Abstract: The invention is directed to methods and compositions for reducing the deposition of pitches and stickies in a papermaking process. The method involves introducing an anionic glycerol-based polymer to the papermaking process. This anionic polymer prevents the pitches and stickies from depositing and agglomerating in papermaking processes.

Abstract: A hybrid system includes a hybrid module that is located between an engine and a transmission. The hybrid system includes an energy storage system for storing energy from and supplying energy to the hybrid module. An inverter transfers power between the energy storage system and the hybrid module. The hybrid system also includes a cooling system, a DC-DC converter, and a high voltage tap. The hybrid module is designed to recover energy, such as during braking, as well as power the vehicle. The hybrid module includes an electrical machine (eMachine) along with electrical and mechanical pumps for circulating fluid. A clutch provides the sole operative connection between the engine and the eMachine. The hybrid system further incorporates a power take off (PTO) unit that is configured to be powered by the engine and/or the eMachine.

Abstract: Optically clear silicone hydrogel contact lenses are described that comprise a polymeric lens body that is the reaction product of a polymerizable composition comprising at least 25 wt. % of at least one hydroxyalkyl methacrylate; and at least 20 wt. % of at least one HEMA-compatible bifunctional polysiloxane comprising at least 6 siloxane groups and having an HLB value of at least 5 and/or a hydroxyl group content of at least 1 wt. %.

Abstract: Systems and methods for managing canisters used to automatically dispense medication are provided. Canisters are configurable via a design process and a build process to accurately dispense a variety of medications. Design profiles are created and stored by a canister management system, and are federated to workstations used to build and fill the canisters, and to workstations used to dispense the medication. Information related to the build process, the fill process, and the dispense process is also federated by the system. The system also enables the transmission of other types of messages between client applications on the workstations and the canister management system. The system is useful to federate data regardless of a structure of a supply chain used to design, build, distribute, and use the canisters.

Abstract: Formulations with anti-tumour action containing defibrotide and at least another active ingredient as active agents.

Abstract: The invention is directed to methods and compositions for reducing the deposition of pitches and stickies in a papermaking process. The method involves introducing an anionic glycerol-based polymer to the papermaking process. This anionic polymer prevents the pitches and stickies from depositing and agglomerating in papermaking processes.

Abstract: The use of defibrotide as an anti-tumor agent, alone or in combination with other active ingredients with anti-tumor action, is described.

Abstract: A hybrid system includes a hybrid module that is located between an engine and a transmission. The hybrid system includes an energy storage system for storing energy from and supplying energy to the hybrid module. An inverter transfers power between the energy storage system and the hybrid module. The hybrid system also includes a cooling system, a DC-DC converter, and a high voltage tap. The hybrid module is designed to recover energy, such as during braking, as well as power the vehicle. The hybrid module includes an electrical machine (eMachine) along with electrical and mechanical pumps for circulating fluid. A clutch provides the sole operative connection between the engine and the eMachine. The hybrid system further incorporates a power take off (PTO) unit that is configured to be powered by the engine and/or the eMachine.

Abstract: A device is provided having a body. The body being made from a flexible material that has an electrical insulating property of at least 1000 volts. A first fastener disposed on a first surface adjacent a first side. A second fastener is disposed on a second surface adjacent a second side, the second surface being opposite the first surface and the second side being opposite the first side. A plurality of straps is coupled to the body.

Abstract: Systems, methods and cartridges for carbonating or otherwise dissolving gas in a precursor liquid, such as water, to form a beverage. A gas source can be provided in a cartridge which is used to generate gas that is dissolved into the precursor liquid. A beverage medium, such as a powdered drink mix or liquid syrup, may be provided in the same, or a separate cartridge as the gas source and mixed with the precursor liquid to form a beverage. The use of one or more cartridges for the gas source and/or beverage medium may make for an easy to use and mess-free system for making sparkling beverages, e.g., in the consumer's home.

Abstract: Systems and methods for managing canisters used to automatically dispense medication are provided. Canisters are configurable via a design process and a build process to accurately dispense a variety of medications. Design profiles are created and stored by a canister management system, and are federated to workstations used to build and fill the canisters, and to workstations used to dispense the medication. Information related to the build process, the fill process, and the dispense process is also federated by the system. The system also enables the transmission of other types of messages between client applications on the workstations and the canister management system. The system is useful to federate data regardless of a structure of a supply chain used to design, build, distribute, and use the canisters.

