Patents by Inventor Paul A. Holmes

Paul A. Holmes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10703199
    Abstract: The present invention provides a vehicle differential linked to and is arranged to move with a control arm and/or an a-arm of a suspension assembly, providing a floating differential suspension system. The differential is adapted to be mounted independent of the vehicle frame. Advantages of a floating differential suspension system include better alignment between the differential and the transfer case, reduced drive shaft movement in the vertical direction, minimal plunge at the drive shaft splines, longer axle length with increased wheel travel, decreased angle at mechanical connections, reduced camber change through the wheel travel, lower frame construction with increased range of suspension travel, and reduced risk of vehicle roll over without compromising the range of suspension travel.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: July 7, 2020
    Assignee: Amanda Bent-Bolt Company
    Inventors: Robert Gruschow, Wesley Scott Holmes, Nicholas Paul Stephey
  • Publication number: 20200166528
    Abstract: Methods for improving assays of biological samples are provided, including assays of small volume biological samples, such as blood samples obtained from a fingerstick. The methods include steps of selecting a baseline assay; providing a first revised assay by altering an aspect, a reagent, or a step of the baseline assay; comparing the results of the baseline assay and first revised assay; and identifying the first revised assay as an improved assay if the results of the first revised assay are similar to, are substantially the same as, or are better than, the results of the baseline assay. The methods may be iterated. Alterations include reducing sample volume; setting temperature; reducing step number and duration; altering reagent composition and number; and altering detection. Improved assays may reduce the duration, cost, or complexity of the assay, may improve assay sensitivity, accuracy, or reliability, and may provide synergistic improvements.
    Type: Application
    Filed: August 27, 2019
    Publication date: May 28, 2020
    Inventors: Paul Patel, Ian Gibbons, Elizabeth A. Holmes
  • Publication number: 20200063185
    Abstract: Reagents, assays, methods, kits, devices, and systems for rapid measurement of cholesterol and cholesterol sub-fractions from a blood sample are provided. Total cholesterol, low density lipoprotein cholesterol, and high density lipoprotein cholesterol can be measured in a single assay using kinetic measurements, under conditions in which cholesterol sub-species are converted to a detectable product at distinct rates. The detectable product is measured at different times after assay initiation. A lipase, cholesterol esterase, cholesterol oxidase and a peroxidase may be used together to produce colored product in amounts directly proportional to the quantity of cholesterol converted. Methods for calculating very-low density lipoprotein cholesterol levels by further including triglyceride measurements are disclosed.
    Type: Application
    Filed: August 2, 2019
    Publication date: February 27, 2020
    Inventors: Douglas Matje, Ian Gibbons, Paul Patel, Elizabeth A. Holmes
  • Publication number: 20200017299
    Abstract: Systems, method and computer readable medium are provided for automated storage and retrieval. User authentication information is received via a user interface for a dynamic storage and retrieval device. The user identity is verified based upon the authentication information and previously stored authentication data. order information is retrieved for an order associated with the user following the verifying of user identity, the order information indicating one or more locations for items associated with the order. Instructions are transmitted to initiate a physical opening of at least one of the dynamic storage and retrieval device and at least one static storage location to enable the user to retrieve at least one item of the order, the static storage location including a controller controlling a locking mechanism and communicatively coupled to the dynamic storage and retrieval device.
    Type: Application
    Filed: July 12, 2019
    Publication date: January 16, 2020
    Inventors: Paul Edward Durkee, Stuart William Clark, Colin Holmes, Jason Shaffer, Mark Ibbotson, John Suarez
  • Publication number: 20200017300
    Abstract: Described in detail herein is an autonomous object storage and retrieval system. In one embodiment, an object storage and retrieval system includes a computing system hosting a service application and in communication with a database and storage towers configured to store and dispense physical objects. Each storage tower is in communication with the computing system and has an octagonal prism-shaped housing. Each storage tower includes, a shelving unit disposed within the housing, the shelving unit configured to one or more of the physical objects, a controller, a transport apparatus, an input device, an interactive display, and a repository. The computing system can transmit instructions to the first storage tower to render the status of the first physical object on the interactive display of the storage tower.
    Type: Application
    Filed: July 12, 2019
    Publication date: January 16, 2020
    Inventors: Paul Edward Durkee, Jason D. Shaffer, Mark Ibbotson, John Suarez, Colin Holmes
  • Patent number: 10476971
    Abstract: Configurable and self-optimizing business process applications can be used in conjunction with features of a content management system, for example including generating and providing guidance relating to a decision or action point within a workflow instance, allowing a user to invoke an exception that includes a deviation from a set of actions defined by the business process application, saving a modified version of the business process application in the content management repository, and monitoring performance metrics of the business process application and the modified business process application when used by additional users in additional workflow instances. Methods, systems, and articles of manufacture are described.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: November 12, 2019
    Assignee: Alfresco Software, Inc.
