Patents by Inventor Paul A. Neff
Paul A. Neff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240075256Abstract: Multi-lumen catheters with first and second expandable members are configured so that one expandable member dilates the Sphincter of Oddi and the second anchors within the biliary duct distal to the Common Bile Duct/Cystic Duct junction or within the cystic duct. The multi-lumen catheters include a primary lumen sized and configured for delivering a flushing agent to remove gallstones together or separately with a dye to complete a Cholangiogram and also include at least one lumen in fluid communication with the first and second expandable members.Type: ApplicationFiled: January 26, 2022Publication date: March 7, 2024Inventors: Lucas Paul Neff, Matthew S. Clifton
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Publication number: 20240058584Abstract: A vascular access disassembling needle assembly is provided that enables rapid insertion of a guide wire into the needle and subsequent rapid removal of the access needle off the guide wire by facile disassembly of the needle. The disassembling needle assembly includes a needle portion wherein the needle breaks apart by splitting along at least one seam that extends from the proximal to the distal end to allow removal of the guide wire. Various mechanical features are described that can facilitate the separation of the needle body along at least one seam. Once one or more seams are separated, the needle body may be removed from the guide wire without the need to withdraw the needle along the length of the guide wire, which permits preloading of expanders and other medical devices onto the guidewire.Type: ApplicationFiled: October 30, 2023Publication date: February 22, 2024Applicant: The Government Of The United States, As Represented By The Secretary Of The Air ForceInventors: Timothy K. Williams, Lucas Paul Neff, James B. Sampson
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Publication number: 20240058009Abstract: Endovascular variable aortic control catheters (EVACC) are provided that are adapted to augment upstream blood pressure and regulate downstream blood flow for patients in shock. The EVACC devices provide improved treatment for truncal wounds, which may be used for example on a battlefield, thereby increasing survivability of injured soldiers. The devices are a catheter-based system having a proximal hand piece for controlled deployment of the device through a delivery sheath. A collapsible, wire framework supports an expandable and collapsible occlusion barrier. The wire basket and occlusion barrier expand to fit within the lumen of the aorta. Various movable elements are used to adjust an adjustable passageway to regulate controlled anterograde blood flow.Type: ApplicationFiled: October 26, 2023Publication date: February 22, 2024Applicant: Government of the United States as Represented by the Secretary of the Air ForceInventors: Timothy K. Williams, Lucas Paul Neff
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Publication number: 20230414220Abstract: Systems and methods for partial aortic occlusion are provided. The system may include a catheter having an expandable aortic blood flow regulation device disposed on the distal end of the catheter for placement within an aorta of a patient, and a catheter controller unit that causes the device to expand and contract to restrict blood flow through the aorta. The system also may include sensors for measuring blood pressure distal and proximal to the expandable device.Type: ApplicationFiled: January 26, 2023Publication date: December 28, 2023Applicants: The Regents of the University of California, Government of the United States as Represented by the Secretary of the Air ForceInventors: Michael Austin Johnson, Timothy K. Williams, Lucas Paul Neff
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Patent number: 11844911Abstract: A vascular access disassembling needle assembly is provided that enables rapid insertion of a guide wire into the needle and subsequent rapid removal of the access needle off the guide wire by facile disassembly of the needle. The disassembling needle assembly includes a needle portion wherein the needle breaks apart by splitting along at least one seam that extends from the proximal to the distal end to allow removal of the guide wire. Various mechanical features are described that can facilitate the separation of the needle body along at least one seam. Once one or more seams are separated, the needle body may be removed from the guide wire without the need to withdraw the needle along the length of the guide wire, which permits preloading of expanders and other medical devices onto the guidewire.Type: GrantFiled: November 17, 2020Date of Patent: December 19, 2023Assignee: United States of America as represented by the Secretary of the Air ForceInventors: Timothy K Williams, Lucas Paul Neff, James B Sampson
