Patents by Inventor Paul A. Koetsier

Paul A. Koetsier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation of High Molecular Weight DNA Using Beads
    Publication number: 20230151350
    Abstract: Provided herein is a method for isolating high molecular weight (HMW) DNA using beads that are at least 200 ?m in diameter that utilizes a device for retaining the beads and where the purified DNA eluant exits the device without shearing the HMW DNA. In some embodiments, the method comprises precipitating the DNA onto the beads, washing the beads in the device, and then eluting the DNA from the beads therein while substantially avoiding shear. Compositions and kits for practicing the method are also provided.
    Type: Application
    Filed: January 18, 2023
    Publication date: May 18, 2023
    Applicant: New England Biolabs, Inc.
    Inventors: Paul A. Koetsier, Barbara W. Taron, Eric J. Cantor
  • Isolation of high molecular weight DNA using beads
    Patent number: 11591591
    Abstract: Provided herein is a method for isolating high molecular weight (HMW) DNA using beads that are at least 200 ?m in diameter that utilizes a device for retaining the beads and where the purified DNA eluant exits the device without shearing the HMW DNA. In some embodiments, the method comprises precipitating the DNA onto the beads, washing the beads in the device, and then eluting the DNA from the beads therein while substantially avoiding shear. Compositions and kits for practicing the method are also provided.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: February 28, 2023
    Assignee: New England Biolabs, Inc.
    Inventors: Paul A. Koetsier, Barbara W. Taron, Eric J. Cantor
  • Isolation of High Molecular Weight DNA Using Beads
    Publication number: 20210054363
    Abstract: Provided herein is a method for isolating high molecular weight (HMW) DNA using beads that are at least 200 ?m in diameter that utilizes a device for retaining the beads and where the purified DNA eluant exits the device without shearing the HMW DNA. In some embodiments, the method comprises precipitating the DNA onto the beads, washing the beads in the device, and then eluting the DNA from the beads therein while substantially avoiding shear. Compositions and kits for practicing the method are also provided.
    Type: Application
    Filed: August 22, 2019
    Publication date: February 25, 2021
    Applicant: New England Biolabs, Inc.
    Inventors: Paul A. Koetsier, Barbara W. Taron, Eric J. Cantor