    Inventors: Paul Holmes-Higgin, David Caruana
  • Publication number: 20190293665
    Abstract: Methods, compositions, systems, and devices are provided for performing and analyzing agglutination assays. In one aspect, methods for image analysis of agglutination assays are provided. In another aspects, methods for performing agglutination assays are provided. In one aspect, the methods may be used for the detection of various molecules, including viruses or antibodies against a virus. In another aspect, the methods can be used to determine effective immunization of a subject.
    Type: Application
    Filed: March 29, 2019
    Publication date: September 26, 2019
    Inventors: Paul Patel, Samartha Anekal, Ian Gibbons, Elizabeth A. Holmes, Swapna Joshi
  • Patent number: 10422806
    Abstract: Methods for improving assays of biological samples are provided, including assays of small volume biological samples, such as blood samples obtained from a fingerstick. The methods include steps of selecting a baseline assay; providing a first revised assay by altering an aspect, a reagent, or a step of the baseline assay; comparing the results of the baseline assay and first revised assay; and identifying the first revised assay as an improved assay if the results of the first revised assay are similar to, are substantially the same as, or are better than, the results of the baseline assay. The methods may be iterated. Alterations include reducing sample volume; setting temperature; reducing step number and duration; altering reagent composition and number; and altering detection. Improved assays may reduce the duration, cost, or complexity of the assay, may improve assay sensitivity, accuracy, or reliability, and may provide synergistic improvements.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: September 24, 2019
    Assignee: Theranos IP Company, LLC
    Inventors: Paul Patel, Ian Gibbons, Elizabeth A. Holmes
  • Patent number: 10420982
    Abstract: System and methods are provided for prompting a user to perform an exercise and to monitor the exercise. The form of the user may be monitored, such as with one or more video cameras and/or other sensors, to determine how well the user is performing the exercise. Energy expenditure is estimated based factors that include the type of the exercise, the form of the user and a contribution value that associates energy expenditure with form.
    Type: Grant
    Filed: June 4, 2013
    Date of Patent: September 24, 2019
    Assignee: NIKE, Inc.
    Inventors: Tesa Aragones, Adriana Guerrero, Steve Holmes, Christina S. Self, Aaron B. Weast, Paul Winsper, Jay C. Blahnik, Adam Carroll
  • Publication number: 20190283575
    Abstract: The present invention provides a vehicle differential linked to and is arranged to move with a control arm and/or an a-arm of a suspension assembly, providing a floating differential suspension system. The differential is adapted to be mounted independent of the vehicle frame. Advantages of a floating differential suspension system include better alignment between the differential and the transfer case, reduced drive shaft movement in the vertical direction, minimal plunge at the drive shaft splines, longer axle length with increased wheel travel, decreased angle at mechanical connections, reduced camber change through the wheel travel, lower frame construction with increased range of suspension travel, and reduced risk of vehicle roll over without compromising the range of suspension travel.
    Type: Application
    Filed: June 7, 2019
    Publication date: September 19, 2019
    Inventors: Robert GRUSCHOW, Wesley Scott HOLMES, Nicholas Paul STEPHEY
  • Patent number: 10392650
    Abstract: Reagents, assays, methods, kits, devices, and systems for rapid measurement of cholesterol and cholesterol sub-fractions from a blood sample are provided. Total cholesterol, low density lipoprotein cholesterol, and high density lipoprotein cholesterol can be measured in a single assay using kinetic measurements, under conditions in which cholesterol sub-species are converted to a detectable product at distinct rates. The detectable product is measured at different times after assay initiation. A lipase, cholesterol esterase, cholesterol oxidase and a peroxidase may be used together to produce colored product in amounts directly proportional to the quantity of cholesterol converted. Methods for calculating very-low density lipoprotein cholesterol levels by further including triglyceride measurements are disclosed.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: August 27, 2019
    Assignee: Theranos IP Company, LLC
    Inventors: Douglas Matje, Ian Gibbons, Paul Patel, Elizabeth A. Holmes
  • Patent number: 10369412
    Abstract: Systems and methods for prompting a user to perform an exercise and monitoring the exercise are provided. Multiple independent sensors or sensor systems may be used to calculate energy expenditure. Various criteria may be used to manually or automatically select the independent sensor or sensor system or combination that will be used with the energy expenditure calculations.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: August 6, 2019
    Assignee: NIKE, Inc.
