Abstract: A system and process for aggregating and displaying information about a plurality of gaming tables to a user comprising a stacking component and a console area. The console area displays one or more active tables, while the stacking component displays changing information about each table the user has open. The stacking component may include one or more sub-components or dialogs, including a table list dialog, a player information dialog, a hand information dialog and/or an action area dialog.

Abstract: The present invention provides new antifibrillogenic agents and peptides, compositions and cells containing same, compositions that bind to same, effective therapeutics for preventing or delaying the progression of, e.g., Alzheimer's disease and diabetes, methods for optimizing antifibrillogenic agents, and methods of using the antifibrillogenic agents, peptides, compositions, and cells of the invention for detecting and/or inhibiting amyloid fibril formation.

Abstract: A system and process for aggregating and displaying information about a plurality of gaming tables to a user comprising a stacking component and a console area. The console area displays one or more active tables, while the stacking component displays changing information about each table the user has open. The stacking component may include one or more sub-components or dialogs, including a table list dialog, a player information dialog, a hand information dialog and/or an action area dialog.

Abstract: Systems, methods, and apparatus relating to the use of Stirling engine technology to convert heat, such as from solar radiation, to mechanical work or electricity. Apparatus, systems, components, and methods relating to energy converting apparatus are described herein. In one aspect, the invention relates to the field alignment of panels and the assembly of a concentrator. In another aspect, a passive balancer is used in combination with a ring frame and other moving masses to reduce engine forces and vibration on the structure of the energy converting apparatus while maintaining properly constrained alignment of various suspended masses. In yet another aspect, the invention relates to various over-insolation control and management strategy to prevent overheating of the energy converting apparatus or components and subsystems thereof.

Abstract: In one aspect the invention relates to an electrical circuit for use with a generator having an output port, the circuit to modify one of an electric current or voltage from the generator. The circuit includes a rectifier to convert the alternating current from the generator to direct current, the rectifier having a first port and a second port, the rectifier first port in communication with the output port of the generator; and a direct current to alternating current inverter to convert the direct current from the rectifier to alternating current, the inverter having a first port and a second port, the first port of the inverter in communication with the second port of the rectifier. In one embodiment, the generator is a linear alternator positioned within an energy converting apparatus comprising a Stirling engine having a piston such that motion of the piston drives the linear alternator.

Abstract: The present invention is based on a Bacillus the spores and vegetative cells forms of which are a different colour because of differential presence of at least one carotenoid in the spore and vegetative cell forms of the Bacillus. The Bacillus may therefore be used in detection methods and biosensors. The Bacillus may also be used a colourant and a dye and in the generation of foods, food supplements, probiotic compositions, dyes, cosmetic, pharmaceuticals and vaccines. The Bacillus may also be used for the production of carotenoids, precursors thereof and downstream derivatives.

Abstract: Presenilin Associated Membrane Protein (PAMP), and nucleic acids encoding this protein, are provided. PAMP and PAMP nucleic acids provide diagnostic and therapeutic tools for evaluating and treating or preventing neurodevelopmental and neuropsychiatric disorders. In a specific embodiment, mutations in PAMP are diagnostic for schizophrenia. The invention further relates to screening, particularly using high-throughput screens and transgenic animal models, for compounds that modulate the activity of PAMP and presenilins. Such compounds, or gene therapy with PAMP, can be used in treating neurodevelopmental and neuropsychiatric disorders, particularly schizophrenia. In addition, the invention provides PAMP mutants, nucleic acids encoding for PAMP mutants, and transgenic animals expressing PAMP mutants, which in a preferred aspect result in biochemical, morphological, or neuropsychological changes similar to those associated with schizophrenia.

Abstract: The present invention provides new antifibrillogenic agents and peptides, compositions and cells containing same, compositions that bind to same, effective therapeutics for preventing or delaying the progression of, e.g., Alzheimer's disease and diabetes, methods for optimizing antifibrillogenic agents, and methods of using the antifibrillogenic agents, peptides, compositions, and cells of the invention for detecting and/or inhibiting amyloid fibril formation.

Abstract: The invention relates to modulators of ?-secretase and to methods and uses related thereto. In one embodiment the modulators do not modulate ?-secretase activity. In another embodiment the invention relates to presenilin complex component. In one embodiment the presenilin component is TMP21.

Abstract: New antifibrillogenic agents and compositions containing same, methods of using the antifibrillogenic agents and compositions for inhibiting amyloid fibril formation, and effective therapeutics for preventing or delaying the progression of, e g., Alzheimer's disease and diabetes.

