Abstract: Aspects of the invention described herein include a hydrogel prodrug and methods of making a hydrogel prodrug for drug delivery. Also contemplated are methods of treating, inhibiting, ameliorating or inhibiting a disease or disorder. Without being limiting, the methods for treatment can be directed to a cancer, HIV, a virus, pain, a bacterial infection, a neurological disorder, hemorrhaging, multiple sclerosis, diabetes, high blood pressure, Alzheimer's, or inhibiting a fungal growth in a subject in need.

Abstract: Systems, apparatuses, methods, and computer program products are disclosed for predicting an emotion based on speech and text derived from the speech. An example method includes capturing speech and generating hidden vectors based on the speech and text derived from the speech. The example method further includes generating a word aligned hidden vector based on the speech hidden vector and text hidden vector. The example method further includes generating a hidden vector based on the word aligned hidden vector and the text hidden vector. The example method further includes, after further processing of the final vector, generating one or more probabilities corresponding to one or more emotions. The example method finally includes determining a next action based on the generated one or more probabilities corresponding to one or more emotions.

Abstract: Method for detecting a urinary tract infection (UTI) in a subject comprising determining levels of one or more biomarkers selected from MMP8, HNE, Cystatin C, MMP9, HSA, IL-8, interleukin-6 (IL-6), interleukin-1 beta (IL-1b), fibrinogen, RBP4, active MMP9 and MMP2, NGAL, Desmosine, MPO and CRP in a urine sample obtained from the subject. The determined levels may then be compared with a threshold level, wherein increased levels of at least one of the biomarkers in the urine sample relative to the threshold level is indicative of the presence of a urinary tract infection. Methods for monitoring a UTI and monitoring treatment of a UTI are also provided as are companion systems or test kits.

Abstract: An electronic assembly may include a component comprising conductive studs disposed over an active layer of the component. A first encapsulant layer may be disposed around four side surfaces of the component, over the active layer of the component, and contacting at least a portion of the sides of the conductive studs. A substantially planar surface may be disposed over the active layer of the component, wherein the substantially planar surface comprises ends of the conductive studs and the first encapsulant layer. The first encapsulant layer comprises a roughness less than 500 nanometers. First conductive elements may be disposed over the encapsulant and coupled with the conductive studs. A second layer of encapsulant may be disposed over the first conductive elements.

Abstract: The disclosed technology relates to redox flow batteries (“RFB”), and particularly to electrolytes useful in RFBs based on 2,5-dimercapto-1,3,4-thiadiazole (“DMTD”) and derivatives thereof.

Abstract: Aspects of the invention described herein include a hydrogel prodrug and methods of making a hydrogel prodrug for drug delivery. Also contemplated are methods of treating, inhibiting, ameliorating or inhibiting a disease or disorder. Without being limiting, the methods for treatment can be directed to a cancer, HIV, a virus, pain, a bacterial infection, a neurological disorder, hemorrhaging, multiple sclerosis, diabetes, high blood pressure, Alzheimer's, or inhibiting a fungal growth in a subject in need.

Abstract: A trim attachment system includes a light fixture housing and a first coiled spring bracket having a first coil section and a first elongated section. The first elongated section is positioned in the light fixture housing and attached to the light fixture housing, where the first coil section is attachable to a trim to pull up the trim toward an opening of the housing. The trim attachment system further includes a second coiled spring bracket having a second coil section and a second elongated section. The second elongated section is positioned in the light fixture housing and attached to the light fixture housing, where the second coil section is attachable to the trim to pull up the trim toward the opening of the housing.

Abstract: Methods for monitoring inflammation status of a subject comprise determining levels of at least one neutrophil activation marker, or at least three markers, in urine samples taken from the subject at multiple time points, wherein increased levels of the at least one neutrophil activation marker, or at least one of the markers, in a urine sample are indicative of or predictive of an exacerbation of inflammation and/or wherein decreased levels of the at least one neutrophil activation marker, or at least one of the markers, in a urine sample following an increase are indicative or predictive of recovery from, or successful treatment of, an exacerbation of inflammation. Corresponding systems, test kits and computer programs are provided.

Abstract: A housing of a device comprises a screw boss that extends outwardly from a first base plate proximate to a corner of the housing. Additionally, the housing of the device includes a force dissipation member. The force dissipation member includes a central portion that is sized to detachably attach around the screw boss. The force dissipation member further includes at least two arms that extend outwardly from the central portion, wherein each arm of the at least two arms is attached to a different side of the two walls of the housing.

Abstract: A shingle coating asphalt composition is provided that is produced from a paving grade asphalt. The asphalt composition comprises a paving-grade asphalt that has been modified with one or more polymer additives; and a secondary additive comprising one or more of a viscosity reducing agent, a wax, a salt of a fatty acid ester, and an amide of a fatty acid. The shingle coating asphalt coating composition is used to make a shingle. The shingle includes a substrate, the asphalt, and roofing granules.