Abstract: Disclosed painted roof coverings and related methods of manufacturing such painted roof coverings that use a color coating over the roof coverings instead of embedded pre-colored rock granules on the exposed surface of the roof coverings. By painting a roof covering with a color coating, any kind of top surfacing material, such as rock, plastic, mineral, man-made, or organic granules, may be used in place of the pre-colored rock granules. In some embodiments, it is desirable to size the top surfacing material to provide adequate UV protection and coverage to the weatherproofing asphalt material located below the top surfacing material. Further, the color of the shingles may be accurately matched between batches of shingles, between manufacturing facilities, and even between manufacturers. In addition, designs may be painted on the surface of the roof covering, which was previously impossible using pre-colored granules.

Abstract: A building roof monitoring system that includes a fiber optic filament positioned between a water barrier layer (e.g., roof membrane) and a roof substrate layer of the building roof. The fiber optic filament may be part of a sensing layer that includes the fiber optic filament carried by a water transport layer configured to draw water coming into contact with the water transport layer into contact with the fiber optic filament. An optical analyzer injects laser light into the fiber optic filament and detects changes in propagation of the laser light through the fiber optic filament indicative of water coming in contact with the fiber optic filament to detect a roof leak. A response system including a controller, alarm or remote communication unit operatively connected to the optical analyzer responds to the roof leak detected by the optical analyzer.

Abstract: A hybrid system includes a hybrid module that is located between an engine and a transmission. The hybrid system includes an energy storage system for storing energy from and supplying energy to the hybrid module. An inverter transfers power between the energy storage system and the hybrid module. The hybrid system also includes a cooling system, a DC-DC converter, and a high voltage tap. The hybrid module is designed to recover energy, such as during braking, as well as power the vehicle. The hybrid module includes an electrical machine (eMachine) along with electrical and mechanical pumps for circulating fluid. A clutch provides the sole operative connection between the engine and the eMachine. The hybrid system further incorporates a power take off (PTO) unit that is configured to be powered by the engine and/or the eMachine.

Abstract: A filtration system comprising at least one filter element, at least a first and a second filter media that are different to one another and are arranged in a parallel relationship, wherein fluid flow through the filtration system comprises a first fluid flow portion that flows through the first media and a second fluid flow portion that flows through the second media.

Abstract: A particulate material for delivering an active ingredient and a method for making the same is provided. The particulate material can be included in a solid dosage form to provide both high tablet strength and smooth-dissolving mouth-feel. The particulate material includes at least two low moldability sugars, such as, dextrose and sucrose, in an amount of from about 70% to about 100% of the particulate material and is granulated in the presence of a binding agent.

Abstract: A building roof monitoring system that includes a fiber optic filament positioned between a water barrier layer (e.g., roof membrane) and a roof substrate layer of the building roof. The fiber optic filament may be part of a sensing layer that includes the fiber optic filament carried by a water transport layer configured to draw water coming into contact with the water transport layer into contact with the fiber optic filament. An optical analyzer injects laser light into the fiber optic filament and detects changes in propagation of the laser light through the fiber optic filament indicative of water coming in contact with the fiber optic filament to detect a roof leak. A response system including a controller, alarm or remote communication unit operatively connected to the optical analyzer responds to the roof leak detected by the optical analyzer.

Abstract: The present invention relates to an amyloid ? peptide analogues comprising an amino acid sequence or a peptidomimetic thereof, wherein the sequence (i) forms a loop, (ii) has at least 66% identity to the amino acid sequence of native A? peptide or a portion thereof, (iii) comprises at least 6 contiguous amino acid residues and (iv) has at least 2 non-contiguous amino acid residues which are covalently linked with each other, oligomers comprising a plurality of said amyloid ? peptide analogues, processes for preparing the amyloid ? peptide analogues or oligomers, compositions comprising the amyloid ? peptide analogues or oligomers, and uses of the amyloid ? peptide analogues or oligomers such as their use for treating or preventing an amyloidosis (e.g. by active immunization), for diagnosing an amyloidosis, and for providing agents that are capable of binding to the amyloid ? peptide analogues or oligomers.

Abstract: The present invention relates to a pharmacologic dosage unit which includes a multi-functional particulate system and a pharmacologically active agent. The multi-functional particulate system includes solid biologically-safe particles incorporated into a matrix and having a characteristic that each individual particle retains its original size. The invention also relates to methods of preparing, enhancing flow properties and compacting properties of a pharmacologic composition, increasing capacity for inclusion of ingredients, and increasing dispersion of actives. Finally, the invention includes a method for delivering an active agent to a patient.