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Patent number: 11832826Abstract: Endovascular variable aortic control catheters (EVACC) are provided that are adapted to augment upstream blood pressure and regulate downstream blood flow for patients in shock. The EVACC devices provide improved treatment for truncal wounds, which may be used for example on a battlefield, thereby increasing survivability of injured soldiers. The devices are a catheter-based system having a proximal hand piece for controlled deployment of the device through a delivery sheath. A collapsible, wire framework supports an expandable and collapsible occlusion barrier. The wire basket and occlusion barrier expand to fit within the lumen of the aorta. Various movable elements are used to adjust an adjustable passageway to regulate controlled anterograde blood flow.Type: GrantFiled: April 2, 2019Date of Patent: December 5, 2023Assignee: United States of America as represented by the Secretary of the Air ForceInventors: Timothy K Williams, Lucas Paul Neff
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Publication number: 20230355866Abstract: Systems and methods for Endovascular Perfusion Augmentation for Critical Care (EPACC) are provided. The system may include a catheter having an expandable aortic blood flow regulation device disposed on the distal end of the catheter for placement within an aorta of a patient. The system may also include a catheter controller unit that causes the expandable aortic blood flow regulation device to expand and contract to restrict blood flow through the aorta.Type: ApplicationFiled: December 9, 2022Publication date: November 9, 2023Applicants: The Regents of the University of California, Government of the United States as represented by the Secretary of the Air ForceInventors: Michael Austin Johnson, Lucas Paul Neff, Timothy Williams
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Patent number: 11602592Abstract: Systems and methods for Endovascular Perfusion Augmentation for Critical Care (EPACC) are provided. The system may include a catheter having an expandable aortic blood flow regulation device disposed on the distal end of the catheter for placement within an aorta of a patient. The system may also include a catheter controller unit that causes the expandable aortic blood flow regulation device to expand and contract to restrict blood flow through the aorta.Type: GrantFiled: July 10, 2019Date of Patent: March 14, 2023Assignees: The Regents of the University of California, Government Of The United States As Represented By The Secretary Of The Air ForceInventors: Michael Austin Johnson, Lucas Paul Neff, Timothy Williams
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Patent number: 11596411Abstract: Systems and methods for partial aortic occlusion are provided. The system may include a catheter having an expandable aortic blood flow regulation device disposed on the distal end of the catheter for placement within an aorta of a patient, and a catheter controller unit that causes the device to expand and contract to restrict blood flow through the aorta. The system also may include sensors for measuring blood pressure distal and proximal to the expandable device.Type: GrantFiled: October 18, 2019Date of Patent: March 7, 2023Assignees: The Regents of the University of California, Government of the United States as Represented by the Secretary of the Air ForceInventors: Michael Austin Johnson, Timothy K. Williams, Lucas Paul Neff
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Publication number: 20220000486Abstract: An endovascular occlusion device. The endovascular occlusion device (300) has a balloon (306) and a catheter (304). The catheter (304) has a distal end (308), a proximal end, and a lumen (318) extending therebetween. The balloon (306) is positioned proximate to the distal end (308) of the catheter (304) and has a deflated state and an inflated state. The catheter (304) further includes a plurality of ports (314) proximate to a proximal end of the balloon (306). Each port (314) extends through a wall of the catheter (304) such that surface (316) of the catheter (304) is in fluid communication with the lumen (318) of the catheter (304). A flow restrictor (324) is positioned within, and is in sliding relation with, the lumen (318) of the catheter (304). Movement of the flow restrictor (324) is configured to close one or more ports (314) of the plurality so as to limit blood flow through the lumen (318) of the catheter (304).Type: ApplicationFiled: May 12, 2021Publication date: January 6, 2022Applicant: Government of the United States as represented by the Secretary of the Air ForceInventors: Timothy K. Williams, Lucas Paul Neff
