Patents by Inventor Patrizia Caldirola

Patrizia Caldirola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED QUINOLINES FOR USE AS VEGF INHIBITORS
    Publication number: 20120065199
    Abstract: A compound of formula (I) as well as pharmaceutically acceptable salts thereof and pharmaceutical compositions including a therapeutically effective amount of the compounds. The compound is useful in treatment of cancer, diabetic retinopathy, age-related macular degeneration, inflammation, stroke, ischemic myocardium, atherosclerosis, macular edema and psoriasis.
    Type: Application
    Filed: May 20, 2010
    Publication date: March 15, 2012
    Applicant: CLANOTECH AB
    Inventors: Johan Malm, Rune Ringom, Patrizia Caldirola, Jacob Westman
  • New Compounds
    Publication number: 20100222330
    Abstract: The present invention relates to substituted sulfonamide compounds of the general formula (I), wherein P is sulfonamide or amide-substituted sulfonic acid, which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
    Type: Application
    Filed: May 17, 2010
    Publication date: September 2, 2010
    Applicant: BIOVITRUM AB
    Inventors: Patrizia Caldirola, Gary Johansson, Andrew Mott, Katarina Beierlein, Markus Thor, Lars Tedenborg, Ulf Bremberg, Annika Jenmalm Jensen
  • Aryl sulfonamide compounds for treating obesity
    Patent number: 7718650
    Abstract: The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: May 18, 2010
    Assignee: Biovitrum AB
    Inventors: Ulf Bremberg, Patrizia Caldirola, Annika J. Jensen, Gary Johansson, Lori Sutin, Andrew Mott, Jan Tejbrant
  • Substituted sulphonamide compound and uses thereof
    Patent number: 7582767
    Abstract: The present invention relates to compounds of the formula (I), wherein R1 and R2 are as defined in the description; to pharmaceutical formulations comprising these compounds, and to the use of the compounds for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes, and/or CNS disorders, to achieve reduction of body weight and/or body weight gain.
    Type: Grant
    Filed: June 5, 2006
    Date of Patent: September 1, 2009
    Assignee: Biovitrum AB (publ.)
    Inventors: Patrizia Caldirola, Gary Johansson, Lori Sutin
  • Substituted naphthalene sulfonamides
    Patent number: 7572787
    Abstract: The present invention relates to substituted sulfonamide compounds of the general formula (I), wherein P is sulfonamide or amide-substituted sulfonic acid, which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
    Type: Grant
    Filed: August 25, 2006
    Date of Patent: August 11, 2009
    Assignee: Biovitrum AB
    Inventors: Patrizia Caldirola, Ulf Bremberg, Gary Johansson, Andrew Mott, Annika Jenmalm Jensen, Katarina Beierlien, Markus Thor, Lars Tedenborg
  • Substituted sulfonamide compounds useful for the prophylaxis and treatment of conditions relating to obesity, type II diabetes and/or disorders of the central nervous system
    Patent number: 7566715
    Abstract: The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
    Type: Grant
    Filed: August 30, 2005
    Date of Patent: July 28, 2009
    Assignee: Biovitrum AB
    Inventors: Ulf Bremberg, Patrizia Caldirola, Annika J. Jensen, Gary Johansson, Lori Sutin, Andrew Mott, Jan Tejbrant
  • Compounds, their use and preparation
    Patent number: 7524839
    Abstract: The invention-provides 2, 3-, 4- or 5-substituted-N1-(arylsulfonyl)indole and (heteroaryl)indole compounds of the general formula (I): in which Ar, R2, R3, R4 and R5 are as defined in the specification. The compounds bind to the 5-HT6 receptor and are useful for the treatment and prophylaxis of disorders mediated by the 5-HT6 receptor, such as obesity and CNS disorders.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: April 28, 2009
    Inventors: Patrizia Caldirola, Björn M. Nilsson, Gary Johansson
  • NEW COMPOUNDS
    Publication number: 20080096873
    Abstract: The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
    Type: Application
    Filed: December 19, 2007
    Publication date: April 24, 2008
    Inventors: Ulf Bremberg, Patrizia Caldirola, Annika Jensen, Gary Johansson, Lori Sutin, Andrew Mott, Jan Tejbrant
  • Compounds
    Patent number: 7319097
    Abstract: The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system
    Type: Grant
    Filed: August 30, 2005
    Date of Patent: January 15, 2008
    Assignee: Biovitrum AB
    Inventors: Ulf Bremberg, Patrizia Caldirola, Annika J. Jensen, Gary Johansson, Lori Sutin, Andrew Mott, Jan Tejbrant
  • Compounds
    Publication number: 20070066600
    Abstract: The present invention relates to substituted sulfonamide compounds of the general formula (I), wherein P is sulfonamide or amide-substituted sulfonic acid, which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
    Type: Application
    Filed: August 25, 2006
    Publication date: March 22, 2007
    Inventors: Patrizia Caldirola, Ulf Bremberg, Gary Johansson, Andrew Mott, Annika Jensen, Katarina Beierlien, Markus Thor, Lars Tedenborg
  • Arylsulfonamide compounds
    Patent number: 7173035
    Abstract: The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
    Type: Grant
    Filed: May 10, 2002
    Date of Patent: February 6, 2007
    Assignee: Biovitrum AB
    Inventors: Ulf Bremberg, Patrizia Caldirola, Annika J. Jensen, Gary Johansson, Lori Sutin, Andrew Mott, Jan Tejbrant
  • Compounds
    Publication number: 20060293361
    Abstract: The present invention relates to compounds of the formula (I), wherein R1 and R2 are as defined in the description; to pharmaceutical formulations comprising these compounds, and to the use of the compounds for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes, and/or CNS disorders, to achieve reduction of body weight and/or body weight gain.
