Patents by Inventor Paul A. Clark

Paul A. Clark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240018263
    Abstract: The present invention provides antibodies that target glioblastoma stem-like cells and methods and kits for their use.
    Type: Application
    Filed: September 7, 2023
    Publication date: January 18, 2024
    Inventors: Michael Zorniak, Paul A. Clark, Yongku Peter Cho, Benjamin J. Umlauf, Eric V. Shusta, John Shu-Shin Kuo
  • Patent number: 11780932
    Abstract: The present invention provides antibodies that target glioblastoma stem-like cells and methods and kits for their use.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: October 10, 2023
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Michael Zorniak, Paul A. Clark, Yongku Peter Cho, Benjamin J. Umlauf, Eric V. Shusta, John Shu-Shin Kuo
  • Publication number: 20200354472
    Abstract: The present invention provides antibodies that target glioblastoma stem-like cells and methods and kits for their use.
    Type: Application
    Filed: October 9, 2018
    Publication date: November 12, 2020
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Michael Zorniak, Paul A. Clark, Yongku Peter Cho, Benjamin J. Umlauf, Eric V. Shusta, John Shu-Shin Kuo
  • Patent number: 10610611
    Abstract: A water-based fragrance composition comprises at least about 67 wt % water and between about 5 and about 17 wt % of a first organic solvent, wherein the first organic solvent comprises one or more relatively volatile, water soluble, low molecular weight organic compound(s) having a boiling point less than about 100° C. The water-based fragrance composition further comprises about 5 wt % or less of at least one fragrance formulation and between about 0 and about 22 wt % of a second organic solvent, wherein the second organic solvent comprises one or more moderately volatile, water soluble organic compound(s) having a boiling point greater than or equal to about 100° C. and less than or equal to about 300° C.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: April 7, 2020
    Assignee: S. C. Johnson & Son, Inc.
    Inventors: Rachel E. Salowitz, Paul A. Clark
  • Patent number: 10427862
    Abstract: An aerosol dispenser assembly is disclosed that includes a container holding a liquid product and a compressed gas propellant for propelling the liquid product from the container. A design methodology for the actuator body and swirl nozzle insert is disclosed for maintaining a small particle size or Sauter Mean Diameter (D[3, 2]) of less than 48 ?m at a suitable spray rate (1.5-2 g/s), while utilizing a compressed gas VOC-free propellant for an air freshener product. As obtaining reduced particle size to compete with LPG propellants may result in a reduced spray rate, it is anticipated that one or more nozzles may be designed into the actuator body to maintain a suitable spray rate.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: October 1, 2019
    Assignee: S.C. JOHNSON & SON, INC.
    Inventors: Paul A. Clark, Richard S. Valpey, III, Padma Prabodh Varanasi, Jeffrey J. Christianson, Nitin Sharma, Milind A. Jog
  • Publication number: 20180207309
    Abstract: A water-based fragrance composition comprises at least about 67 wt % water and between about 5 and about 17 wt % of a first organic solvent, wherein the first organic solvent comprises one or more relatively volatile, water soluble, low molecular weight organic compound(s) having a boiling point less than about 100° C. The water-based fragrance composition further comprises about 5 wt % or less of at least one fragrance formulation and between about 0 and about 22 wt % of a second organic solvent, wherein the second organic solvent comprises one or more moderately volatile, water soluble organic compound(s) having a boiling point greater than or equal to about 100° C. and less than or equal to about 300° C.
    Type: Application
    Filed: July 19, 2016
    Publication date: July 26, 2018
    Applicant: S. C. JOHNSON & SON, INC.
    Inventors: Rachel E. SALOWITZ, Paul A. CLARK
  • Publication number: 20160264344
    Abstract: Pressurized compositions propelled by a pressurizing component (preferably a propellant such as compressed gas) and further including at least one active ingredient, at least one high molecular weight nonionic surfactant, and water which is a major component of the composition and is at least substantially ion-free and/or salt-free (preferably ion-free and salt-free), wherein the composition is stored in and dispensed from a plastic pressurized container. The plastic is preferably PET or PEN. The composition has a pH of about 4 to about 8.5. The composition can include as active ingredient(s), one or more of a fragrance component, an odor eliminating compound, an insecticide, an antimicrobial, and a disinfectant.