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Publication number: 20210353298Abstract: An endovascular occlusion device. The endovascular occlusion device (300) has a balloon (306) and a catheter (304). The catheter (304) has a distal end (308), a proximal end, and a lumen (318) extending therebetween. The balloon (306) is positioned proximate to the distal end (308) of the catheter (304) and has a deflated state and an inflated state. The catheter (304) further includes a plurality of ports (314) proximate to a proximal end of the balloon (306). Each port (314) extends through a wall of the catheter (304) such that surface (316) of the catheter (304) is in fluid communication with the lumen (318) of the catheter (304). A flow restrictor (324) is positioned within, and is in sliding relation with, the lumen (318) of the catheter (304). Movement of the flow restrictor (324) is configured to close one or more ports (314) of the plurality so as to limit blood flow through the lumen (318) of the catheter (304).Type: ApplicationFiled: May 12, 2021Publication date: November 18, 2021Applicant: Government of the United States as represented by the Secretary of the Air ForceInventors: Timothy K Williams, Lucas Paul Neff
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Publication number: 20210205587Abstract: A vascular access disassembling needle assembly is provided that enables rapid insertion of a guide wire into the needle and subsequent rapid removal of the access needle off the guide wire by facile disassembly of the needle. The disassembling needle assembly includes a needle portion wherein the needle breaks apart by splitting along at least one seam that extends from the proximal to the distal end to allow removal of the guide wire. Various mechanical features are described that can facilitate the separation of the needle body along at least one seam. Once one or more seams are separated, the needle body may be removed from the guide wire without the need to withdraw the needle along the length of the guide wire, which permits preloading of expanders and other medical devices onto the guidewire.Type: ApplicationFiled: November 17, 2020Publication date: July 8, 2021Applicant: Government of the United States as Represented by the Secretary of the Air ForceInventors: Timothy K. Williams, Lucas Paul Neff, James B. Sampson
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Patent number: 10898690Abstract: A vascular access disassembling needle assembly 20 is provided that enables rapid insertion of a guide wire into the needle and subsequent rapid removal of the access needle off the guide wire by facile disassembly of the needle. The disassembling needle assembly 20 includes a needle portion 30 wherein the needle breaks apart by splitting along at least one seam 40 that extends from the proximal to the distal end to allow removal of the guide wire. Various mechanical features are described that can facilitate the separation of the needle body along at least one seam. Once one or more seams are separated, the needle body may be removed from the guide wire without the need to withdraw the needle along the length of the guide wire, which permits preloading of expanders and other medical devices onto the guidewire.Type: GrantFiled: March 20, 2017Date of Patent: January 26, 2021Assignee: The United States of America as represented by the Secretary of the Air ForceInventors: Timothy K Williams, Lucas Paul Neff, James B Sampson
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Publication number: 20200046364Abstract: Systems and methods for partial aortic occlusion are provided. The system may include a catheter having an expandable aortic blood flow regulation device disposed on the distal end of the catheter for placement within an aorta of a patient, and a catheter controller unit that causes the device to expand and contract to restrict blood flow through the aorta. The system also may include sensors for measuring blood pressure distal and proximal to the expandable device.Type: ApplicationFiled: October 18, 2019Publication date: February 13, 2020Applicant: Government of the United States as Represented by the Secretary of the Air ForceInventors: Michael Austin Johnson, Timothy K. Williams, Lucas Paul Neff
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Publication number: 20200038566Abstract: Systems and methods for Endovascular Perfusion Augmentation for Critical Care (EPACC) are provided. The system may include a catheter having an expandable aortic blood flow regulation device disposed on the distal end of the catheter for placement within an aorta of a patient. The system may also include a catheter controller unit that causes the expandable aortic blood flow regulation device to expand and contract to restrict blood flow through the aorta.Type: ApplicationFiled: July 10, 2019Publication date: February 6, 2020Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, DEPARTMENT OF THE AIR FORCEInventors: Michael Austin Johnson, Lucas Paul Neff, Timothy Williams