Abstract: Methods and compositions which are useful in the treatment of amyloidosis. In particular, methods and compositions are provided for inhibiting, preventing and treating amyloid depositions, e.g. in pancreatic islets, wherein the amyloidotic deposits are islet amyloid polypeptide (IAPP)-associated amyloid deposition or deposits. The methods of the invention involved administering to a subject a therapeutic compound which inhibits IAPP-associated amyloid deposits. Accordingly, the compositions and method of the invention are useful for inhibiting IAPP-associated amyloidosis in disorders in which such amyloid deposition occurs, such an diabetes. The invention also provides a process for the preparation of cells suitable for transplantation into a mammal, which cells are capable of forming fibrils, said process comprising contacting the cells with an inhibitor of fibril formation. In particular the process prepares cells for use in a method of treating diabetes.

Abstract: Disclosed is a method for identifying substances that alter the interaction of a presenilin protein with a presenilin-binding protein, including contacting at least the interacting domain of a presenilin protein to a presenilin-binding protein in the presence of a test substance, and measuring the interaction of the presenilin protein and the presenilin-binding protein. Also disclosed is method for identifying substances that modulate the nuclear translocation of an armadillo protein, including providing a culture of cells that express the armadillo protein and a mutant presenilin protein, or a functional fragment thereof that binds an armadillo protein; contacting the culture with a test substance; inducing nuclear translocation of the armadillo protein in the cells; and measuring levels of nuclear armadillo protein as compared to a control as an indication of modulatory activity of the test substance.

Abstract: Presenilin Associated Membrane Protein (PAMP), and nucleic acids encoding this protein, are provided. PAMP and PAMP nucleic acids provide diagnostic and therapeutic tools for evaluating and treating or preventing neurodevelopmental and neuropsychiatric disorders. In a specific embodiment, mutations in PAMP are diagnostic for schizophrenia. The invention further relates to screening, particularly using high-throughput screens and transgenic animal models, for compounds that modulate the activity of PAMP and presenilins. Such compounds, or gene therapy with PAMP, can be used in treating neurodevelopmental and neuropsychiatric disorders, particularly schizophrenia. In addition, the invention provides PAMP mutants, nucleic acids encoding for PAMP mutants, and transgenic animals expressing PAMP mutants, which in a preferred aspect result in biochemical, morphological, or neuropsychological changes similar to those associated with schizophrenia.

Abstract: The present invention describes the identification, isolation, cloning, and determination of the Alzheimer Related Membrane Protein (ARMP) gene on chromosome 14 and a related gene, E5-1, on chromosome 1. Normal and mutant copies of both genes are presented. Transcripts and products of these genes are useful in detecting and diagnosing Alzheimer's disease, developing therapeutics for treatment of Alzheimer's disease, as well as the isolation and manufacture of the protein and the construction of transgenic animals expressing the mutant genes.

Abstract: A method and apparatus for managing heap memory for an application program in a data processing system. The system supports a basic addressing mode and an extended addressing mode. Programs operating in the basic addressing mode are limited to addressing using a first number of bits, program operating in the extended addressing mode are limited to addressing using a second number of bits, and the first number of bits is less than the second number of bits. One or more heap banks are established for an application program, with each heap bank having a quantity of memory space that is addressable by the program operating in basic addressing mode. The heap banks are managed by a system program operating in extended addressing mode. In response to each request from the application program that requires a quantity of memory space, one of the heap banks is selected for allocating the memory.

Abstract: New antifibrillogenic agents and compositions containing same, methods of using the antifibrillogenic agents and compositions for inhibiting amyloid fibril formation, and effective therapeutics for preventing or delaying the progression of, e g., Alzheimer's disease and diabetes.

Abstract: In vivo and in vitro methods of increasing amyloid deposition using amyloid-enhancing compounds are described. Methods of forming amyloid fibrils and screening for agents useful in treating amyloidosis are also described. Animals having non-naturally occurring amyloid deposits produced using the amyloid-enhancing compounds even further are described.

Abstract: A method and apparatus for the harvesting of royal jelly. The method comprises the use of a first matrix of cell-like structures in an arrangement typical of normal worker bee cells which have interconnected plugs placed in the back of the matrix. A queen bee may then lay this matrix of cells with eggs. Upon the eggs turning into larvae, the plugs may be removed and the plugs are provided in interconnected sets such that each set provides plugs for each alternate cell in the first matrix of cells. These plugs may then be fitted to a second matrix of cells which provide larger, queen-like cells at a spacing of substantially the same as the alternate cells in the first matrix. The second matrix may then be placed in a queenless hive for the bees to fill the larger cells of the second matrix with royal jelly which may then be harvested.