020114766
    Abstract: The present invention is a method of milling materials to form a fine powder with a median particle size below 10 micrometer which is suitable for inhalation and which has substantially no amorphous content generated during milling. The method is particularly suitable for milling materials which are soft. The method comprises milling the material in a fluid energy mill at reduced temperature using helium, or helium mixed with another gas, as milling fluid. Temperatures of −30° C. or less are used.
    Type: Application
    Filed: June 1, 2001
    Publication date: August 22, 2002
    Inventors: Jean-Rene Authelin, Patrik Hosek
  • Milling process for the production of finely milled medicinal substances
    Publication number: 20020109025
    Abstract: The invention is an improved method of generating fine medicament powders suitable for inhalation. A fluid energy mill is used with conventional milling fluids such as air or nitrogen. The milling fluid is treated to have a controlled relative humidity of between 30% and 70%. This produces a fine medicament powder with a median particle size below 10 micrometer but with little or no amorphous content generated during milling. Scale formation in the mill chamber is also greatly reduced.
    Type: Application
    Filed: June 1, 2001
    Publication date: August 15, 2002
    Inventors: Narasimha M. Vemuri, Andrew B. Brown, Jean-Rene Authelin, Patrik Hosek