Abstract: A clip cartridge for supporting a plurality of clips is provided. The clip cartridge includes a body defining a plurality of clip chambers each configured and dimensioned to receive a clip therein. Interlocking structure is provided on each end of the cartridge to facilitate attachment of a multiplicity of clip cartridges together. Clip cartridges housing different size clips have substantially identical external dimensions and internal dimensions which accommodate for the different size clips. The uniformity of the external dimensions of the cartridges housing different size clips facilitates attachment of the cartridges housing different size clips.