Abstract: A tubular reactor characterized by having short static mixing elements separated by coalescing zones is used to conduct multiphase liquid/liquid reactions. Small droplets of one of the phases are dispersed into the other phase by the static mixing elements. These droplets coalesce and at least partially phase separate as the mixture passes through the subsequent coalescing zone. The tubular reactor is particularly suitable for nitrating organic compounds while forming low levels of improperly nitrated by-products and low levels of nitrophenolics.

Abstract: The present invention provides a method of inhibiting angiogenesis within a tissue by providing exogenous PEDF to cells associated with the tissue. The presence of exogenous PEDF inhibits angiogenesis within the tissue, in part by interfering with the ability of vascular endothelia to expand within the tissue. The invention also provides a method for determining the severity of a tumor be assaying for the presence of PEDF within the tumor. To facilitate the inventive methods, the present invention provides pharmaceutical compositions including sources of PEDF.

Abstract: A tubular reactor characterized by having short static mixing elements separated by coalescing zones is used to conduct multiphase liquid/liquid reactions. Small droplets of one of the phases are dispersed into the other phase by the static mixing elements. These droplets coalesce and at least partially phase separate as the mixture passes through the subsequent coalescing zone. The tubular reactor is particularly suitable for nitrating organic compounds while forming low levels of improperly nitrated by-products and low levels of nitrophenolics.

Abstract: A tubular reactor characterized by having short static mixing elements separated by coalescing zones is used to conduct multiphase liquid/liquid reactions. Small droplets of one of the phases are dispersed into the other phase by the static mixing elements. These droplets coalesce and at least partially phase separate as the mixture passes through the subsequent coalescing zone. The tubular reactor is particularly suitable for nitrating organic compounds while forming low levels of improperly nitrated by-products and low levels of nitrophenolics.

Abstract: A tubular reactor characterized by having short static mixing elements separated by coalescing zones is used to conduct multiphase liquid/liquid reactions. Small droplets of one of the phases are dispersed into the other phase by the static mixing elements. These droplets coalesce and at least partially phase separate as the mixture passes through the subsequent coalescing zone. The tubular reactor is particularly suitable for nitrating organic compounds while forming low levels of improperly nitrated by-products and low levels of nitrophenolics.

Abstract: A tubular reactor characterized by having short static mixing elements separated by coalescing zones is used to conduct multiphase liquid/liquid reactions. Small droplets of one of the phases are dispersed into the other phase by the static mixing elements. These droplets coalesce and at least partially phase separate as the mixture passes through the subsequent coalescing zone. The tubular reactor is particularly suitable for nitrating organic compounds while forming low levels of improperly nitrated by-products and low levels of nitrophenolics.

Abstract: A tubular reactor characterized by having short static mixing elements separated by coalescing zones is used to conduct multiphase liquid/liquid reactions. Small droplets of one of the phases are dispersed into the other phase by the static mixing elements. These droplets coalesce and at least partially phase separate as the mixture passes through the subsequent coalescing zone. The tubular reactor is particularly suitable for nitrating organic compounds while forming low levels of improperly nitrated by-products and low levels of nitrophenolics.

Abstract: Shear mixing apparatuses and associated methods are disclosed for producing small gas bubbles of a diameter of less than about 0.1 millimeters in a liquid, whereby mass transfer of the gas into the liquid is improved (as compared to the mass transfer achieved by conventional large bubble generators under the same circumstances) in applications benefiting by such improved mass transfer, involving injecting a gas under pressure via one or more orifices into a liquid that is flowing at a velocity sufficient to cause bubbles formed at the orifice(s) to subdivide to the desired small bubble size.

Abstract: In a cooling surface cladding for polygonal chambers of steam generators with a hopper-shaped floor and fired on the circulating fluidised bed principle, which consists partially of substantially vertical finned tubes extending in the manner of walls between manifolds and converging curves in the floor region to form a hopper, two opposite finned tube walls (1) in the hopper region, viewed from top to bottom, first form a hopper wall (1') inclined from the vertical over their entire width and then form at least one vertical hopper wall (1") of decreasing width and with partially oblique manifolds (2). In the region of the hopper, viewed from top to bottom, the adjacent tube wall (3) and the tube wall (3') opposite it form first a vertical hopper wall of diminishing width and with oblique manifolds (4) and then an inclined side wall (3") of the hopper of constantly reducing width.

Abstract: A squeezable spread having a fat phase of less than 3 wt. % of a hardstock combined with about 97 to about 99% of liquid vegetable oil is described. The hardstock is a fully hardened low erucic rapeseed oil and the liquid vegetable oil is non-hydrogenated containing no solid fat at temperatures of 45.degree. F. and above.