Abstract: A sleeve apparatus for weighting a structure, such as a canopy structure, that can also be used to display items on the structure via the items' attachment to the sleeve apparatus. The sleeve apparatus includes at least an elongated body having first and second ends, a first connector element connected to the first end of the elongated body that is capable of encircling and attaching to a rod member and/or a bar member and a second connector element connected to and extending from the second end of the elongated body that is capable of encircling and attaching to the same or a different rod member and/or bar member.

Abstract: Anti-parasitic compounds and uses thereof. Compounds comprising a C-terminal peptide adjuvant conjugated to an N-terminal peptide antigen via a protease-cleavable linker, said peptide adjuvant comprising a peptide analog of C5a, wherein said peptide antigen comprises an antigenic epitope of a parasitic organism, such as T. gondii. Methods of therapeutic or prophylactic treatment of a parasitic infections.

Abstract: Various embodiments include methods and vehicles, such as an autonomous vehicle, a semi-autonomous vehicle, etc., for collaboratively directing or configuring one or more headlights of a vehicle to avoid visually interfering with operation of an oncoming vehicle. Various embodiments may include receiving, by a first vehicle processor, a first collaborative lighting message from a second vehicle, wherein the first collaborative lighting message requests that the first vehicle direct one or more headlights of the first vehicle to avoid visual interference with operation of the second vehicle and directing one or more the headlights of the first vehicle in accordance with the collaborative lighting plan. Directing the headlights to avoid visual interference with operation of the second vehicle may include switching the headlights to a low-beam configuration.

Abstract: An automatic, autonomous predictive aircraft surface state event track (ASSET) system, includes a mobile device onboard an aircraft and a remote service in communication with the mobile device. The mobile device includes a processor, and an application that in turn includes machine instructions encoded on a non-transitory computer-readable storage medium. The processor executes the machine instructions to receive sensor data from aircraft onboard sensors, the sensor data indicating an operational state of the aircraft; and transmit the sensor data. The remote service receives the sensor data and includes a remote processor that executes machine instructions to compute an operational state of the aircraft; identify an aircraft event associated the aircraft; and using the aircraft operational data, the sensor data, and the event, predict that the aircraft will meet a next scheduled aircraft event within a specified time window.

Abstract: Extruded components for articles of footwear and methods of making such articles of footwear are disclosed. A carrier can be formed from a first material, the carrier including an attachment surface configured to attach to an upper and a receiving surface having a plurality of receptacles. A second material can be extruded into a plurality of the receptacles to form cushioning elements of a sole.

Abstract: A system for monitoring a position of a vehicle in a lane of a road, the system comprising: a processor; a first camera configured to output first image data relating to a surface of the road on a first side of the vehicle; a second camera configured to output second image data relating to a surface of the road on a second side of the vehicle, wherein the processor is configured to determine if the vehicle is at risk of straying outside the lane based on the first image data or the second image data and auxiliary data received by the processor

Abstract: A real-time recommendation system includes a non-transitory, computer-readable storage medium having encoded thereon instructions that a processor executes to receive data from data sources that includes one or more data records. The processor then identifies features in data of a data record, extracts and buffers the features, and applies the features to a feature detect mechanism. The feature detect mechanism includes feature detect algorithm and more recommender algorithms that are encapsulated in a feature detection object. The feature detection object may be a Strategy/Composite feature detection object that includes Strategy design patterns. The processor further executes to reject a feature in response to failures of the feature to match at least one of the Strategy design patterns, and in real time, select and install features that match one or more of the Strategy design patterns into one or more recommender algorithms.

Abstract: An article of footwear includes an upper and a sole coupled to the upper. The article of footwear includes an inflation system. The inflation system includes an inflatable bladder, a pump in fluid communication with the bladder, and a control circuitry operatively linked to the pump. The pump adjusts the air pressure of the inflatable bladder. The control circuitry receives a command signal from a remote device, and upon receipt of the command signal, the control circuitry transmits an actuation signal to the pump to adjust the air pressure of the inflatable bladder.

Abstract: Systems, apparatuses, methods, and computer program products are disclosed for predicting an entity, intent, and emotion based on weighted and segmented portions of captured speech. An example method includes capturing speech and separating the speech and/or text derived from the speech into a plurality of discrete segments. The example method further includes determining or generating metadata, the metadata an entity, an intent, an emotion, and a weight associated with each of the entity, the intent, the emotion. The example method further includes determining a next action based on the determined or generated entity, intent, and emotion of each of the plurality of discrete segments.

Abstract: A method, executed by a processor, includes the processor receiving signals information from a device located on a departing airplane; verifying an identification of the airplane and identifying an expected departure sequence of aircraft surface states; monitoring and identifying additional signals information received from the mobile device, including comparing the additional signals information to known data; logging the additional signals information, and processing the additional signals information, and determining the logged data corresponds to events indicative of an aircraft surface state; sending an aircraft surface state reached message to Local and Center flight management; and executing a statistical routine and providing statistical data from the execution relating to an occurrence of upcoming aircraft surface state event and sending the statistical data with the aircraft surface state message.