Patents by Inventor Paula Dennis

Paula Dennis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7655254
    Abstract: An implantable device includes a reservoir containing a suspension of an interferon in an amount sufficient to provide continuous delivery of the interferon at a therapeutically effective rate of 1 ng/day to 600 ?g/day to maintain and achieve therapeutic blood or plasma levels of the interferon throughout a substantial period of the administration period.
    Type: Grant
    Filed: February 3, 2006
    Date of Patent: February 2, 2010
    Assignee: Intarcia Therapeutics, Inc.
    Inventors: Paula Dennis, Michael A. Desjardin, Stan Lam, Kui Liu, James E. Matsuura, Latha Narayanan, Catherine M. Rohloff, Pauline C. Zamora
  • Publication number: 20060263433
    Abstract: A suspension formulation of interferon includes a non-aqueous, single-phase vehicle including at least one polymer and at least one solvent, the vehicle exhibiting viscous fluid characteristics, and an interferon contained in a particle formulation dispersed in the vehicle. The particle formulation includes a stabilizing component comprising one or more stabilizers selected from the group consisting of carbohydrates, antioxidants, and amino acids. The suspension formulation is characterized in that less than 10% of the interferon degrades over 3 months under an accelerated storage condition.
    Type: Application
    Filed: February 3, 2006
    Publication date: November 23, 2006
    Inventors: Rupal Ayer, Paula Dennis, Michael Desjardin, Stan Lam, Kui Liu, James Matsuura, Latha Narayanan, Catherine Rohloff, Pauline Zamora
  • Publication number: 20060251618
    Abstract: An implantable device includes a reservoir containing a suspension of an interferon in an amount sufficient to provide continuous delivery of the interferon at a therapeutically effective rate of 1 ng/day to 600 ?g/day to maintain and achieve therapeutic blood or plasma levels of the interferon throughout a substantial period of the administration period.
    Type: Application
    Filed: February 3, 2006
    Publication date: November 9, 2006
    Inventors: Paula Dennis, Michael Desjardin, Stan Lam, Kui Liu, James Matsuura, Latha Narayanan, Catherine Rohloff, Pauline Zamora