Patents by Inventor Paul A. Friedman

Paul A. Friedman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210275080
    Abstract: Systems, methods, devices, and techniques for analyzing and applying features of a T-wave derived from an electrocardiogram. A computing system can receive a set of data that characterizes an electrocardiogram of a patient. The system can analyze the set of data to identify a T-wave that occurs in the electrocardiogram. The system can determine values of one or more features of the T-wave and provide the information that identifies the values of the one or more features of the T-wave to a user.
    Type: Application
    Filed: August 31, 2017
    Publication date: September 9, 2021
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Peter A. Noseworthy, Bo Qiang, Paul A. Friedman, Alan M. Sugrue, Vaclav Kremen, Bryan L. Striemer, Charles J. Bruce, Virend K. Somers, Kevin E. Bennet, Michael J. Ackerman, Samuel J. Asirvatham, John J. Dillon, Christopher V. DeSimone
  • Publication number: 20210228861
    Abstract: This document describes methods and materials for improving treatment of hypertension. For example, this document describes methods and devices for electroporation of nerves in the renal area to treat hypertension.
    Type: Application
    Filed: April 14, 2021
    Publication date: July 29, 2021
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. ASIRVATHAM, Paul A. Friedman
  • Publication number: 20210204858
    Abstract: Data is generated that describes features of an ECG of a subject. This generation can include receiving ECG data that was generated to reflect cardiac activity of a particular mammal; submitting the ECG data to a plurality of cardiac classifiers, each cardiac classifier configured to identify, in the ECG, at least some of a plurality of cardiac features that are within a particular feature-class; receiving, from each of the plurality of cardiac classifiers, a classification message containing data of the cardiac classifiers identifying of cardiac features in the ECG; and assembling, from the received classification messages, ECG features for the ECG, the ECG features identifying at least some features of different feature-classes.
    Type: Application
    Filed: May 23, 2019
    Publication date: July 8, 2021
    Inventors: Itzhak Zachi Attia, Paul A. Friedman, Peter A. Noseworthy
  • Patent number: 11027115
    Abstract: This document describes methods and materials for improving treatment of hypertension. For example, this document describes methods and devices for electroporation of nerves in the renal area to treat hypertension.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: June 8, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Paul A. Friedman
  • Patent number: 11020589
    Abstract: Systems and methods for epicardial pacing are provided. For example, this document provides epicardial pacing using a percutaneously delivered bifurcated pacing lead that has multiple electrodes that are directionally insulated to prevent extracardiac stimulation, including prevention of phrenic stimulation. In addition, the devices, systems, and methods provided can be used for ablation, defibrillation, and/or defibrillation in combination with pacing.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: June 1, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Faisal F. Syed, Charles J. Bruce, Christopher V. DeSimone, Paul A. Friedman, Samuel J. Asirvatham, Tomas Kara, Pavel Leinveber, Miroslav Novak, Zdenek Starek, Jiri Wolf
  • Publication number: 20210106807
    Abstract: This document relates to materials and methods for circulatory bypass of a ventricle in the heart of a mammal. For example, materials and methods for bypassing a permanently or temporarily impaired left ventricle in the heart of a mammal (e.g., a human) are provided.
    Type: Application
    Filed: November 25, 2020
    Publication date: April 15, 2021
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Soon J. Park, Paul A. Friedman, Charles J. Bruce, Sudhir S. Kushwaha
  • Publication number: 20200397525
    Abstract: Devices and methods for the treatment of heart conditions, and other medical purposes, include cardiac pacing systems. For example, this document describes temporary transvenous endocardial pacemaker systems and devices for deploying such systems without the need for conventional imaging procedures.
    Type: Application
    Filed: February 27, 2019
    Publication date: December 24, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Peter M. Pollak, Samuel J. Asirvatham, Charles J. Bruce, Paul A. Friedman
  • Publication number: 20200397313
    Abstract: Systems, methods, devices, and techniques for estimating an ejection-fraction characteristic of a mammal. An electrocardiogram (ECG) procedure is performed on a mammal, and a computer system obtains ECG data that describes results of the ECG over a period of time. The system provides a predictive input that is based on the ECG data to an ejection-fraction predictive model, such as a neural network or other machine-learning model. In response, the ejection-fraction predictive model processes the input to generate an estimated ejection-fraction characteristic of the mammal. The system outputs the estimated ejection-fraction characteristic of the mammal for presentation to a user.
    Type: Application
    Filed: October 4, 2018
    Publication date: December 24, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Itzhak Zachi Attia, Paul A. Friedman, Francisco Lopez-Jimenez, Suraj Kapa
  • Patent number: 10869957
    Abstract: This document relates to materials and methods for circulatory bypass of a ventricle in the heart of a mammal. For example, materials and methods for bypassing a permanently or temporarily impaired left ventricle in the heart of a mammal (e.g., a human) are provided.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: December 22, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Soon J. Park, Paul A. Friedman, Charles J. Bruce, Sudhir S. Kushwaha
  • Publication number: 20200376274
    Abstract: Devices and methods can be used for artificial cardiac pacing and/or resynchronization. For example, this document provides improved electrodes for stimulating and sensing electrical activity of the heart, and provides pacing and resynchronization systems incorporating such electrodes. While the devices and methods provided herein are described primarily in the context of pacing, it should be understood that resynchronization can additionally or alternatively be performed in an analogous manner, and that the scope of this disclosure includes such subject matter.