    Type: Application
    Filed: April 8, 2016
    Publication date: September 15, 2016
    Applicant: S. C. Johnson & Son, Inc.
    Inventors: Paul A. Clark, Kimberly J. Harris, Peter N. Nguyen, Rachel E. Salowitz, Bhaveshkumar Shah, Maciej K. Tasz, John S. Trent
  • Patent number: 9364007
    Abstract: A composition for solvating one or more active agents in an aqueous solution which is suitable for dispensing as a compressed gas aerosol composition is disclosed. The composition includes at least one surfactant, at least one active agent (such as a fragrance or an insecticide), and a compressed gas propellant. The at least one surfactant is preferably present in an amount from about 0.1 wt. % to about 3 wt. %. The at least one active agent is preferably present in an amount from about 0.1 wt. % to about 2 wt. %. The compressed gas propellant is preferably present in an amount from about 0.1 wt. % to about 1 wt. %. The total surfactant weight to active agent weight ratio for the composition is preferably about 1:3 to 5:1. The composition uses a reduced amount of surfactant and active agent thereby allowing for a more efficient active agent loading and a reduced stickiness or tackiness on surfaces contacted during use.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: June 14, 2016
    Assignee: S. C. Johnson & Sons, Inc.
    Inventors: Paul A. Clark, Richard S. Valpey, III, Maciej K. Tasz
  • Publication number: 20160068331
    Abstract: An aerosol dispenser assembly is disclosed that includes a container holding a liquid product and a compressed gas propellant for propelling the liquid product from the container. A design methodology for the actuator body and swirl nozzle insert is disclosed for maintaining a small particle size or Sauter Mean Diameter (D[3, 2]) of less than 48 ?m at a suitable spray rate (1.5-2 g/s), while utilizing a compressed gas VOC-free propellant for an air freshener product. As obtaining reduced particle size to compete with LPG propellants may result in a reduced spray rate, it is anticipated that one or more nozzles may be designed into the actuator body to maintain a suitable spray rate.
    Type: Application
    Filed: November 19, 2015
    Publication date: March 10, 2016
    Applicant: S.C. JOHNSON & SON, INC.
    Inventors: Paul A. Clark, Richard S. Valpey, III, Prabodh Varanasi, Jeffrey J. Christianson, Nitin Sharma, Milind A. Jog
  • Patent number: 9242256
    Abstract: An aerosol dispenser assembly is disclosed that includes a container holding a liquid product and a compressed gas propellant for propelling the liquid product from the container. A design methodology for the actuator body and swirl nozzle insert is disclosed for maintaining a small particle size or Sauter Mean Diameter (D[3, 2]) of less than 48 ?m at a suitable spray rate (1.5-2 g/s), while utilizing a compressed gas VOC-free propellant for an air freshener product. As obtaining reduced particle size to compete with LPG propellants may result in a reduced spray rate, it is anticipated that one or more nozzles may be designed into the actuator body to maintain a suitable spray rate.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: January 26, 2016
    Assignee: S.C. Johnson & Son, Inc.
    Inventors: Paul A. Clark, Richard S. Valpey, III, Prabodh Padma Varanasi, Jeffrey J. Christianson, Nitin Sharma, Milind A. Jog
  • Publication number: 20150181891
    Abstract: A composition for solvating one or more active agents in an aqueous solution which is suitable for dispensing as a compressed gas aerosol composition is disclosed. The composition includes at least one surfactant, at least one active agent (such as a fragrance or an insecticide), and a compressed gas propellant. The at least one surfactant is preferably present in an amount from about 0.1 wt. % to about 3 wt. %. The at least one active agent is preferably present in an amount from about 0.1 wt. % to about 2 wt. %. The compressed gas propellant is preferably present in an amount from about 0.1 wt. % to about 1 wt. %. The total surfactant weight to active agent weight ratio for the composition is preferably about 1:3 to 5:1. The composition uses a reduced amount of surfactant and active agent thereby allowing for a more efficient active agent loading and a reduced stickiness or tackiness on surfaces contacted during use.
