Abstract: The invention relates to a novel group of compounds of Formula (I) or salts thereof: wherein Y, Z1, Z2, R1, R4, R5 and n are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to pharmaceutical compositions comprising said compounds, methods of treatment of diseases mediated by PKB using said compounds and methods for preparing compounds of Formula (I).

Abstract: A guide operates in the creation of a bone spur to facilitate harvesting a quadriceps tendon and includes an end having a width equal to a desired graft width with a terminal slope equal to a cutting angle desired. In use, the guide may be initially positioned parallel to the femur to form guide cuts in the patella. The guide is then rotated ninety degrees to allow an angled cut at the guide cut. The guide is again rotated, this time one hundred eighty degrees and a second angled cut made on the other guide cut. A final lateral cut is made and the bone spur may be lifted from the patella.

Abstract: The present disclosure provides a tendon repair anchor. An anchor plug is inserted into an anchor receptacle seated in a bone of a graft recipient. Sloped protrusions on the anchor plug interact with protrusions in the anchor receptacle to secure the anchor plug within the anchor receptacle and generally allow movement in a direction that more tightly secures the tendon graft to the bone. By allowing such unidirectional movement, slack in the sutures that secure the tendon graft to the anchor plug will not prevent the tendon graft from being properly positioned relative to the bone. Proper placement of the tendon graft allows for better healing and improves the likelihood of proper tendon replacement and tensioning.

Abstract: The present disclosure provides a dual-blade tendon cutting apparatus and cartridge for multiple apparatuses. Exemplary aspects of the present disclosure relate to a cutting implement that comprises two parallel blades that are spaced apart from one another by a predefined distance. The distance between the blades determines a lateral size of a graft being taken from the quadriceps tendon. To simplify matters for the surgeon, a cartridge is provided with three different blade sets. Much like a razor that has a disposable head, the cutting implement may attach to a desired blade set and be used.

Abstract: A guide is disclosed that operates to guide in the creation of a bone spur to facilitate harvesting a quadriceps tendon and includes an end having a width equal to a desired graft width with a terminal slope equal to a cutting angle desired. In use, the guide may be initially positioned parallel to the femur to form guide cuts in the patella. The guide is then rotated ninety degrees to allow an angled cut at the guide cut. The guide is again rotated, this time one hundred eighty degrees and a second angled cut made on the other guide cut. A final lateral cut is made and the bone spur may be lifted from the patella.

Abstract: A guide is disclosed that operates to guide in the creation of a bone spur to facilitate harvesting a quadriceps tendon and includes an end having a width equal to a desired graft width with a terminal slope equal to a cutting angle desired. In use, the guide may be initially positioned parallel to the femur to form guide cuts in the patella. The guide is then rotated ninety degrees to allow an angled cut at the guide cut. The guide is again rotated, this time one hundred eighty degrees and a second angled cut made on the other guide cut. A final lateral cut is made and the bone spur may be lifted from the patella.

Abstract: A guide is disclosed that operates to guide in the creation of a bone spur to facilitate harvesting a quadriceps tendon and includes an end having a width equal to a desired graft width with a terminal slope equal to a cutting angle desired. In use, the guide may be initially positioned parallel to the femur to form guide cuts in the patella. The guide is then rotated ninety degrees to allow an angled cut at the guide cut. The guide is again rotated, this time one hundred eighty degrees and a second angled cut made on the other guide cut. A final lateral cut is made and the bone spur may be lifted from the patella.

Abstract: Provided is a wireless charging loop antenna. The wireless charging loop antenna includes an extracorporal planar loop antenna and an intracorporal planar loop antenna. The intracorporal planar loop antenna is disposed inside a body, and the extracorporal planar loop antenna is disposed on a skin outside the body. The extracorporal planar loop antenna includes an extracorporal antenna substrate, an extracorporal loop radiation patch, paired connection radiation patches and a patch capacitor. The extracorporal loop radiation patch is provided with at least one extracorporal radiation patch gap. The patch capacitor is disposed at one of the at least one extracorporal radiation patch gap. The extracorporal loop radiation patch and the paired connection radiation patches form a circuit. The extracorporal loop radiation patch, the paired connection radiation patches and the patch capacitor are all on a same surface of the extracorporal antenna substrate.