    Type: Application
    Filed: August 20, 2020
    Publication date: December 3, 2020
    Inventors: Paul A. Friedman, Charles J. Bruce, Samuel J. Asirvatham
  • Publication number: 20200330780
    Abstract: This document relates to methods and materials for improving artificial cardiac pacing and/or resynchronization. For example, this document relates to methods and devices for artificial cardiac pacing and/or resynchronization by stimulating the His bundle.
    Type: Application
    Filed: October 24, 2018
    Publication date: October 22, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Paul A. Friedman
  • Patent number: 10780280
    Abstract: Devices and methods can be used for artificial cardiac pacing and/or resynchronization. For example, this document provides improved electrodes for stimulating and sensing electrical activity of the heart, and provides pacing and resynchronization systems incorporating such electrodes. While the devices and methods provided herein are described primarily in the context of pacing, it should be understood that resynchronization can additionally or alternatively be performed in an analogous manner, and that the scope of this disclosure includes such subject matter.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: September 22, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Paul A. Friedman, Charles J. Bruce, Samuel J. Asirvatham
  • Publication number: 20200268513
    Abstract: This document describes methods and devices for securing epicardial devices. For example, this document describes methods and devices for securing epicardial devices by passing a sheath into a pericardial space of a patient through a first percutaneous access site, passing a guidewire through the sheath into the pericardial space of the patient, passing the guidewire through a transverse sinus of the patient, passing a snare device into the pericardial space through a second percutaneous access site, and capturing a free end portion of the guidewire using the snare device.
    Type: Application
    Filed: September 12, 2018
    Publication date: August 27, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Paul A. Friedman
  • Patent number: 10694965
    Abstract: This document provides methods and materials related to the non-invasive measurement of analytes in blood.
    Type: Grant
    Filed: January 25, 2018
    Date of Patent: June 30, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Paul A. Friedman, Kevin E. Bennet, Charles J. Bruce, Virend K. Somers
  • Publication number: 20200197687
    Abstract: This document describes methods and materials for improving treatment of hypertension. For example, this document describes methods and devices for electroporation of nerves in the renal area to treat hypertension.
    Type: Application
    Filed: February 28, 2020
    Publication date: June 25, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Paul A. Friedman
  • Publication number: 20200113470
    Abstract: A system obtains a maternal electrocardiogram (ECG) signal that represents an ECG of a pregnant mother during a first time interval. The system further obtains a mixed maternal-fetal ECG signal that represents a combined ECG of the mother and her fetus during the first time interval; processes the maternal ECG signal and the mixed maternal-fetal ECG signal to generate a fetal ECG signal that represents the ECG of the fetus during the time interval, the fetal ECG signal substantially excluding the maternal ECG signal; and provides an output based on the fetal ECG signal.
    Type: Application
    Filed: February 23, 2018
    Publication date: April 16, 2020
    Inventors: Paul A. Friedman, Dorothy J. Ladewig, Itzhak Zachi Attia, Kyle D. Traynor
  • Publication number: 20200093825
    Abstract: Methods, kits, and compositions for treating dry eye disorders and other related eye diseases are provided, wherein the methods, kits, and compositions utilize a JAK inhibitor.
    Type: Application
    Filed: November 18, 2019
    Publication date: March 26, 2020
    Inventors: Paul A. Friedman, Jordan S. Fridman, Monica E. Luchi, William V. Williams
  • Publication number: 20200093932
    Abstract: Provided are methods relating to the treatment of cancer with a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101 in combination with an inhibitor of the tryptophan metabolism pathway, e.g., an indoleamine-2,3-dioxygenase (IDO) inhibitor or a tryptophan-2, 3-dioxygenase (TDO) inhibitor.
    Type: Application
    Filed: December 1, 2017
    Publication date: March 26, 2020
    Inventors: Paul Friedman, Scott Eliasof, Adrian Senderowicz, Andres Tellez, Douglas Lazarus, Lata Jayaraman
  • Publication number: 20190298210
    Abstract: This document provides devices and methods for monitoring patient health parameters using a wearable monitoring device. For example, this document provides algorithms for artifact rejection and for detection of cardiac events using a remote health parameter monitoring system.
    Type: Application
    Filed: July 1, 2014
    Publication date: October 3, 2019
    Inventors: Kevin E. Bennet, Charles J. BRUCE, Paul A. FRIEDMAN, Virend K. SOMERS
  • Publication number: 20190246966
    Abstract: Systems, methods, and other techniques for estimating the level of an analyte present in a patient during a time interval using electrocardiogram (ECG) signals. The estimate can be improved using information about the patient's posture.
    Type: Application
    Filed: September 12, 2017
    Publication date: August 15, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Paul A. Friedman, Michael J. Ackerman, Samuel J. Asirvatham, Itzhak Zachi Attia, Kevin E. Bennet, Charles J. Bruce, John J. Dillon, Jennifer L. Dugan, Dorothy J. Ladewig, Virend K. Somers