    Type: Application
    Filed: March 12, 2015
    Publication date: July 2, 2015
    Applicant: S. C. JOHNSON & SON, INC.
    Inventors: Paul A. Clark, Richard S. Valpey, III, Maciej K. Tasz
  • Patent number: 9056962
    Abstract: A protective sealant composition that is useful for sealing a colorant to a substrate, such as carpet. The protective sealant composition is formulated such that, upon drying, the composition forms a topcoat on the surface of the substrate, with the topcoat having a hard component and a soft component. The composition provides a durable protection against color fading and resoiling to the applied colorant, as well as to the rest of the surface of the substrate. The composition also provides wear resistance to the carpet by reducing the amount that the widths of the top ends of carpet fibers increase when subjected to wearing.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: June 16, 2015
    Assignee: S.C. Johnson & Son, Inc.
    Inventors: Paul A. Clark, Holly Ann St. Martin
  • Patent number: 9044414
    Abstract: A composition for solvating one or more active agents in an aqueous solution which is suitable for dispensing as a compressed gas aerosol composition is disclosed. The composition includes at least one surfactant, at least one active agent, and a compressed gas propellant. The at least one surfactant is preferably present in an amount from about 0.1 wt. % to about 3 wt. %. The at least one active agent is preferably present in an amount from about 0.1 wt. % to about 2 wt. %. The compressed gas propellant is preferably present in an amount from about 0.1 wt. % to about 1 wt. %. The total surfactant weight to active agent weight ratio for the composition is preferably about 1:3 to 5:1. The composition uses a reduced amount of surfactant and active agent thereby allowing for a more efficient active agent loading and a reduced stickiness or tackiness on surfaces contacted during use.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: June 2, 2015
    Assignee: S.C. Johnson & Son, Inc.
    Inventors: Paul A. Clark, Richard S. Valpey, III, Maciej K. Tasz
  • Patent number: 9040024
    Abstract: An air treating composition for eliminating airborne malodors and/or sanitizing air in combination with a spray valve and actuator and spray performance parameters providing maximum dispersion of the composition is disclosed. The particles of the composition are small so that the active component is dispersed into air as a fine dispersion to provide more contact with malodors and to provide quick absorption of malodors and/or bacteria. The particle size of the composition is controlled through the valve and actuator dimensions, as well as the formulation requirements of the composition. The air treating composition includes water, a low molecular weight polyol, and a propellant. The composition may also include one or more adjuvants such as an emulsifier, a co-solvent, a fragrance, a corrosion inhibitor, a pH adjusting agent and the like.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: May 26, 2015
    Assignee: S.C. Johnson & Son, Inc.
    Inventors: Maciej K. Tasz, Richard S. Valpey, III, Paul A. Clark
  • Publication number: 20150044362
    Abstract: A method of sealing a colorant to carpet. The colorant is applied to the carpet. A composition that coalesces and causes the colorant to flow onto fibers of the carpet is applied. The colorant and the composition are dried. The composition is formulated to form a topcoat on the carpet, such that upon drying the topcoat has a hard component and a soft component.
    Type: Application
    Filed: October 23, 2014
    Publication date: February 12, 2015
    Applicant: S.C. JOHNSON & SON, INC.
    Inventors: Paul A. Clark, Holly Ann St. Martin
  • Publication number: 20150045473
    Abstract: A composition includes a first solvent, a second solvent, a first surfactant for maintaining a dispersion of at least one of the first solvent and the second solvent, a first film forming polyurethane dispersion, a second film forming polyurethane dispersion, and a second surfactant for maintaining at least one of the first film forming polyurethane dispersion and the second film forming polyurethane dispersion.