    Inventors: Tesa Aragones, Adriana Guerrero, Steve Holmes, Christina S. Self, Aaron B. Weast, Paul Winsper, Jay C. Blahnik
  • Patent number: 10358029
    Abstract: The present invention provides a vehicle differential linked to and is arranged to move with a control arm and/or an a-arm of a suspension assembly, providing a floating differential suspension system. The differential is adapted to be mounted independent of the vehicle frame. Advantages of a floating differential suspension system include better alignment between the differential and the transfer case, reduced drive shaft movement in the vertical direction, minimal plunge at the drive shaft splines, longer axle length with increased wheel travel, decreased angle at mechanical connections, reduced camber change through the wheel travel, lower frame construction with increased range of suspension travel, and reduced risk of vehicle roll over without compromising the range of suspension travel.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: July 23, 2019
    Assignee: Amanda Bent-Bolt Company
    Inventors: Robert Gruschow, Wesley Scott Holmes, Nicholas Paul Stephey
  • Patent number: 9962704
    Abstract: A specimen collection container includes inner and outer tubes. The inner tube includes a bottom end, a top end, and a sidewall extending therebetween defining an interior. The sidewall includes an inner surface and an outer surface having at least one annular protrusion extending therefrom. The inner tube includes at least one funnel portion adjacent the top end for directing a specimen into the inner tube interior, and an annular ring disposed about a portion of the outer surface of the sidewall adjacent the top end. The outer tube includes a bottom end, a top end, and a sidewall extending therebetween, the sidewall having an outer surface and an inner surface defining an annular recess adapted to receive a portion of the annular protrusion therein. The inner tube is disposed within the outer tube and a portion of the top end of the outer tube abuts the annular ring.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: May 8, 2018
    Assignee: Becton, Dickinson and Company
    Inventors: Benjamin R. Bartfeld, Robert G. Ellis, Robert S. Golabek, Jr., Nancy Dubrowny, Girish Parmar, Paul Holmes, Alex Blekher, Michael Delk
  • Patent number: 9948604
    Abstract: Hybrid, configurable business process applications can be used in conjunction with features of a content management system. For example, a first content management system installation executes a workflow instance based on a business process application whose definition is maintained in by the first content management system installation and synchronizes a workflow state of the workflow instance to a second content management system installation using a mirrored workflow state in which both content of the workflow state and metadata characterizing parameters of the workflow state are mirrored from the first content management system repository to the second content management system repository such that a content item retained in the second content management system repository is accessed for use in the workflow instance via the mirrored workflow state at the second content management system repository. Methods, systems, and articles of manufacture are described.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: April 17, 2018
    Assignee: Alfresco Software, Inc.
    Inventors: David Caruana, Paul Holmes-Higgin
  • Publication number: 20170337255
    Abstract: A workflow executed by an on-premise installation of the content management system can include a cloud workflow and an on-premise workflow relating to on-premise content retained in an on-premise repository managed by the on-premise installation of the content management system. A synchronization can be initiated between the on-premise content and a cloud copy of the on-premise content to reflect a change to either of the on-premise content or the cloud copy in the other of the on-premise content and the cloud copy. The cloud copy can exist at a location managed by a cloud-based installation of the content management system. Upon detection that the cloud workflow has been completed by the location using the cloud copy, a resumption of the on-premise workflow can be triggered using the synchronization between the on-premise content and the cloud copy of the on-premise content. Related systems, methods, products, etc. are described.
    Type: Application
    Filed: June 5, 2017
    Publication date: November 23, 2017
    Inventors: Paul Holmes-Higgin, Frederik Heremans, Tijs Rademakers, Joram Barrez
  • Patent number: 9805106
    Abstract: Content maintained in a first repository of a first installation (which can optionally be an on-premise installation) of a content management system, as well as metadata associated with the content, can be shared via an approach in which content items maintained in the first repository are synchronized with a copy of the content items maintained in a second repository of a second installation (which can optionally be a cloud-based installation). The first installation can be optionally firewall protected. The copy of the content items can be accessed by collaborative users both within and external to a firewall. Related systems, methods, products, etc. are described.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: October 31, 2017
    Assignee: Alfresco Software, Inc.
    Inventors: Neil McErlean, Tuna Aksoy, Nick Burch, Michael Farman, Paul Holmes-Higgin, John Newton, Brian Remmington, Mark Rogers, Jan Vonka, David Webster
  • Patent number: 9672261
    Abstract: A workflow executed by an on-premise installation of the content management system can include a cloud workflow and an on-premise workflow relating to on-premise content retained in an on-premise repository managed by the on-premise installation of the content management system. A synchronization can be initiated between the on-premise content and a cloud copy of the on-premise content to reflect a change to either of the on-premise content or the cloud copy in the other of the on-premise content and the cloud copy. The cloud copy can exist at a location managed by a cloud-based installation of the content management system. Upon detection that the cloud workflow has been completed by the location using the cloud copy, a resumption of the on-premise workflow can be triggered using the synchronization between the on-premise content and the cloud copy of the on-premise content. Related systems, methods, products, etc. are described.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: June 6, 2017
    Assignee: Alfresco Software, Inc.
    Inventors: Paul Holmes-Higgin, Frederik Heremans, Tijs Rademakers, Joram Barrez
  • Patent number: D874888
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: February 11, 2020
    Inventors: Ruth Niles, Paul Holmes
  • Patent number: D875524
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: February 18, 2020
    Inventors: Paul Holmes, Ruth Niles