Abstract: Provided is a wireless charging loop antenna. The wireless charging loop antenna includes an extracorporal planar loop antenna and an intracorporal planar loop antenna. The intracorporal planar loop antenna is disposed inside a body, and the extracorporal planar loop antenna is disposed on a skin outside the body. The extracorporal planar loop antenna includes an extracorporal antenna substrate, an extracorporal loop radiation patch, paired connection radiation patches and a patch capacitor. The extracorporal loop radiation patch is provided with at least one extracorporal radiation patch gap. The patch capacitor is disposed at one of the at least one extracorporal radiation patch gap. The extracorporal loop radiation patch and the paired connection radiation patches form a circuit. The extracorporal loop radiation patch, the paired connection radiation patches and the patch capacitor are all on a same surface of the extracorporal antenna substrate.

Abstract: A guide is disclosed that operates to guide in the creation of a bone spur to facilitate harvesting a quadriceps tendon and includes an end having a width equal to a desired graft width with a terminal slope equal to a cutting angle desired. In use, the guide may be initially positioned parallel to the femur to form guide cuts in the patella. The guide is then rotated ninety degrees to allow an angled cut at the guide cut. The guide is again rotated, this time one hundred eighty degrees and a second angled cut made on the other guide cut. A final lateral cut is made and the bone spur may be lifted from the patella.

Abstract: The present disclosure provides a dual-blade tendon cutting apparatus and cartridge for multiple apparatuses. Exemplary aspects of the present disclosure relate to a cutting implement that comprises two parallel blades that are spaced apart from one another by a predefined distance. The distance between the blades determines a lateral size of a graft being taken from the quadriceps tendon. To simplify matters for the surgeon, a cartridge is provided with three different blade sets. Much like a razor that has a disposable head, the cutting implement may attach to a desired blade set and be used.

Abstract: A cutting implement includes a V-shaped blade portion that defines an aperture through which a quadriceps tendon may pass as a doctor harvests the tendon through a minimally invasive procedure.

Abstract: A cutting implement includes a V-shaped blade portion that defines an aperture through which a quadriceps tendon may pass as a doctor harvests the tendon through a minimally invasive procedure.

Abstract: Resource authorization policies and resource scopes may be defined separately, thereby decoupling a set of authorization rules from the scope of resources to which those rules apply. In one example, a resource includes anything that can be used in a computing environment (e.g., a file, a device, etc.). A scope describes a set of resources (e.g., all files in folder X, all files labeled “Y”, etc.). Policies describe what can be done with a resource (e.g., “read-only,” “read/write,” “delete, if requestor is a member of the admin group,” etc.). When scopes and policies have been defined, they may be linked, thereby indicating that the policy applies to any resource within the scope. When a request for the resource is made, the request is evaluated against all policies associated with scopes that contain the resource. If the conditions specified in the policies apply, then the request may be granted.

Abstract: The method of delegating authentication, within a chain of entities, relies upon a recording of at least a portion of a TLS handshake between a gateway device and user, in which the user needs access to a desired server. The method then relies upon re-verification of cryptographic evidence in the recorded portion of the TLS handshake, which is forwarded either (1) to the server to which access is desired, in which case the server re-verifies the recorded portion to confirm authentication, or, (2) to a third party entity, in which case the third party entity confirms authentication and provides credentials to the gateway server which then uses the credentials to authenticate to the server as the user.

Abstract: A cutting implement includes a first tubular portion and a second tubular portion. Each tubular portion is hollow and includes a blade element at a distal end. The blade element helps define an aperture that allows access to the interior hollow portion of the tubular portion. A ligament graft element is threaded through the aperture of each tubular portion and the respective tubular portions are interoperated to cut the ligament graft.

Abstract: A cutting implement includes a first tubular portion and a second tubular portion. Each tubular portion is hollow and includes a blade element at a distal end. The blade element helps define an aperture that allows access to the interior hollow portion of the tubular portion. A ligament graft element is threaded through the aperture of each tubular portion and the respective tubular portions are interoperated to cut the ligament graft.

Abstract: A cutting implement includes a V-shaped blade portion that defines an aperture through which a quadriceps tendon may pass as a doctor harvests the tendon through a minimally invasive procedure.

Abstract: A cutting implement includes a first tubular portion and a second tubular portion. Each tubular portion is hollow and includes a blade element at a distal end. The blade element helps define an aperture that allows access to the interior hollow portion of the tubular portion. A ligament graft element is threaded through the aperture of each tubular portion and the respective tubular portions are interoperated to cut the ligament graft.

Abstract: A cutting implement includes a first tubular portion and a second tubular portion. Each tubular portion is hollow and includes a blade element at a distal end. The blade element helps define an aperture that allows access to the interior hollow portion of the tubular portion. A ligament graft element is threaded through the aperture of each tubular portion and the respective tubular portions are interoperated to cut the ligament graft.