    Type: Application
    Filed: October 23, 2014
    Publication date: February 12, 2015
    Applicant: S.C. Johnson & Son, Inc.
    Inventors: Paul A. Clark, Holly Ann St. Martin
  • Patent number: 8865132
    Abstract: Certain surfactants suitable for use alone to dissolve a water-insoluble component in compositions is described for providing VOC-free compressed gas aerosol compositions. The compositions include water-insoluble component(s), a surfactant and water. The water-insoluble component(s) can be active agent(s), such as fragrance(s) and/or an insecticide(s). The surfactant is present as a single surfactant which, in the absence of a solvent, dissolves or disperses the water-insoluble component(s) and provides a homogenous blend in water which provides a stable compressed gas emulsion.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: October 21, 2014
    Assignee: S.C. Johnson & Son, Inc.
    Inventors: Richard S. Valpey, III, Paul A. Clark, Jessica A. Elwell (nee Heiser)
  • Publication number: 20140303307
    Abstract: A composition for treating a surface such as carpets. The composition includes a film forming polyurethane dispersion having first and second film forming polyurethane dispersions. The film forming polyurethane dispersion forms a film when applied to a surface such as a polyester fiber carpet, and the film, upon drying, forms a topcoat on the surface (e.g., the polyester fiber carpet). The first film forming polyurethane dispersion forms a hard component of the topcoat, and the second film forming polyurethane dispersion forms a soft component of the topcoat. The composition also has a solvent that coalesces particles of a surface colorant and causes the particles to flow into the surface, such as carpet fibers, when the composition is applied to the surface. The composition seals and protects a portion of the surface, such as polyester fiber carpet, to which the colorant is applied.
    Type: Application
    Filed: June 20, 2014
    Publication date: October 9, 2014
    Applicant: S.C. JOHNSON & SON, INC.
    Inventors: Paul A. Clark, Holly Ann St. Martin, Cary E. Manderfield
  • Publication number: 20140303276
    Abstract: A composition for sealing a colorant that is applied to a surface, such as carpets. The composition includes a film forming polyurethane dispersion having first and second film forming polyurethane dispersions. The film forming polyurethane dispersion forms a film when applied to the surface, such as a polyester carpet, and the film, upon drying, forms a topcoat on the surface. The first film forming polyurethane dispersion forms a hard component of the topcoat, and the second film forming polyurethane dispersion forms a soft component of the topcoat. The composition also has a solvent that coalesces particles of a surface colorant and causes the particles to flow into the surface, such as carpet fibers, when the composition is applied to the surface. When the composition is dried on a portion of the surface, to which the colorant is applied, the composition seals and protects that portion of the surface.
    Type: Application
    Filed: June 20, 2014
    Publication date: October 9, 2014
    Applicant: S.C. JOHNSON & SON, INC.
    Inventors: Paul A. Clark, Holly Ann St. Martin, Cary E. Manderfield
  • Patent number: 8846154
    Abstract: Compositions, methods, apparatuses, kits, and combinations are described for permanently or temporarily re-designing, decorating, and/or re-coloring a surface. The compositions useful in the present disclosure include a décor product formulated to be applied and affixed to a surface. If desired, the décor product may be substantially removed from the surface before being affixed thereto. If a user desires to remove the décor product, the décor product may be removed by, for example, vacuuming, wet extraction, chemical application, and the like. If the user desires to affix the décor product to the surface in a permanent or semi-permanent manner, the décor product may be affixed by applying energy thereto in the form of, for example, heat, pressure, emitted waves, an emitted electrical field, a magnetic field, and/or a chemical. The décor product may also be part of a kit or in conjunction with a design device, such as a stencil, to control the application of the décor product to a surface.
    Type: Grant
    Filed: May 6, 2011
    Date of Patent: September 30, 2014
    Assignee: S.C. Johnson & Son, Inc.
    Inventors: Paul A. Clark, James F. Kimball, Ketan N. Shah, Therese A. Rozek, Benjamin A. Bass, Robert Y. Lochhead