    Type: Application
    Filed: June 5, 2006
    Publication date: December 28, 2006
    Inventors: Patrizia Caldirola, Gary Johansson, Lori Sutin
  • Bicyclic sulfonamide compounds
    Patent number: 7144883
    Abstract: The present invention relates to substituted sulfonamide compounds of the general formula (I), wherein P is sulfonamide or amide-substituted sulfonic acid, which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system
    Type: Grant
    Filed: June 11, 2002
    Date of Patent: December 5, 2006
    Assignee: Biovitrum AB
    Inventors: Patrizia Caldirola, Gary Johansson, Andrew Mott, Katarina Beierlien, Markus Thor, Lars Tedenborg, Ulf Bremberg, Annika Jenmalm Jensen
  • Compounds, their use and preparation
    Patent number: 7087750
    Abstract: The invention provides 2, 3-, 4- or 5-substituted-N1-(arylsulfonyl)indole and (heteroaryl)indole compounds of the general formula (I): in which Ar, R2, R3, R4 and R5 are as defined in the specification. The compounds bind to the 5-HT6 receptor and are useful for the treatment and prophylaxis of disorders mediated by the 5-HT6 receptor, such as obesity and CNS disorders.
    Type: Grant
    Filed: October 22, 2001
    Date of Patent: August 8, 2006
    Assignee: Biovitrum AB
    Inventors: Patrizia Caldirola, Björn M. Nilsson, Gary Johansson
  • New compounds
    Publication number: 20060009446
    Abstract: The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
    Type: Application
    Filed: August 30, 2005
    Publication date: January 12, 2006
    Inventors: Ulf Bremberg, Patrizia Caldirola, Annika Jensen, Gary Johansson, Lori Sutin, Andrew Mott, Jan Tejbrant
  • New compounds
    Publication number: 20050288275
    Abstract: The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
    Type: Application
    Filed: August 30, 2005
    Publication date: December 29, 2005
    Inventors: Ulf Bremberg, Patrizia Caldirola, Annika Jensen, Gary Johansson, Lori Sutin, Andrew Mott, Jan Tejbrant
  • Compounds
    Patent number: 6969710
    Abstract: The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
    Type: Grant
    Filed: May 13, 2002
    Date of Patent: November 29, 2005
    Assignee: Biovitrum AB
    Inventors: Ulf Bremberg, Patrizia Caldirola, Annika J. Jensen, Gary Johansson, Andrew Mott, Lori Sutin, Jan Tejbrant
  • Novel compounds, their use and preparation
    Publication number: 20050256106
    Abstract: The invention-provides 2, 3-, 4- or 5-substituted-N1-(arylsulfonyl)indole and (heteroaryl)indole compounds of the general formula (I): in which Ar, R2, R3, R4 and R5 are as defined in the specification. The compounds bind to the 5-HT6 receptor and are useful for the treatment and prophylaxis of disorders mediated by the 5-HT6 receptor, such as obesity and CNS disorders.
    Type: Application
    Filed: February 11, 2005
    Publication date: November 17, 2005
    Inventors: Patrizia Caldirola, Bjorn Nilsson, Gary Johansson
  • Use
    Publication number: 20030166663
    Abstract: The invention provides methods of treatment or prophylaxis of obesity, or methods of treatment for the reduction of food intake, comprising administering to a patient in need of such treatment a therapeutically effective amount of a sulfonamide compound of Formula I: 1
    Type: Application
    Filed: November 8, 2002
    Publication date: September 4, 2003
    Inventor: Patrizia Caldirola
  • New compounds
    Publication number: 20030158202
    Abstract: The present invention relates to substituted sulfonamide compounds of the general formula (I), wherein P is sulfonamide or amide-substituted sulfonic acid, which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
    Type: Application
    Filed: June 11, 2002
    Publication date: August 21, 2003
    Inventors: Patrizia Caldirola, Gary Johansson, Andrew Mott, Katarina Beierlien, Markus Thor, Lars Tedenborg, Ulf Bremberg, Annika Jenmalm Jensen