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Publication number: 20190224396Abstract: Endovascular variable aortic control catheters (EVACC) are provided that are adapted to augment upstream blood pressure and regulate downstream blood flow for patients in shock. The EVACC devices provide improved treatment for truncal wounds, which may be used for example on a battlefield, thereby increasing survivability of injured soldiers. The devices are a catheter-based system having a proximal hand piece for controlled deployment of the device through a delivery sheath. A collapsible, wire framework supports an expandable and collapsible occlusion barrier. The wire basket and occlusion barrier expand to fit within the lumen of the aorta. Various movable elements are used to adjust an adjustable passageway to regulate controlled anterograde blood flow.Type: ApplicationFiled: April 2, 2019Publication date: July 25, 2019Applicant: Government of the United States, as represented by the Secretary of the Air ForceInventors: Timothy K Williams, Lucas Paul Neff
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Publication number: 20190175186Abstract: An endovascular occlusion device. The endovascular occlusion device (300) has a balloon (306) and a catheter (304). The catheter (304) has a distal end (308), a proximal end, and a lumen (318) extending therebetween. The balloon (306) is positioned proximate to the distal end (308) of the catheter (304) and has a deflated state and an inflated state. The catheter (304) further includes a plurality of ports (314) proximate to a proximal end of the balloon (306). Each port (314) extends through a wall of the catheter (304) such that surface (316) of the catheter (304) is in fluid communication with the lumen (318) of the catheter (304). A flow restrictor (324) is positioned within, and is in sliding relation with, the lumen (318) of the catheter (304). Movement of the flow restrictor (324) is configured to close one or more ports (314) of the plurality so as to limit blood flow through the lumen (318) of the catheter (304).Type: ApplicationFiled: June 5, 2017Publication date: June 13, 2019Applicant: Government of the United States as represented by the Secretary of the Air ForceInventors: Timothy K Williams, Lucas Paul Neff
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Patent number: 10279094Abstract: Endovascular variable aortic control catheters (EVACC) are provided that are adapted to augment upstream blood pressure and regulate downstream blood flow for patients in shock. The EVACC devices provide improved treatment for truncal wounds, which may be used for example on a battlefield, thereby increasing survivability of injured soldiers. The devices are a catheter-based system having a proximal hand piece for controlled deployment of the device through a delivery sheath. A collapsible, wire framework supports an expandable and collapsible occlusion barrier. The wire basket and occlusion barrier expand to fit within the lumen of the aorta. Various movable elements are used to adjust an adjustable passageway to regulate controlled anterograde blood flow.Type: GrantFiled: January 7, 2016Date of Patent: May 7, 2019Assignee: United States of America as represented by the Secretary of the Air ForceInventors: Timothy K. Williams, Lucas Paul Neff, James B. Sampson
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Publication number: 20190099587Abstract: A vascular access disassembling needle assembly 20 is provided that enables rapid insertion of a guide wire into the needle and subsequent rapid removal of the access needle off the guide wire by facile disassembly of the needle. The disassembling needle assembly 20 includes a needle portion 30 wherein the needle breaks apart by splitting along at least one seam 40 that extends from the proximal to the distal end to allow removal of the guide wire. Various mechanical features are described that can facilitate the separation of the needle body along at least one seam. Once one or more seams are separated, the needle body may be removed from the guide wire without the need to withdraw the needle along the length of the guide wire, which permits preloading of expanders and other medical devices onto the guidewire.Type: ApplicationFiled: March 20, 2017Publication date: April 4, 2019Applicant: Government of the United States as Represented by the Secretary of the Air ForceInventors: Timothy K Williams, Lucas Paul Neff, James B Sampson
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Publication number: 20160206798Abstract: Endovascular variable aortic control catheters (EVACC) are provided that are adapted to augment upstream blood pressure and regulate downstream blood flow for patients in shock. The EVACC devices provide improved treatment for truncal wounds, which may be used for example on a battlefield, thereby increasing survivability of injured soldiers. The devices are a catheter-based system having a proximal hand piece for controlled deployment of the device through a delivery sheath. A collapsible, wire framework supports an expandable and collapsible occlusion barrier. The wire basket and occlusion barrier expand to fit within the lumen of the aorta. Various movable elements are used to adjust an adjustable passageway to regulate controlled anterograde blood flow.Type: ApplicationFiled: January 7, 2016Publication date: July 21, 2016Applicant: Government of the United States, as represented by the Secretary of the Air ForceInventors: Timothy K. Williams, Lucas Paul Neff, James B. Sampson