Patents by Inventor Patrizia Boniforte

Patrizia Boniforte has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210085611
    Abstract: A pharmaceutical formulation has (S)-[2-chloro-4-fluoro-5-(7-tnorpholin-4-yl-quinazolin-4-yl)phenyl]-(6-methoxy-pyridazin-3-yl)methanol or pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 28, 2018
    Publication date: March 25, 2021
    Applicant: Merck Patent GmbH
    Inventors: Simon GEISSLER, Martina Jeschke, Patrizia Boniforte, Markus Weigandt
  • Publication number: 20160279213
    Abstract: The invention relates to a therapeutically effective truncated survivin and its therapeutic use as vaccine in a liposomal preparation, wherein the survivin fragment is preferably gluconoylated, and said liposomal preparation elicits in-vivo anti-tumor activity. The invention is directed, in more detail, to a cancer vaccine comprising a fragment of human survivin that is specifically effective in conjunction with an lipid adjuvant. The invention relates in more detail to a liposomal vaccine delivery system comprising an active truncated survivin molecule as tumor antigen and a chiral cationic lipid, for example R-DOTAP acting as adjuvant, which is part of the liposome preparation, wherein the liposomal drug delivery system is optimized with regard to its lipid and adjuvant components, physical or physicochemical parameters, and the final therapeutic efficacy of the released truncated survivin molecules.
    Type: Application
    Filed: December 16, 2014
    Publication date: September 29, 2016
    Inventors: Simon Geissler, Patrizia Boniforte, Joerg Plaschke, Markus Weigandt, Stefan Jaekel, Roland Kellner, Thomas Rysiok, Dirk Mueller-Pompalla, Kenneth Hance